Gene Information gene info

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GENE：CNOT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CNOT2
FullNmae CCR4-NOT transcription complex subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7878
EnsembleID ENSG00000111596
Uniprot Q9NZN8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CNOT2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNOT2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CNOT2 GO:0000122,GO:0000289,GO:0000289,GO:0000932,GO:0001222,GO:0001829,GO:0003712,GO:0004535,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0006357,GO:0010606,GO:0016020,GO:0030014,GO:0030014,GO:0030015,GO:0031047,GO:0033147,GO:2000036,GO:2000036

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CNOT2 hsa:4848 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 CNOT2 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 CNOT2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CNOT2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CNOT2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CNOT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000251D0B CNOT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000CF1D2 CNOT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 CNOT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000045B99E CNOT2 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 CNOT2 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 CNOT2 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F CNOT2 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 CNOT2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 CNOT2 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 CNOT2 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATR CNOT2 22135298 phosphorylation N/A PhosphoSite
CNOT3 CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 CNOT3 25361965 interaction type N/A PTMCode2
CNOT2 CNOT6 25361965 interaction type N/A PTMCode2
CNOT6 CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 CNOT6L 25361965 interaction type N/A PTMCode2
CNOT6L CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 CNOT1 25361965 interaction type N/A PTMCode2
CNOT1 CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 CNOT10 25361965 interaction type N/A PTMCode2
CNOT10 CNOT2 25361965 interaction type N/A PTMCode2
CNOT2 CNOT7 25361965 interaction type N/A PTMCode2
CNOT7 CNOT2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NANOS2 CNOT2 25348397 N/A physical interaction ComPPI
VCP CNOT2 25348397 N/A physical interaction ComPPI
CNKSR3 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LARP1 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RACK1 CNOT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NLK CNOT2 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EGLN3 CNOT2 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
MMP7 CNOT2 25348397 N/A physical interaction ComPPI
TOB1 CNOT2 18377426 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HDAC3 CNOT2 16712523 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FHL2 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOR2 CNOT2 25348397 N/A physical interaction ComPPI
NCOR1 CNOT2 25348397 N/A physical interaction ComPPI
GADD45B CNOT2 25348397 N/A physical interaction ComPPI
BTRC CNOT2 25348397 N/A physical interaction ComPPI
EIF6 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL12 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLD1 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AURKA CNOT2 25348397 N/A physical interaction ComPPI
GPS2 CNOT2 16712523 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KLKB1 CNOT2 25348397 N/A physical interaction ComPPI
UPF1 CNOT2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
SS18 CNOT2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
NFKB1 CNOT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CSTF2 CNOT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDB1 CNOT2 25348397 N/A physical interaction ComPPI
CNOT7 CNOT2 24234451 25348397 physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CNOT8 CNOT2 14525934 16778766 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
AKIP1 CNOT2 25348397 N/A physical interaction ComPPI
MRPS12 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNKS1BP1 CNOT2 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT1 CNOT2 10637334 12215531 14525934 16263706 16778766 19707589 20386698 21669201 24121231 24234451 25348397 26496610 27898060 7926748 9463387 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct,OmniPath
CNOT2 CNOT3 14525934 16189514 16778766 21984185 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
CNOT2 CNOT6L 17452450 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT2 CNOT6 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CNOT2 CAPZA2 25348397 N/A physical interaction ComPPI
CNOT2 WRAP73 25348397 N/A physical interaction ComPPI
CNOT2 TNRC6C 21981923 21984185 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CNOT2 TNRC6A 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT2 TNRC6B 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT2 AGO2 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT2 CAPZB 25348397 N/A physical interaction ComPPI
CNOT2 CACNA2D1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT2 DDX12P 25348397 N/A physical interaction ComPPI
CNOT2 DDX11 25348397 N/A physical interaction ComPPI
CNOT2 CNOT9 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CNOT2 USP24 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT2 CNOT10 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CNOT2 SS18L2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT2 CNOT11 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT2 KANSL3 25348397 N/A physical interaction ComPPI
CNOT2 TMEM165 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT2 DDX24 25348397 N/A physical interaction ComPPI
CNOT2 WDR26 25348397 N/A physical interaction ComPPI
CNOT2 LCOR 25348397 N/A physical interaction ComPPI
CNOT2 RC3H1 25348397 N/A physical interaction ComPPI
CNOT2 RIBC1 25348397 N/A physical interaction ComPPI
CNOT2 GPBP1L1 25348397 N/A physical interaction ComPPI
CNOT2 GLA 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT2 ARMC5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CNOT2 GCSAM 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CNOT2 C11ORF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CNOT2 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CNOT2 BCL6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CNOT2 PRR35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OBI1 CNOT2 25348397 N/A physical interaction ComPPI
HSCB CNOT2 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
TEKT3 CNOT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TEX13A CNOT2 25348397 N/A physical interaction ComPPI
STK38L CNOT2 24234451 30108113 association proximity-dependent biotin identification IntAct

Source Target Pmid Interactiontype Methods Database
URS00009BD51C CNOT2 27087310 direct interaction,inhibition N/A NPInter

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