Gene Information gene info

GENE:MTMR3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTMR3
FullNmae myotubularin related protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7451
EnsembleID ENSG00000100330
Uniprot Q13615

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTMR3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTMR3 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTMR3 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MTMR3 GO:0004438,GO:0004438,GO:0004438,GO:0004722,GO:0004722,GO:0004725,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0006470,GO:0006661,GO:0008138,GO:0010506,GO:0016020,GO:0016020,GO:0016236,GO:0019903,GO:0019903,GO:0042149,GO:0046856,GO:0046856,GO:0046872,GO:0052629,GO:0052629,GO:0052629,GO:0060304,GO:1904562,GO:2000785

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MTMR3 hsa:8897 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
MTMR3 hsa:8897 path:hsa01100 Metabolic pathways - Homo sapiens (human)
MTMR3 hsa:8897 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)
MTMR3 hsa:8897 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MTMR3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 MTMR3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MTMR3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 MTMR3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MTMR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D MTMR3 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS00000BE495 MTMR3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 MTMR3 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS0000330617 MTMR3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039E1E1 MTMR3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA MTMR3 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS0000157026 MTMR3 23731011 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000042E1F MTMR3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 MTMR3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 MTMR3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MTMR3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001496AE MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 MTMR3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A MTMR3 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000170CF4 MTMR3 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000049704B MTMR3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000E732F MTMR3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000585553 MTMR3 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EXOSC5 MTMR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GOLGA2 MTMR3 24234451 25348397 26787466 colocalization fluorescence microscopy ComPPI,IntAct
EXOSC1 MTMR3 12419256 24234451 25348397 physical association two hybrid ComPPI,IntAct
EXOSC8 MTMR3 12419256 24234451 25348397 physical association two hybrid ComPPI,IntAct
EGLN3 MTMR3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
FGFR2 MTMR3 25348397 N/A physical interaction ComPPI
ORC4 MTMR3 25348397 N/A physical interaction ComPPI
CUL3 MTMR3 25348397 N/A physical interaction ComPPI
SSBP1 MTMR3 25348397 N/A physical interaction ComPPI
PLK1 MTMR3 25348397 N/A physical interaction ComPPI
ATM MTMR3 25348397 N/A physical interaction ComPPI
ALOX5 MTMR3 25348397 N/A physical interaction ComPPI
AURKA MTMR3 25348397 N/A physical interaction ComPPI
HIVEP1 MTMR3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRIM25 MTMR3 25348397 N/A physical interaction ComPPI
EYA3 MTMR3 25348397 N/A physical interaction ComPPI
MTOR MTMR3 24234451 25348397 26787466 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MLST8 MTMR3 24234451 25348397 26787466 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC7 MTMR3 12419256 24234451 25348397 physical association two hybrid ComPPI,IntAct
RPTOR MTMR3 24234451 25348397 26787466 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED18 MTMR3 25348397 N/A physical interaction ComPPI
HEATR1 MTMR3 25348397 N/A physical interaction ComPPI
NUP205 MTMR3 25348397 N/A physical interaction ComPPI
PNO1 MTMR3 25348397 N/A physical interaction ComPPI
KSR1 MTMR3 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
MTMR4 MTMR3 25348397 N/A physical interaction ComPPI
WRAP73 MTMR3 25348397 N/A physical interaction ComPPI
ANKRD28 MTMR3 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IPO5 MTMR3 25348397 N/A physical interaction ComPPI
LONRF1 MTMR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THOC2 MTMR3 25348397 N/A physical interaction ComPPI
MTMR3 TULP3 25348397 N/A physical interaction ComPPI
MTMR3 MTOR 26787466 27898060 inhibition N/A OmniPath

Visualization