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GENE：SMURF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SMURF2
FullNmae SMAD specific E3 ubiquitin protein ligase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16809
EnsembleID ENSG00000108854
Uniprot Q9HAU4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SMURF2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SMURF2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SMURF2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SMURF2 GO:0000122,GO:0000151,GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006511,GO:0006511,GO:0016567,GO:0016567,GO:0016607,GO:0017015,GO:0030512,GO:0030512,GO:0030514,GO:0030514,GO:0042802,GO:0043161,GO:0045121,GO:0045892,GO:0046332,GO:0060071,GO:0061630,GO:0061630,GO:0090263,GO:1901165

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SMURF2 hsa:64750 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
SMURF2 hsa:64750 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
SMURF2 hsa:64750 path:hsa04144 Endocytosis - Homo sapiens (human)
SMURF2 hsa:64750 path:hsa04340 Hedgehog signaling pathway - Homo sapiens (human)
SMURF2 hsa:64750 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
SMURF2 hsa:64750 path:hsa04520 Adherens junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMURF2 TGFBR1 14722617 15265520 22624557 26192618 interaction type,ubiquitination reaction,inhibition N/A ACSN,SignaLink
SMAD2 SMURF2 11389444 18729074 19122240 19620243 20937913 23180781 23331499 interaction type,physical association tandem affinity purification InnateDB,SignaLink
SMAD3 SMURF2 18729074 23180781 physical association tandem affinity purification InnateDB
LAPTM5 SMURF2 15231748 23180781 physical association two hybrid InnateDB
RNF11 SMURF2 15231748 23180781 physical association two hybrid InnateDB
SMURF2 SMURF2 11016919 11163210 11389444 17317136 18448069 22298955 26467481 ubiquitination reaction,down-regulates activity N/A Signor
SMURF2 SMAD7 22921829 interaction type,stimulation N/A SignaLink
SMURF2 SMAD2 11016919 11158580 14507671 15221015 15231748 19620243 23331499 stimulation N/A SignaLink
SMURF2 SMAD1 11016919 11158580 14701756 15221015 15231748 23331499 stimulation N/A SignaLink
SMAD7 SMURF2 11163210 18448069 20937913 23331499 stimulation N/A SignaLink
SMURF2 SKIL 11389444 23331499 stimulation N/A SignaLink
SMURF2 CTNNB1 16950122 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
FLNB SMURF2 20005715 interaction type N/A PSP
SOCS6 SMURF2 20005715 interaction type N/A PSP
SQSTM1 SMURF2 20005715 interaction type N/A PSP,SignaLink
FLNB SMURF2 15231748 18988627 20005715 N/A N/A SignaLink
SOCS6 SMURF2 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR SMURF2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SMURF2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SMURF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SMURF2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SMURF2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SMURF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC SMURF2 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000028DE3F SMURF2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB SMURF2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SMURF2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D SMURF2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D SMURF2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 SMURF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 SMURF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 SMURF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D12AC SMURF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 SMURF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 SMURF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 SMURF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 SMURF2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RAP1A SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 RAP1A 25361965 interaction type N/A PTMCode2
SMAD7 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 SMAD7 25361965 interaction type N/A PTMCode2
SMURF2 RNF111 25361965 interaction type N/A PTMCode2
RNF111 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 SMAD6 25361965 interaction type N/A PTMCode2
SMAD6 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 RPS27A 25361965 interaction type N/A PTMCode2
RPS27A SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 UBE2L3 25361965 interaction type N/A PTMCode2
UBE2L3 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 STAMBP 25361965 interaction type N/A PTMCode2
STAMBP SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 PRICKLE1 25361965 interaction type N/A PTMCode2
PRICKLE1 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 RNF2 25361965 interaction type N/A PTMCode2
RNF2 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 AIMP1 25361965 interaction type N/A PTMCode2
AIMP1 SMURF2 25361965 interaction type N/A PTMCode2
RNF11 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 RNF11 25361965 interaction type N/A PTMCode2
SKIL SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 SKIL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I SMURF2 25348397 N/A physical interaction ComPPI
DES SMURF2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
AIMP2 SMURF2 25348397 N/A physical interaction ComPPI
RAB14 SMURF2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNNI3 SMURF2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
ATP5F1B SMURF2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SKIL SMURF2 11389444 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
UXT SMURF2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
RAN SMURF2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBE2D1 SMURF2 25348397 N/A physical interaction ComPPI
SMAD4 SMURF2 25348397 N/A physical interaction ComPPI
SLC25A6 SMURF2 25348397 N/A physical interaction ComPPI
EIF3E SMURF2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
