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GENE：ENDOG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ENDOG
FullNmae endonuclease G
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3346
EnsembleID ENSG00000167136
Uniprot Q14249

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ENDOG autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ENDOG apoptosis 33779488 ENDOG (endonuclease G), a mitochondrial endonuclease, is known to participate in apoptosis and paternal mitochondria elimination. retulator signature

Go Annotation:

GeneSymbol Go id
ENDOG GO:0000014,GO:0000287,GO:0001701,GO:0003676,GO:0004520,GO:0004521,GO:0005515,GO:0005634,GO:0005739,GO:0005743,GO:0006309,GO:0006310,GO:0006974,GO:0010508,GO:0032007,GO:0032043,GO:0034612,GO:0042803,GO:0043065,GO:0046677,GO:0090297

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ENDOG hsa:2021 path:hsa04210 Apoptosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ENDOG 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ENDOG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ENDOG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ENDOG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ENDOG 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 ENDOG 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
FEN1 ENDOG 25361965 interaction type N/A PTMCode2
ENDOG FEN1 25361965 interaction type N/A PTMCode2
AIFM1 ENDOG 25361965 interaction type N/A PTMCode2
ENDOG AIFM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSPA8 ENDOG 25348397 N/A physical interaction ComPPI
ZNRD2 ENDOG 25348397 N/A physical interaction ComPPI
PCGF2 ENDOG 25348397 N/A physical interaction ComPPI
EVL ENDOG 25348397 N/A physical interaction ComPPI
FEN1 ENDOG 25348397 N/A physical interaction ComPPI
EPHA8 ENDOG 25348397 N/A physical interaction ComPPI
GRK6 ENDOG 25348397 N/A physical interaction ComPPI
HSPA4 ENDOG 16133872 23764847 25348397 27898060 N/A physical interaction ComPPI,OmniPath
NFYC ENDOG 25348397 N/A physical interaction ComPPI
BAG4 ENDOG 25348397 N/A physical interaction ComPPI
BIRC2 ENDOG 25348397 N/A physical interaction ComPPI
STUB1 ENDOG 25348397 N/A physical interaction ComPPI
DNAJA1 ENDOG 25348397 N/A physical interaction ComPPI
AURKB ENDOG 25348397 N/A physical interaction ComPPI
DKC1 ENDOG 25348397 N/A physical interaction ComPPI
AIFM1 ENDOG 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
COX4I1 ENDOG 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PLGRKT ENDOG 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ITLN1 ENDOG 25348397 N/A physical interaction ComPPI
TPM1 ENDOG 25348397 N/A physical interaction ComPPI
SFXN1 ENDOG 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PRKACG ENDOG 25348397 N/A physical interaction ComPPI
PTCH1 ENDOG 25348397 N/A physical interaction ComPPI
ENDOG DNAJA4 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
ENDOG ITLN2 25348397 N/A physical interaction ComPPI
ENDOG CPA4 25348397 N/A physical interaction ComPPI
ENDOG COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ENDOG SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TH ENDOG 25139236 27898060 N/A N/A OmniPath
BID ENDOG 11452314 11753562 27898060 stimulant N/A OmniPath
BAK1 ENDOG 12232790 27898060 stimulant N/A OmniPath
BAX ENDOG 12232790 27898060 stimulant N/A OmniPath

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