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GENE：FNIP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FNIP2
FullNmae folliculin interacting protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29280
EnsembleID ENSG00000052795
Uniprot Q9P278

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FNIP2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FNIP2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FNIP2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FNIP2 GO:0000122,GO:0001932,GO:0005515,GO:0005737,GO:0005737,GO:0005765,GO:0005829,GO:0006468,GO:0008630,GO:0031334,GO:0033138,GO:0034451,GO:0042030,GO:0042030,GO:0051087,GO:0051087,GO:1904263,GO:1990877

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FNIP2 hsa:57600 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR FNIP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 FNIP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FNIP2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 FNIP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 FNIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 FNIP2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005E6F45 FNIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 FNIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSP90AA1 FNIP2 25348397 N/A physical interaction ComPPI
STIP1 FNIP2 25348397 N/A physical interaction ComPPI
HSPA1A FNIP2 25348397 N/A physical interaction ComPPI
HSPA1B FNIP2 25348397 N/A physical interaction ComPPI
PTGES3 FNIP2 25348397 N/A physical interaction ComPPI
LAMTOR3 FNIP2 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
GABARAP FNIP2 25348397 N/A physical interaction ComPPI
NR3C1 FNIP2 25348397 N/A physical interaction ComPPI
CDC37 FNIP2 25348397 N/A physical interaction ComPPI
BRAF FNIP2 25348397 N/A physical interaction ComPPI
CDK4 FNIP2 25348397 N/A physical interaction ComPPI
FLCN FNIP2 25348397 N/A physical interaction ComPPI

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