Gene Information gene info

GENE:DAG1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DAG1
FullNmae dystroglycan 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2666
EnsembleID ENSG00000173402
Uniprot Q14118

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DAG1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DAG1 GO:0001618,GO:0001954,GO:0002009,GO:0002011,GO:0002162,GO:0003007,GO:0003779,GO:0005509,GO:0005515,GO:0005576,GO:0005576,GO:0005604,GO:0005604,GO:0005615,GO:0005615,GO:0005615,GO:0005654,GO:0005737,GO:0005788,GO:0005796,GO:0005829,GO:0005856,GO:0005886,GO:0005886,GO:0005912,GO:0005925,GO:0005925,GO:0006509,GO:0007411,GO:0008307,GO:0009897,GO:0010470,GO:0010717,GO:0014850,GO:0014894,GO:0015031,GO:0015631,GO:0016010,GO:0016011,GO:0016020,GO:0016203,GO:0016323,GO:0016340,GO:0016476,GO:0017166,GO:0021675,GO:0021682,GO:0022011,GO:0030027,GO:0030175,GO:0030336,GO:0031103,GO:0031643,GO:0033268,GO:0034399,GO:0034453,GO:0042169,GO:0042383,GO:0043034,GO:0043231,GO:0043236,GO:0043237,GO:0043403,GO:0043409,GO:0043434,GO:0044853,GO:0044877,GO:0045211,GO:0046718,GO:0048167,GO:0048714,GO:0050807,GO:0051393,GO:0051898,GO:0060055,GO:0060441,GO:0060445,GO:0062023,GO:0070062,GO:0070938,GO:0071260,GO:0071397,GO:0071679,GO:0071711,GO:0098684,GO:0098696,GO:0098942,GO:0098978,GO:0098982,GO:0099524,GO:1904261

