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GENE：PJA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PJA2
FullNmae praja ring finger ubiquitin ligase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17481
EnsembleID ENSG00000198961
Uniprot O43164

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PJA2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PJA2 GO:0000139,GO:0004842,GO:0005515,GO:0005737,GO:0005789,GO:0005813,GO:0005886,GO:0006954,GO:0007616,GO:0010738,GO:0010738,GO:0014069,GO:0016567,GO:0016567,GO:0016567,GO:0034137,GO:0034236,GO:0034237,GO:0034451,GO:0036064,GO:0043030,GO:0043161,GO:0045087,GO:0045111,GO:0046330,GO:0046872,GO:0061630,GO:1900745

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PJA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PJA2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PJA2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A PJA2 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
FOXA1 PJA2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP63 PJA2 17521434 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PJA2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PJA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PJA2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001B341F PJA2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000017EA6A PJA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000006372A PJA2 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA PJA2 22135298 phosphorylation N/A PhosphoSite
PJA2 MAGED1 25361965 interaction type N/A PTMCode2
MAGED1 PJA2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2D1 PJA2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D4 PJA2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EGLN3 PJA2 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
UBE2D2 PJA2 12036302 14525934 19690564 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
CUL3 PJA2 25348397 N/A physical interaction ComPPI
PRKAR1A PJA2 25348397 N/A physical interaction ComPPI
UBE2N PJA2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FAF1 PJA2 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KSR2 PJA2 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PRKAR2A PJA2 24083380 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CFTR PJA2 25348397 N/A physical interaction ComPPI
XPO1 PJA2 25348397 N/A physical interaction ComPPI
MAGED1 PJA2 11959851 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PJA2 USP46 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PJA2 UBE2D3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PJA2 UBE2J1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PJA2 UBE2L6 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PJA2 UBE2W 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PJA2 UBXN7 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PJA2 FAF2 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PJA2 UBXN1 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PJA2 ELAVL1 25348397 N/A physical interaction ComPPI
PJA2 CEP192 25348397 N/A physical interaction ComPPI
PJA2 MAGED2 25348397 N/A physical interaction ComPPI
PJA2 AP2M1 25348397 N/A physical interaction ComPPI
PJA2 UNK 25348397 N/A physical interaction ComPPI
PJA2 KIAA0753 25348397 N/A physical interaction ComPPI
PJA2 FBXL17 25348397 N/A physical interaction ComPPI
PJA2 KSR1 25348397 N/A physical interaction ComPPI
PJA2 ARHGAP36 25348397 N/A physical interaction ComPPI
PJA2 IQCN 25348397 N/A physical interaction ComPPI
PJA2 MFHAS1 25348397 N/A physical interaction ComPPI
PJA2 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TNIP1 PJA2 24234451 30561431 association virotrap IntAct
PRKACA PJA2 21423175 27898060 N/A N/A OmniPath

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