Gene Information gene info

  1. Home

GENE：ATF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATF1
FullNmae activating transcription factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:783
EnsembleID ENSG00000123268
Uniprot P18846

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATF1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATF1 GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006357,GO:0006357,GO:0006357,GO:0010976,GO:0014074,GO:0019933,GO:0032025,GO:0042802,GO:0044877,GO:0045740,GO:0045944,GO:0065003,GO:0090575,GO:1990589,GO:1990590

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATF1 hsa:466 path:hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)
ATF1 hsa:466 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATF4 ATF1 23180781 9417115 physical association electrophoretic mobility supershift assay InnateDB
CIITA ATF1 12391222 23180781 physical association electrophoretic mobility supershift assay InnateDB
ATF1 IFNG 18641343 23180781 physical association electrophoretic mobility supershift assay InnateDB
FOS ATF1 18641343 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATF1 KIR3DL1 16818466 23180781 physical association electrophoretic mobility supershift assay InnateDB
ATF1 CXCR4 17130833 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATF1 KIR2DL4 22467658 23180781 physical association electrophoretic mobility supershift assay InnateDB
ATF1 YWHAZ 23180781 24690670 physical association anti tag coimmunoprecipitation,pull down,electrophoretic mobility supershift assay InnateDB
RPS6KA5 ATF1 11018520 11909979 18988627 23331499 stimulation N/A SignaLink,SignaLink
SMAD4 ATF1 10480932 23331499 stimulation N/A SignaLink
RPS6KA4 ATF1 11909979 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 ATF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ATF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EWSR1 ATF1 9569031 trascriptional regulation,stimulation inferred by curator TFlink
PIAS3 ATF1 17565989 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 ATF1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 ATF1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001CC864 ATF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC379 ATF1 23249749 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000065D58 ATF1 25416803 28259977 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 ATF1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK3 ATF1 22135298 phosphorylation N/A PhosphoSite
CSNK1A1 ATF1 22135298 phosphorylation N/A PhosphoSite
RPS6KA5 ATF1 22135298 phosphorylation N/A PhosphoSite
ATF1 CSNK2A1 25361965 interaction type N/A PTMCode2
SPI1 ATF1 25361965 interaction type N/A PTMCode2
ATF1 SPI1 25361965 interaction type N/A PTMCode2
ATF1 RPS6KA4 25361965 interaction type N/A PTMCode2
RPS6KA4 ATF1 25361965 interaction type N/A PTMCode2
ATF1 JUN 25361965 interaction type N/A PTMCode2
JUN ATF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TFAP4 ATF1 25348397 N/A physical interaction ComPPI
HSPA8 ATF1 25348397 N/A physical interaction ComPPI
EDF1 ATF1 10567391 14525934 25348397 N/A experimental interaction detection,pull down,in vitro ComPPI,HPRD
TP53BP1 ATF1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
GABPB1 ATF1 10585419 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JUNB ATF1 25348397 N/A physical interaction ComPPI
NFATC1 ATF1 24234451 25348397 25609649 association,physical association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
SPI1 ATF1 14525934 25348397 7730336 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
JUN ATF1 14525934 24234451 25348397 25609649 8570175 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
CREBBP ATF1 14525934 25348397 8663317 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FOSL2 ATF1 25348397 N/A physical interaction ComPPI
