Gene Information gene info

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GENE：HSF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSF2
FullNmae heat shock transcription factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5225
EnsembleID ENSG00000025156
Uniprot Q03933

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSF2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HSF2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HSF2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSF2 GO:0000785,GO:0000977,GO:0000978,GO:0000978,GO:0000981,GO:0001162,GO:0001228,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006357,GO:0007283,GO:0042802,GO:0045944,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR HSF2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HSF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP63 HSF2 17521434 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 HSF2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HSF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HSF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HSF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HSF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HSF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 HSF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 HSF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E HSF2 20724452 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000035CC3E HSF2 20724452 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000003ABC4 HSF2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 HSF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB HSF2 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 HSF2 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000075AB0E HSF2 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000031602A HSF2 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000075B538 HSF2 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS0000013DD8 HSF2 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MOS HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
UBE2I HSF2 11278381 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HSPA8 HSF2 25348397 N/A physical interaction ComPPI
TMSB4X HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG3 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HSPBP1 HSF2 25348397 N/A physical interaction ComPPI
NUP62 HSF2 14525934 24234451 25348397 25416956 27898060 9367915 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct,OmniPath
MCM5 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PCGF2 HSF2 25348397 N/A physical interaction ComPPI
PICK1 HSF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBBP6 HSF2 25348397 N/A physical interaction ComPPI
FZR1 HSF2 25348397 N/A physical interaction ComPPI
CUL3 HSF2 19768582 25348397 27898060 N/A physical interaction ComPPI,OmniPath
IRS4 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PRMT1 HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG1 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
THOC5 HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TPM3 HSF2 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
SUMO2 HSF2 14525934 16428449 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SUMO3 HSF2 14525934 16428449 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CDC20 HSF2 25348397 N/A physical interaction ComPPI
URI1 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BAG4 HSF2 24234451 25036637 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
NCBP1 HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD50 HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STUB1 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PATJ HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SRSF7 HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCAPG HSF2 14525934 15662014 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
HUS1B HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
USP49 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BAG2 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HSF1 HSF2 12813038 14525934 24234451 25036637 25348397 26186194 26496610 26727490 27898060 association,physical association anti tag coimmunoprecipitation,cross-linking study,experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
PIWIL1 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NLRP12 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ERCC2 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CDC27 HSF2 25348397 N/A physical interaction ComPPI
WDR5 HSF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRCC HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CEP76 HSF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SIRT6 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MTUS2 HSF2 25348397 N/A physical interaction ComPPI
HSF2 ASAH1 25348397 N/A physical interaction ComPPI
HSF2 ECI2 25348397 N/A physical interaction ComPPI
HSF2 ANKLE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF2 CHTOP 25348397 N/A physical interaction ComPPI
HSF2 OTUD4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF2 TFDP3 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HSF4 HSF2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG5 HSF2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PPP2R1A HSF2 10224043 14525934 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
UBE2I HSF2 11278381 18211895 27898060 inhibition N/A OmniPath
PCGF2 HSF2 18211895 27898060 inhibition N/A OmniPath

Visualization










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