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DAG1 hsa:1605 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)
DAG1 hsa:1605 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
DAG1 hsa:1605 path:hsa05412 Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)
DAG1 hsa:1605 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)
DAG1 hsa:1605 path:hsa05416 Viral myocarditis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DAG1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DAG1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DAG1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C DAG1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DAG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000076995 DAG1 21169019 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS0000338542 DAG1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 DAG1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000BE495 DAG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E DAG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 DAG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001E0AEA DAG1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NCK1 DAG1 25361965 interaction type N/A PTMCode2
DAG1 NCK1 25361965 interaction type N/A PTMCode2
LAMA5 DAG1 25361965 interaction type N/A PTMCode2
DAG1 LAMA5 25361965 interaction type N/A PTMCode2
DAG1 BGN 25361965 interaction type N/A PTMCode2
BGN DAG1 25361965 interaction type N/A PTMCode2
DAG1 SGCD 25361965 interaction type N/A PTMCode2
SGCD DAG1 25361965 interaction type N/A PTMCode2
DAG1 GRB2 25361965 interaction type N/A PTMCode2
GRB2 DAG1 25361965 interaction type N/A PTMCode2
DAG1 CAV1 25361965 interaction type N/A PTMCode2
CAV1 DAG1 25361965 interaction type N/A PTMCode2
DAG1 SRC 25361965 interaction type N/A PTMCode2
SRC DAG1 25361965 interaction type N/A PTMCode2
DAG1 DMD 25361965 interaction type N/A PTMCode2
DMD DAG1 25361965 interaction type N/A PTMCode2
DAG1 FYN 25361965 interaction type N/A PTMCode2
FYN DAG1 25361965 interaction type N/A PTMCode2
DAG1 AGRN 25361965 interaction type N/A PTMCode2
AGRN DAG1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SH3KBP1 DAG1 25348397 N/A physical interaction ComPPI
AGR3 DAG1 25348397 N/A two hybrid,physical interaction ComPPI
AGR2 DAG1 25348397 N/A physical interaction ComPPI
PPP1CB DAG1 25348397 N/A physical interaction ComPPI
LGALS9C DAG1 25348397 N/A physical interaction ComPPI
PIK3R1 DAG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SRC DAG1 17474147 24234451 25348397 physical association peptide array,physical interaction,in vitro,in vivo ComPPI,IntAct
SHC1 DAG1 25348397 N/A physical interaction,in vivo ComPPI
NCK1 DAG1 17474147 24234451 25348397 physical association peptide array,physical interaction ComPPI,IntAct
GRB2 DAG1 10903901 17474147 24234451 25348397 27898060 7744812 physical association peptide array,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
ITGB1 DAG1 25348397 N/A physical interaction ComPPI
WWP1 DAG1 25348397 N/A in vitro ComPPI
ACTN1 DAG1 25348397 N/A physical interaction ComPPI
BGN DAG1 25348397 N/A in vitro,in vivo ComPPI
CDH1 DAG1 25348397 N/A physical interaction ComPPI
CDH5 DAG1 25348397 N/A physical interaction ComPPI
WWP2 DAG1 25348397 N/A in vitro ComPPI
TLN1 DAG1 25348397 N/A physical interaction ComPPI
MAGI1 DAG1 25348397 N/A in vitro ComPPI
CAV1 DAG1 25348397 N/A physical interaction ComPPI
MAP2 DAG1 25348397 N/A physical interaction ComPPI
VCL DAG1 25348397 N/A physical interaction ComPPI
WWC1 DAG1 25348397 N/A physical interaction ComPPI
TNF DAG1 25348397 N/A physical interaction ComPPI
UTRN DAG1 10767429 10769203 24234451 25348397 27898060 association cross-linking study,phage display,pull down,physical interaction,in vitro ComPPI,IntAct,OmniPath
CSK DAG1 25348397 N/A physical interaction ComPPI
CAV3 DAG1 10988290 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
DAG1 LAMA1 25348397 N/A in vitro,in vivo ComPPI
DAG1 LAMA2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
DAG1 DRP2 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
DAG1 LAMA5 24234451 25348397 association cross-linking study,physical interaction,in vitro ComPPI,IntAct
DAG1 RAPSN 11342559 25348397 27898060 7619516 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
DAG1 DMD 10355629 10932245 22937058 24234451 25348397 27898060 7592992 N/A pull down,x-ray crystallography,physical interaction ComPPI,IntAct,OmniPath
DAG1 PRX 25348397 N/A physical interaction ComPPI
DAG1 FYN 17474147 24234451 25348397 physical association peptide array,physical interaction ComPPI,IntAct
DAG1 AGRN 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
DAG1 TUBA1A 25348397 N/A physical interaction ComPPI
DAG1 PTK2 25348397 N/A physical interaction ComPPI
DAG1 ELAVL1 25348397 N/A physical interaction ComPPI
DAG1 CORO7 25348397 N/A physical interaction ComPPI
DAG1 HLA-DPA1 25348397 N/A physical interaction ComPPI
DAG1 CEACAM21 25348397 N/A physical interaction ComPPI
DAG1 LGALS8 25348397 N/A physical interaction ComPPI
DAG1 LGALS9 25348397 N/A physical interaction ComPPI
DAG1 GINM1 25348397 N/A physical interaction ComPPI
DAG1 HTR3C 25348397 N/A physical interaction ComPPI
DAG1 CLIC4 25348397 N/A physical interaction ComPPI
DAG1 DNAJB1 25348397 N/A physical interaction ComPPI
DAG1 VPS45 25348397 N/A physical interaction ComPPI
DAG1 PCDHGA5 25348397 N/A physical interaction ComPPI
DAG1 PCDHGB4 25348397 N/A physical interaction ComPPI
DAG1 TCTN2 25348397 N/A physical interaction ComPPI
DAG1 PCDHB11 25348397 N/A physical interaction ComPPI
DAG1 PCDHAC2 25348397 N/A physical interaction ComPPI
DAG1 FKBP9 25348397 N/A physical interaction ComPPI
DAG1 TNFSF8 25348397 N/A physical interaction ComPPI
DAG1 IL13RA2 25348397 N/A physical interaction ComPPI
DAG1 TRIM25 25348397 N/A physical interaction ComPPI
DAG1 NCSTN 18942891 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DAG1 PSEN1 18942891 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DAG1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DAG1 DAG1 11423118 24234451 N/A x-ray crystallography,enzyme linked immunosorbent assay IntAct
DAG1 HSPA5 24234451 association cross-linking study IntAct
DAG1 CAT 24234451 association cross-linking study IntAct
DAG1 LCP1 24234451 association cross-linking study IntAct
DAG1 SGCB 24234451 association cross-linking study IntAct
DAG1 PSMB2 24234451 association cross-linking study IntAct
DAG1 RBBP4 24234451 association cross-linking study IntAct
DAG1 POF1B 24234451 association cross-linking study IntAct
DAG1 TPI1 24234451 association cross-linking study IntAct
DAG1 GPC1 24234451 association cross-linking study IntAct
DAG1 SLC3A2 24234451 association cross-linking study IntAct
DAG1 SGCD 24234451 association cross-linking study IntAct
DAG1 SGCE 24234451 association cross-linking study IntAct
DAG1 MDH1 24234451 association cross-linking study IntAct
DAG1 H4C1 24234451 association cross-linking study IntAct
DAG1 RPIA 24234451 association cross-linking study IntAct
DAG1 ABCC4 24234451 association cross-linking study IntAct
DAG1 GOT1 24234451 association cross-linking study IntAct
DAG1 GOT2 24234451 association cross-linking study IntAct
DAG1 PSMA2 24234451 association cross-linking study IntAct
DAG1 PSMB4 24234451 association cross-linking study IntAct
DAG1 LGALS7 24234451 association cross-linking study IntAct
DAG1 LAMB1 24234451 association cross-linking study IntAct
DAG1 AZGP1 24234451 association cross-linking study IntAct
DAG1 DTNB 24234451 association cross-linking study IntAct
DAG1 HARS1 24234451 association cross-linking study IntAct
DAG1 UBR7 24234451 association cross-linking study IntAct
DAG1 KIDINS220 24234451 association cross-linking study IntAct
DAG1 PDIA4 24234451 association cross-linking study IntAct
DAG1 SNTB2 24234451 association cross-linking study IntAct
SRC DAG1 11724572 12795607 17474147 27898060 inhibition,stimulant N/A OmniPath

Visualization