PRKACA ATF1 14525934 25348397 9016641 N/A experimental interaction detection,in vitro ComPPI,HPRD
RPS6KA4 ATF1 11909979 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CSNK2A1 ATF1 14525934 25348397 9685505 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CAMK2G ATF1 25348397 N/A in vitro,in vivo ComPPI
CSNK2A2 ATF1 14525934 25348397 9685505 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RPS6KA5 ATF1 11018520 11909979 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GABPA ATF1 10585419 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAPKAPK2 ATF1 25348397 N/A physical interaction ComPPI
CAMK1 ATF1 14525934 25348397 8384217 N/A experimental interaction detection,in vitro ComPPI,HPRD
TUFT1 ATF1 25348397 N/A physical interaction ComPPI
BACH1 ATF1 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
MAPKAPK3 ATF1 25348397 N/A physical interaction ComPPI
ESR1 ATF1 21217774 24234451 25348397 N/A phage display ComPPI,IntAct
DNMT3L ATF1 25348397 N/A physical interaction ComPPI
BRCA1 ATF1 10945975 14525934 25348397 27898060 N/A affinity chromatography technology,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
ATF1 CREB1 14525934 1655749 20102225 24234451 25348397 25609649 8384217 association,physical association experimental interaction detection,peptide array,pull down,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
ATF1 HNF1B 14525934 25348397 9671480 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ATF1 CREM 12805554 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ATF1 CSNK2B 25348397 N/A physical interaction ComPPI
ATF1 CAMK2A 25348397 N/A physical interaction ComPPI
ATF1 SRA1 25348397 N/A physical interaction ComPPI
ATF1 CACNG2 25348397 N/A physical interaction ComPPI
ATF1 TRPV5 25348397 N/A physical interaction ComPPI
ATF1 MIA2 25348397 N/A physical interaction ComPPI
ATF1 ARHGAP22 25348397 N/A physical interaction ComPPI
ATF1 CCDC97 25348397 N/A physical interaction ComPPI
ATF1 IDO2 25348397 N/A physical interaction ComPPI
ATF1 CREBRF 25348397 N/A physical interaction ComPPI
ATF1 CSGALNACT2 25348397 N/A physical interaction ComPPI
ATF1 ARIH1 25348397 N/A physical interaction ComPPI
ATF1 SSH1 25348397 N/A physical interaction ComPPI
NFIL3 ATF1 20102225 24234451 25348397 N/A peptide array,physical interaction ComPPI,IntAct
ATF2 ATF1 24234451 25348397 25609649 physical association pull down,physical interaction ComPPI,IntAct
ATF1 ATF1 14525934 20102225 21045134 24234451 9016641 N/A cosedimentation in solution,experimental interaction detection,peptide array HPRD,IntAct
PRKACA ATF1 20068231 27898060 8663317 9016641 N/A N/A OmniPath
PRKCE ATF1 11335727 12414794 18794154 27898060 9685505 N/A N/A OmniPath
CSNK1A1 ATF1 27898060 8414969 8600455 N/A N/A OmniPath
RPS6KA5 ATF1 11018520 11909979 12414794 18794154 18813292 20068231 27898060 8663317 stimulant N/A OmniPath
ATF1 IL10 20154735 27898060 stimulant N/A OmniPath
ATF1 ARNT2 12527906 27898060 stimulant N/A OmniPath
ATF1 ATM 12527906 27898060 stimulant N/A OmniPath
ATF1 SH3RF1 12527906 27898060 stimulant N/A OmniPath
ATF1 CCDC65 12527906 27898060 stimulant N/A OmniPath
ATF1 NKX6-1 12527906 27898060 stimulant N/A OmniPath
RPS6KA4 ATF1 11909979 18813292 20068231 20626350 27898060 8663317 stimulant N/A OmniPath
ATF1 GOLPH3 12527906 27898060 stimulant N/A OmniPath
CSNK2A1 ATF1 18452278 18669648 20730097 27898060 8663317 9685505 inhibition,stimulant N/A OmniPath
SMAD4 ATF1 10480932 27898060 stimulant N/A OmniPath
HIPK2 ATF1 18669648 19690332 20980392 27898060 N/A N/A OmniPath
PPP2R5C ATF1 20730097 27898060 stimulant N/A OmniPath
CAMK1 ATF1 20068231 27898060 8384217 8663317 N/A N/A OmniPath
CAMK2G ATF1 20068231 27898060 8663317 N/A N/A OmniPath
HNF1B ATF1 27898060 9671480 stimulant N/A OmniPath
CDK3 ATF1 18794154 27898060 stimulant N/A OmniPath

Visualization










  Return