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GENE：RAB6A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAB6A
FullNmae RAB6A, member RAS oncogene family
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9786
EnsembleID ENSG00000175582
Uniprot P20340

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAB6A pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAB6A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAB6A GO:0000139,GO:0000139,GO:0002080,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005789,GO:0005794,GO:0005794,GO:0005802,GO:0005829,GO:0005829,GO:0005886,GO:0006886,GO:0006890,GO:0006890,GO:0006890,GO:0006891,GO:0012505,GO:0016020,GO:0018125,GO:0019882,GO:0019904,GO:0030667,GO:0031175,GO:0031410,GO:0031489,GO:0032588,GO:0034067,GO:0034498,GO:0042147,GO:0051179,GO:0070062,GO:0070381,GO:0072385,GO:1903292

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 RAB6A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RAB6A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 RAB6A N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 RAB6A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000237AF9 RAB6A 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000ED600 RAB6A 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 RAB6A 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000009262D RAB6A 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000005481D RAB6A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065FDF RAB6A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 RAB6A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D RAB6A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D50C RAB6A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D RAB6A 25416803 27144577 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
RAB6A ERC1 25361965 interaction type N/A PTMCode2
ERC1 RAB6A 25361965 interaction type N/A PTMCode2
RAB6A DCTN1 25361965 interaction type N/A PTMCode2
DCTN1 RAB6A 25361965 interaction type N/A PTMCode2
RAB6A OCRL 25361965 interaction type N/A PTMCode2
OCRL RAB6A 25361965 interaction type N/A PTMCode2
RAB6A GOLGA1 25361965 interaction type N/A PTMCode2
GOLGA1 RAB6A 25361965 interaction type N/A PTMCode2
RAB6A RABGAP1 25361965 interaction type N/A PTMCode2
RABGAP1 RAB6A 25361965 interaction type N/A PTMCode2
RAB6A KIF20A 25361965 interaction type N/A PTMCode2
KIF20A RAB6A 25361965 interaction type N/A PTMCode2
BICD1 RAB6A 25361965 interaction type N/A PTMCode2
RAB6A BICD1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 RAB6A 25348397 N/A physical interaction ComPPI
GOLGA1 RAB6A 10209123 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TOMM22 RAB6A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RABGGTB RAB6A 14525934 25348397 8175798 N/A experimental interaction detection,in vitro ComPPI,HPRD
RABAC1 RAB6A 10329441 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
TGFBR2 RAB6A 25348397 N/A physical interaction ComPPI
RAB8A RAB6A 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB7A RAB6A 25348397 N/A physical interaction ComPPI
HAX1 RAB6A 25348397 N/A physical interaction ComPPI
RPA1 RAB6A 25348397 N/A physical interaction ComPPI
TMF1 RAB6A 14525934 15128430 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
DCTN1 RAB6A 12401177 14525934 16473624 16902405 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
NPHP1 RAB6A 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RAB1A RAB6A 25348397 N/A physical interaction ComPPI
CHM RAB6A 14525934 25348397 8294464 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SYTL5 RAB6A 12051743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RAB2A RAB6A 25348397 N/A physical interaction ComPPI
GDI1 RAB6A 14525934 25348397 8175798 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RAB6A GOLGA4 10209123 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAB6A ERC1 11929610 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAB6A RABGAP1 10202141 11071909 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
RAB6A KIF20A 11071909 14525934 16473624 25348397 27898060 9438855 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
RAB6A BICD2 12401177 12447383 14525934 16473624 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RAB6A CHML 14525934 25348397 8294464 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RAB6A OCRL 14525934 16902405 21378754 24234451 25107275 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,fluorescence polarization spectroscopy,molecular sieving,pull down,physical interaction,enzyme linked immunosorbent assay,in vitro,in vivo,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
RAB6A BICD1 12401177 12447383 14525934 16473624 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
RAB6A ELAVL1 25348397 N/A physical interaction ComPPI
RAB6A RPA3 25348397 N/A physical interaction ComPPI
RAB6A RPA2 25348397 N/A physical interaction ComPPI
RAB6A SRPRB 25348397 N/A physical interaction ComPPI
RAB6A DNAAF2 25348397 N/A physical interaction ComPPI
RAB6A TREML2 25348397 N/A physical interaction ComPPI
RAB6A RNF26 25348397 N/A physical interaction ComPPI
RAB6A TMEM52B 25348397 N/A physical interaction ComPPI
RAB6A RAB11B 25348397 N/A physical interaction ComPPI
RAB6A ARF1 25348397 N/A physical interaction ComPPI
RAB6A ETFA 25348397 N/A physical interaction ComPPI
RAB6A RAB1C 25348397 N/A physical interaction ComPPI
RAB6A RAB1B 25348397 N/A physical interaction ComPPI
RAB6A OFD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RAB6A RPGRIP1L 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RAB6A ZNF131 25348397 N/A physical interaction ComPPI
RAB6A RAB6B 25348397 N/A physical interaction ComPPI
RAB6A TRIM25 25348397 N/A physical interaction ComPPI
RAB6A VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RAB6A HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RAB6A GCC2 18243103 24234451 25348397 27898060 N/A affinity chromatography technology,isothermal titration calorimetry,x-ray crystallography ComPPI,IntAct,OmniPath
RAB6A CAT 23333653 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
RAB6A BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RAB6A RAB11A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RAB6A RAB9A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RAB6A TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FKBP2 RAB6A 25348397 N/A physical interaction ComPPI
PMM1 RAB6A 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
H2BC9 RAB6A 24234451 30021884 physical association cross-linking study IntAct

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