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GENE：UBE2C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2C
FullNmae ubiquitin conjugating enzyme E2 C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15937
EnsembleID ENSG00000175063
Uniprot O00762

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2C mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBE2C autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2C GO:0000151,GO:0000209,GO:0004842,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005680,GO:0005829,GO:0005829,GO:0005886,GO:0006511,GO:0010458,GO:0010994,GO:0016567,GO:0030071,GO:0031145,GO:0031145,GO:0031145,GO:0031536,GO:0044389,GO:0045842,GO:0051301,GO:0061630,GO:0061631,GO:0061631,GO:0070936,GO:0070979,GO:1904668

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2C hsa:11065 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRIM23 UBE2C 20724660 23180781 ubiquitination reaction enzymatic study InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 UBE2C 17671431 18971253 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
ETS1 UBE2C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UBE2C 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC UBE2C 12747840 22170434 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UBE2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBE2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBE2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MED1 UBE2C 21556051 trascriptional regulation,stimulation inferred by curator TFlink
MBD4 UBE2C 21556051 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 UBE2C 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000821E0 UBE2C 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002B7450 UBE2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 UBE2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F UBE2C 23622248 25416803 25760688 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clash,miRNA interference luciferase reporter assay TarBase
URS00002075FA UBE2C 23622248 25416803 25760688 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clash,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
UBE2C ANAPC11 25361965 interaction type N/A PTMCode2
ANAPC11 UBE2C 25361965 interaction type N/A PTMCode2
CDC20 UBE2C 25361965 interaction type N/A PTMCode2
UBE2C CDC20 25361965 interaction type N/A PTMCode2
BUB1B UBE2C 25361965 interaction type N/A PTMCode2
UBE2C BUB1B 25361965 interaction type N/A PTMCode2
ANAPC2 UBE2C 25361965 interaction type N/A PTMCode2
UBE2C ANAPC2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TRIM21 UBE2C 25348397 N/A physical interaction ComPPI
UBASH3B UBE2C 25348397 N/A physical interaction ComPPI
ZNRD2 UBE2C 25348397 N/A physical interaction ComPPI
BAG3 UBE2C 25348397 N/A physical interaction ComPPI
PSMC6 UBE2C 25348397 N/A physical interaction ComPPI
RNF7 UBE2C 25348397 N/A physical interaction ComPPI
FZR1 UBE2C 25348397 N/A physical interaction ComPPI
UBB UBE2C 25348397 N/A physical interaction,comigration in sds page ComPPI
UBC UBE2C 25348397 N/A physical interaction,physical interaction,comigration in sds page ComPPI
RPS27A UBE2C 25348397 N/A physical interaction,comigration in sds page ComPPI
UBA52 UBE2C 25348397 N/A physical interaction,comigration in sds page ComPPI
PVR UBE2C 25348397 N/A physical interaction ComPPI
POLM UBE2C 25348397 N/A physical interaction ComPPI
PSMA5 UBE2C 25348397 N/A physical interaction ComPPI
TRIP6 UBE2C 25348397 N/A physical interaction ComPPI
TRIM29 UBE2C 25348397 N/A physical interaction ComPPI
RELA UBE2C 25348397 N/A physical interaction ComPPI
RANBP9 UBE2C 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2B UBE2C 25348397 N/A physical interaction ComPPI
RAG1 UBE2C 25348397 N/A physical interaction ComPPI
MAPK7 UBE2C 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZRANB2 UBE2C 25348397 N/A physical interaction ComPPI
CDC20 UBE2C 25348397 N/A physical interaction ComPPI
TRIM28 UBE2C 25348397 N/A physical interaction ComPPI
YAP1 UBE2C 25348397 N/A physical interaction ComPPI
UBQLN4 UBE2C 25348397 N/A physical interaction ComPPI
DTX1 UBE2C 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TNNC1 UBE2C 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PRKN UBE2C 25348397 N/A physical interaction ComPPI
PSMD4 UBE2C 25348397 N/A physical interaction ComPPI
UBE2D3 UBE2C 25348397 N/A physical interaction ComPPI
UBA1 UBE2C 25348397 N/A physical interaction ComPPI
PCMT1 UBE2C 25348397 N/A physical interaction ComPPI
BUB1B UBE2C 25348397 N/A physical interaction ComPPI
PSMB5 UBE2C 25348397 N/A physical interaction ComPPI
UBE4B UBE2C 25348397 N/A physical interaction ComPPI
ELAVL1 UBE2C 25348397 N/A physical interaction ComPPI
UBQLN1 UBE2C 25348397 N/A physical interaction ComPPI
RNF216 UBE2C 25348397 N/A physical interaction ComPPI
MAD2L1 UBE2C 25348397 N/A physical interaction ComPPI
UBE2V1 UBE2C 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
ANAPC2 UBE2C 11739784 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
UBE2C ENO2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBE2C ANAPC11 11739784 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
UBE2C UBE3D 25348397 N/A physical interaction ComPPI
UBE2C CKAP2 25348397 N/A physical interaction ComPPI
UBE2C USP34 25348397 N/A physical interaction ComPPI
UBE2C AHCYL1 25348397 N/A physical interaction ComPPI
UBE2C ATP6V1F 25348397 N/A physical interaction ComPPI
UBE2C PPM1G 25348397 N/A physical interaction ComPPI
UBE2C USP9X 25348397 N/A physical interaction ComPPI
UBE2C TTLL12 25348397 N/A physical interaction ComPPI
UBE2C SEC24A 25348397 N/A physical interaction ComPPI
UBE2C UBXN7 25348397 N/A physical interaction ComPPI
UBE2C TTC9C 25348397 N/A physical interaction ComPPI
UBE2C ZFYVE19 25348397 N/A physical interaction ComPPI
UBE2C UNK 25348397 N/A physical interaction ComPPI
UBE2C TYMS 25348397 N/A physical interaction ComPPI
UBE2C UBXN1 25348397 N/A physical interaction ComPPI
UBE2C CXCR1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2C PCGF3 19549727 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2C KLHL2 25348397 N/A physical interaction ComPPI
UBE2C PSMC2 25348397 N/A physical interaction ComPPI
UBE2C NAXD 25348397 N/A physical interaction ComPPI
UBE2C TAGLN2 25348397 N/A physical interaction ComPPI
UBE2C UBE2S 25348397 N/A physical interaction ComPPI
EBNA1BP2 UBE2C 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
ATP6V1B2 UBE2C 25348397 N/A physical interaction ComPPI
UBE2C UBE2C 11927573 14525934 N/A experimental interaction detection HPRD
IKBKG UBE2C 20098747 27898060 N/A N/A OmniPath

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