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GENE：TFPI2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TFPI2
FullNmae tissue factor pathway inhibitor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11761
EnsembleID ENSG00000105825
Uniprot P48307

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TFPI2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TFPI2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TFPI2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TFPI2 GO:0004867,GO:0005201,GO:0005615,GO:0007596,GO:0031012,GO:0071498

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TFPI2 RELA 12208876 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
FOXA1 TFPI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TFPI2 12757776 trascriptional regulation,stimulation inferred by curator TFlink
KLF6 TFPI2 18053161 trascriptional regulation,stimulation inferred by curator TFlink
NFIC TFPI2 12757776 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 TFPI2 12757776 trascriptional regulation,stimulation inferred by curator TFlink
SP1 TFPI2 12446683 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 TFPI2 12446683 trascriptional regulation,stimulation inferred by curator TFlink
JUN TFPI2 N/A trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 TFPI2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005D986D TFPI2 21224345 rna interference,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00005D986D TFPI2 21224345 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
TFPI2 KLKB1 25361965 interaction type N/A PTMCode2
KLKB1 TFPI2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SKIL TFPI2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMURF2 TFPI2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PLG TFPI2 14525934 25348397 8555184 N/A experimental interaction detection,in vitro ComPPI,HPRD
TFPI2 KLKB1 14525934 25348397 8555184 N/A experimental interaction detection,in vitro ComPPI,HPRD
TFPI2 F11 14525934 25348397 8555184 N/A experimental interaction detection,in vitro ComPPI,HPRD

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