LAPTM5 SMURF2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PRICKLE1 SMURF2 14525934 19379695 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 ARHGAP5 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 TXNIP 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 DAB2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 DGCR2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 ABRAXAS2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 ACBD3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 SF3A2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 ACOX3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 RNF111 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 TMEM139 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 SNRNP70 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 RUNX3 25348397 N/A physical interaction,in vivo ComPPI
SMURF2 SMAD2 11016919 14525934 15231748 18729074 20937913 22045334 24234451 25348397 physical association two hybrid,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,peptide array,physical interaction,in vitro,in vivo,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
SMURF2 SMAD1 11016919 14525934 14701756 15231748 20937913 24234451 25348397 physical association two hybrid,experimental interaction detection,nuclear magnetic resonance,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
SMURF2 SMAD7 11163210 14525934 15231748 17719543 20937913 22921829 24234451 25348397 physical association classical fluorescence spectroscopy,two hybrid,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,in vitro,in vivo,ion mobility mass spectrometry of complexes,two hybrid ComPPI,HPRD,IntAct
SMURF2 SMAD3 11016919 14525934 18729074 22045334 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,peptide array,physical interaction,two hybrid array,in vitro,tandem affinity purification,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
SMURF2 RNF11 14525934 14755250 15231748 20676133 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SMURF2 ANAPC5 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 ASH2L 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 EPHA1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 FKBP4 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 GNG2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 HDGFL3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 ING2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 IRF3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 IRF8 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 NEK6 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 NKIRAS1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 NRAS 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RAB13 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RAB17 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RAB25 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RASD2 25348397 N/A in vivo ComPPI
SMURF2 RASL12 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RHOD 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RNF2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RRAS2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 SRSF4 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 SMAD6 14525934 15231748 15761153 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SMURF2 SMAP1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 SOCS6 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 TSSK4 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 RAP1B 14525934 17318188 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SMURF2 TRAF2 14525934 18671942 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SMURF2 PRICKLE2 14525934 19379695 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF2 TRAF4 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 DAZAP2 14525934 15231748 22070932 24234451 25348397 27898060 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct,OmniPath
SMURF2 FLNB 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 TNPO3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 SMAD5 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 ZBTB44 14525934 15231748 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SMURF2 SPART 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 TFPI2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 CANX 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 CUEDC1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMURF2 STAMBP 14755250 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMURF2 TGFBR1 11163210 14525934 14722617 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SMURF2 TGFBR2 25348397 N/A physical interaction ComPPI
SMURF2 SMURF1 25348397 N/A physical interaction ComPPI
SMURF2 TNFRSF1B 25348397 N/A physical interaction ComPPI
SMURF2 AIMP1 25348397 N/A physical interaction ComPPI
SMURF2 UBE2L3 25348397 N/A physical interaction ComPPI
SMURF2 NEDD4 25348397 N/A nuclear magnetic resonance,physical interaction,physical interaction ComPPI
SMURF2 GSK3B 25348397 N/A physical interaction ComPPI
SMURF2 ID1 25348397 N/A physical interaction ComPPI
SMURF2 KLF5 21953463 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMURF2 EGFR 25348397 N/A physical interaction ComPPI
SMURF2 AXIN1 25348397 N/A physical interaction ComPPI
SMURF2 RUNX2 25348397 N/A physical interaction ComPPI
SMURF2 RLIM 21945933 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMURF2 USP15 25348397 N/A physical interaction ComPPI
SMURF2 CCM2 25348397 N/A physical interaction ComPPI
SMURF2 UBE2D3 25348397 N/A physical interaction ComPPI
SMURF2 HSPB1 25348397 N/A physical interaction ComPPI
SMURF2 EFNB1 25348397 N/A physical interaction ComPPI
SMURF2 FBXL15 21572392 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SMURF2 UBC 19343052 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
SMURF2 MRPS22 25348397 N/A physical interaction ComPPI
SMURF2 YBX1 25348397 N/A physical interaction ComPPI
SMURF2 ACTA2 25348397 N/A physical interaction ComPPI
