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GENE：RARB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RARB
FullNmae retinoic acid receptor beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9865
EnsembleID ENSG00000077092
Uniprot P10826

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RARB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RARB GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0001657,GO:0002068,GO:0003417,GO:0003677,GO:0004879,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006915,GO:0007165,GO:0008270,GO:0009755,GO:0021756,GO:0022008,GO:0030154,GO:0031641,GO:0032331,GO:0035116,GO:0035264,GO:0043065,GO:0044877,GO:0045944,GO:0046965,GO:0048048,GO:0048384,GO:0048566,GO:0055012,GO:0061351,GO:0072089,GO:1990837,GO:2000647

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RARB hsa:5915 path:hsa05200 Pathways in cancer - Homo sapiens (human)
RARB hsa:5915 path:hsa05222 Small cell lung cancer - Homo sapiens (human)
RARB hsa:5915 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
RARB hsa:5915 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RARB RXRA 12576329 20102612 23180781 23331499 7565739 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
KDM5B RARB 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
EZH2 RARB 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
NCOA3 RARB 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
RARA RARB 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
NR0B2 RARB 11368516 23331499 stimulation N/A SignaLink
THRA RARB 15650024 23331499 stimulation N/A SignaLink
RARB THRA 15650024 23331499 stimulation N/A SignaLink
RXRA RARB 14691372 23331499 stimulation N/A SignaLink
RARB RXRB 12112017 1331778 15604093 23331499 stimulation N/A SignaLink
RXRB RARB 12112017 15604093 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR RARB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
MYC RARB 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C RARB 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CREB1 RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RARA RARB 10629091 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TBP RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RARB RARB 12767074 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 RARB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXD3 RARB 23058321 trascriptional regulation,stimulation inferred by curator TFlink
HDAC1 RARB 14731134 trascriptional regulation,stimulation inferred by curator TFlink
JUN RARB 9377582 trascriptional regulation,stimulation inferred by curator TFlink
PPARG RARB 12839938 trascriptional regulation,stimulation inferred by curator TFlink
RARG RARB 1310259 trascriptional regulation,stimulation inferred by curator TFlink
SNW1 RARB 19934264 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000017EE98 RARB 20309880 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS0000171CD1 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 RARB 25074381 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002C02E4 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 RARB 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 RARB 25416803 27342319 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001EFBE3 RARB 25416803 27011326 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000050CCE0 RARB 25416803 27011326 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CCNH RARB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SMARCE1 RARB 25348397 N/A physical interaction ComPPI
RARA RARB 25348397 N/A physical interaction ComPPI
RXRG RARB 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid prey pooling approach,two hybrid ComPPI,HPRD
RARB MEOX2 25348397 N/A two hybrid,physical interaction,two hybrid prey pooling approach ComPPI
RARB NCOA1 12665583 14525934 25348397 8754792 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RARB CEBPA 25348397 N/A physical interaction ComPPI
RARB CEBPB 25348397 N/A physical interaction ComPPI
RARB GATA3 25348397 N/A physical interaction ComPPI
RARB HR 25348397 N/A physical interaction ComPPI
RARB RXRA 14525934 25348397 7565739 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RARB NCOR2 25348397 N/A physical interaction ComPPI
RARB RXRB 1331778 14525934 15604093 25348397 N/A experimental interaction detection,physical interaction,two hybrid prey pooling approach,two hybrid ComPPI,HPRD
RARB PNRC1 14525934 15604093 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
RARB MAP6 14525934 15604093 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
RARB HACE1 25348397 N/A physical interaction ComPPI
RARB SMAD2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RARB PRKD2 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RARB ITGB1BP2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RARB ARID1A 25348397 N/A physical interaction ComPPI
RARB SMARCD3 25348397 N/A physical interaction ComPPI
RARB PSMC5 25348397 N/A two hybrid,physical interaction ComPPI
RARB ZNF423 19345331 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RARB ASXL1 16606617 24234451 25348397 N/A pull down ComPPI,IntAct
RARB ESR1 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
RARB ESR2 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
RARB CCNDBP1 25348397 N/A two hybrid ComPPI
RARB PPARGC1A 25348397 N/A two hybrid ComPPI
NCOA3 RARB 12665583 14525934 N/A experimental interaction detection HPRD
RARB RXRA 12576329 1310351 14691372 27898060 7565739 stimulant N/A OmniPath
RXRA RARB 12576329 1310351 14691372 27898060 7565739 stimulant N/A OmniPath
NR0B2 RARB 11368516 27898060 stimulant N/A OmniPath
RARB RXRB 12112017 1310351 1331778 1560409 15604093 25416956 27898060 stimulant N/A OmniPath
RXRB RARB 12112017 1310351 1331778 1560409 15604093 25416956 27898060 stimulant N/A OmniPath
RARB THRA 15650024 27898060 stimulant N/A OmniPath
THRA RARB 15650024 27898060 stimulant N/A OmniPath

Visualization










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