Gene Information gene info

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GENE：SRGN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SRGN
FullNmae serglycin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9361
EnsembleID ENSG00000122862
Uniprot P10124

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SRGN autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SRGN GO:0001818,GO:0005515,GO:0005576,GO:0005615,GO:0005794,GO:0006915,GO:0016485,GO:0030141,GO:0030502,GO:0030502,GO:0031093,GO:0031214,GO:0033363,GO:0033364,GO:0033371,GO:0033373,GO:0033382,GO:0042629,GO:0044194,GO:0050804,GO:0098685,GO:0098978,GO:0099091,GO:0099175,GO:0140507

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 SRGN 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SRGN 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SRGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SRGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SRGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SRGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SRGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SRGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SRGN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 SRGN 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000075B538 SRGN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 SRGN 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 SRGN 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GZMB SRGN 25361965 interaction type N/A PTMCode2
SRGN GZMB 25361965 interaction type N/A PTMCode2
SRGN CD44 25361965 interaction type N/A PTMCode2
CD44 SRGN 25361965 interaction type N/A PTMCode2
SRGN ALB 25361965 interaction type N/A PTMCode2
ALB SRGN 25361965 interaction type N/A PTMCode2
SRGN PF4 25361965 interaction type N/A PTMCode2
PF4 SRGN 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FHL3 SRGN 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SGTA SRGN 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
SRGN CD44 14525934 25348397 27898060 9334256 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SRGN PF4 14525934 25348397 8613703 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SRGN CCL3 14525934 25348397 8613703 N/A experimental interaction detection,in vivo ComPPI,HPRD
SRGN UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
SRGN ALB 14525934 25348397 27898060 4062880 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SRGN GZMB 10228010 11911826 12388539 14525934 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction ComPPI,HPRD,IntAct,OmniPath
SRGN PSRC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRGN BAG6 25348397 N/A physical interaction ComPPI
SRGN CEP70 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRGN UBR4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRGN UBQLN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SRGN ZFC3H1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SRGN PRF1 11911826 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SRGN CRELD2 21900206 24234451 25348397 physical association two hybrid ComPPI,IntAct
SRGN VCAN 23601700 24234451 25348397 physical association zymography,comigration in gel electrophoresis ComPPI,IntAct
SRGN MMP9 23601700 24234451 25348397 N/A zymography ComPPI,IntAct
SRGN SGTB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRGN NCALD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRGN UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRGN PEX12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00008BCFD4 SRGN 27087310 direct interaction,inhibition N/A NPInter

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