SMURF2 SMARCA2 25348397 N/A physical interaction ComPPI
SMURF2 ENAH 25348397 N/A physical interaction ComPPI
SMURF2 MRPS7 25348397 N/A physical interaction ComPPI
SMURF2 MYLK2 25348397 N/A physical interaction ComPPI
SMURF2 RBM14 25348397 N/A physical interaction ComPPI
SMURF2 KCTD12 25348397 N/A physical interaction ComPPI
SMURF2 MRPS31 25348397 N/A physical interaction ComPPI
SMURF2 SLC25A5 25348397 N/A physical interaction ComPPI
SMURF2 ESF1 25348397 N/A physical interaction ComPPI
SMURF2 DNAJC10 25348397 N/A physical interaction ComPPI
SMURF2 UBA52 25348397 N/A pull down,physical interaction,physical interaction ComPPI
SMURF2 MAVS 24729608 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMURF2 BTRC 25348397 N/A physical interaction ComPPI
SMURF2 YY1 24803334 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMURF2 PTCH1 25348397 N/A physical interaction ComPPI
SMURF2 LATS1 25348397 N/A physical interaction ComPPI
SMURF2 LDLRAD4 25348397 N/A physical interaction ComPPI
SMURF2 UBE2D2 25348397 N/A physical interaction ComPPI
SMURF2 PIAS3 25348397 N/A physical interaction ComPPI
SMURF2 GLIS3 25348397 N/A physical interaction ComPPI
SMURF2 NEDD9 25348397 N/A physical interaction ComPPI
SMURF2 PRMT1 25348397 N/A physical interaction ComPPI
SMURF2 FUBP1 25348397 N/A physical interaction ComPPI
SMURF2 XPO1 25348397 N/A physical interaction ComPPI
SMURF2 NEDD8 25348397 N/A physical interaction ComPPI
SMURF2 SETD7 25348397 N/A physical interaction ComPPI
SMURF2 SEMG2 25348397 N/A physical interaction ComPPI
SMURF2 MARS2 25348397 N/A physical interaction ComPPI
SMURF2 LINGO2 25348397 N/A physical interaction ComPPI
SMURF2 SKI 25348397 N/A physical interaction ComPPI
SMURF2 TOP2A 25348397 N/A physical interaction ComPPI
SMURF2 HNRNPL 25348397 N/A physical interaction ComPPI
SMURF2 NEBL 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 TTN 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 CCAR1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 FLNC 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 FHL2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 GMEB1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 EEF1G 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 ECHS1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 GFM1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 DCAF6 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 MRPL2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 SQSTM1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 NOMO1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 MYBPC3 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 MRPL19 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 NDUFA1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 TCAP 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 ACTA1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 TNNT1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 NEB 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 TNNI2 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 MYOZ1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 LMCD1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 MRPL41 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMURF2 PARD6A 19379695 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SMURF2 RTN4IP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOA SMURF2 17719543 20026602 21402695 24234451 25348397 27898060 enzymatic reaction physical interaction,enzymatic study ComPPI,IntAct,OmniPath
UBB SMURF2 14755250 17719543 24234451 25348397 ubiquitination reaction,enzymatic reaction anti tag coimmunoprecipitation,pull down,physical interaction,enzymatic study ComPPI,IntAct
RPS27A SMURF2 14525934 14755250 25348397 N/A experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD
ITGB1BP1 SMURF2 25348397 N/A physical interaction ComPPI
ID3 SMURF2 25348397 N/A physical interaction ComPPI
ILF2 SMURF2 25348397 N/A physical interaction ComPPI
RAB22A SMURF2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PPID SMURF2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RNF20 SMURF2 22231558 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MRPS23 SMURF2 25348397 N/A physical interaction ComPPI
SMURF2 SMURF2 14525934 15231748 17719543 24234451 enzymatic reaction,physical association two hybrid,experimental interaction detection,nuclear magnetic resonance,pull down,enzymatic study HPRD,IntAct
SMURF2 CTNNB1 16950122 27898060 stimulant N/A OmniPath
SMURF2 TGFBR2 11163210 22298955 25149540 27898060 inhibition N/A OmniPath
SMURF2 SMAD1 11016919 11158580 14701756 15221015 15231748 20937913 20956305 22298955 23969857 27898060 inhibition,stimulant N/A OmniPath
SMURF2 SMAD5 15221015 15231748 20484049 22298955 27898060 inhibition N/A OmniPath
SMAD2 SMURF2 11016919 11158580 11389444 14507671 15221015 15231748 18729074 19122240 19620243 20937913 22045334 27898060 stimulant N/A OmniPath
SMURF2 SMAD2 11016919 11158580 11389444 14507671 15221015 15231748 18729074 19122240 19620243 20937913 22045334 27898060 inhibition,stimulant N/A OmniPath
SMURF2 TGFBR1 11163210 14722617 17317136 17347560 20386537 21791611 22624557 23973329 25149540 26679521 27898060 inhibition N/A OmniPath
SMURF2 SMAD9 22298955 27898060 inhibition N/A OmniPath
SMURF2 BMPR1A 22298955 27898060 inhibition N/A OmniPath
AIMP1 SMURF2 18448069 27898060 stimulant N/A OmniPath
SMAD7 SMURF2 11163210 14722617 15173588 15221015 15231748 16061177 16641086 17347560 17719543 18448069 19352540 20386537 20937913 21791611 22624557 22773947 22921829 23973329 25612247 25885904 26679521 27898060 stimulant N/A OmniPath
SMURF2 SMAD7 11163210 14722617 15173588 15221015 15231748 16061177 16641086 17347560 17719543 18448069 19352540 20386537 20937913 21791611 22624557 22773947 22921829 23973329 25612247 25885904 26679521 27898060 inhibition N/A OmniPath
SMURF2 SKIL 11389444 27898060 inhibition,stimulant N/A OmniPath
SMURF2 BMPR2 22298955 27898060 inhibition N/A OmniPath

Visualization










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