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GENE：IL13RA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL13RA2
FullNmae interleukin 13 receptor subunit alpha 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5975
EnsembleID ENSG00000123496
Uniprot Q14627

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL13RA2 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
IL13RA2 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
IL13RA2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IL13RA2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IL13RA2 GO:0002638,GO:0004896,GO:0004896,GO:0005515,GO:0005576,GO:0005615,GO:0009897,GO:0016064,GO:0019221,GO:0019955,GO:0043235,GO:0043305

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL13RA2 hsa:3598 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IL13RA2 hsa:3598 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL13 IL13RA2 12223527 12401408 14610620 14657224 14985454 15099563 18250477 18451175 20184663 21097505 23180781 23331499 26192618 26755705 8663118 9535722 stimulation,association,physical association protein cross-linking with a bifunctional reagent,saturation binding ACSN,InnateDB,SignaLink,SignaLink
STAT6 IL13RA2 10485906 12223527 12244147 14610620 15634881 16327802 23124025 24204259 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
YBX1 IL13RA2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA IL13RA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IL13RA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 IL13RA2 N/A trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 IL13RA2 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A IL13RA2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 IL13RA2 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 IL13RA2 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
LGALS3 IL13RA2 24234451 25348397 29427412 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
BRMS1 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SEMA4C IL13RA2 25348397 N/A physical interaction ComPPI
TSHZ3 IL13RA2 25348397 N/A physical interaction ComPPI
LARP4B IL13RA2 25348397 N/A physical interaction ComPPI
SIK2 IL13RA2 25348397 N/A physical interaction ComPPI
ERBB2 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PAX2 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PIK3CA IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPRF IL13RA2 25348397 N/A physical interaction ComPPI
JAK1 IL13RA2 25348397 N/A physical interaction ComPPI
RAB3B IL13RA2 25348397 N/A physical interaction ComPPI
CASP8 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPRS IL13RA2 25348397 N/A physical interaction ComPPI
ERF IL13RA2 25348397 N/A physical interaction ComPPI
MAN1A2 IL13RA2 25348397 N/A physical interaction ComPPI
RNASEL IL13RA2 25348397 N/A physical interaction ComPPI
IPO11 IL13RA2 25348397 N/A physical interaction ComPPI
CHEK1 IL13RA2 25348397 N/A physical interaction ComPPI
DAG1 IL13RA2 25348397 N/A physical interaction ComPPI
MELK IL13RA2 25348397 N/A physical interaction ComPPI
BAG4 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CAND1 IL13RA2 25348397 N/A physical interaction ComPPI
ANTXR1 IL13RA2 25348397 N/A physical interaction ComPPI
MAP2K7 IL13RA2 25348397 N/A physical interaction ComPPI
NOTCH2 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SYMPK IL13RA2 25348397 N/A physical interaction ComPPI
RFC5 IL13RA2 25348397 N/A physical interaction ComPPI
RB1CC1 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KIRREL1 IL13RA2 25348397 N/A physical interaction ComPPI
RFC4 IL13RA2 25348397 N/A physical interaction ComPPI
ORC5 IL13RA2 25348397 N/A physical interaction ComPPI
ESR2 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AKT1 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TNFSF9 IL13RA2 25348397 N/A physical interaction ComPPI
XRCC3 IL13RA2 25348397 N/A physical interaction ComPPI
NEK6 IL13RA2 25348397 N/A physical interaction ComPPI
PRKD2 IL13RA2 25348397 N/A physical interaction ComPPI
TTK IL13RA2 25348397 N/A physical interaction ComPPI
SH3BP4 IL13RA2 25348397 N/A physical interaction ComPPI
NEK7 IL13RA2 25348397 N/A physical interaction ComPPI
RPTOR IL13RA2 25348397 N/A physical interaction ComPPI
POP4 IL13RA2 25348397 N/A physical interaction ComPPI
IGF1R IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
B4GALT1 IL13RA2 25348397 N/A physical interaction ComPPI
RICTOR IL13RA2 25348397 N/A physical interaction ComPPI
ULBP3 IL13RA2 25348397 N/A physical interaction ComPPI
HOXD13 IL13RA2 25348397 N/A physical interaction ComPPI
ST3GAL2 IL13RA2 25348397 N/A physical interaction ComPPI
ADCK1 IL13RA2 25348397 N/A physical interaction ComPPI
B4GALT3 IL13RA2 25348397 N/A physical interaction ComPPI
MTFR1 IL13RA2 25348397 N/A physical interaction ComPPI
DNAAF5 IL13RA2 25348397 N/A physical interaction ComPPI
COMMD3 IL13RA2 25348397 N/A physical interaction ComPPI
PALB2 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KNTC1 IL13RA2 25348397 N/A physical interaction ComPPI
LRFN1 IL13RA2 25348397 N/A physical interaction ComPPI
IL13 IL13RA2 11003391 14525934 20223216 24234451 25348397 27629921 physical association anti bait coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,molecular sieving,surface plasmon resonance,x-ray crystallography,physical interaction,biochemical,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
IL13RA2 IL4 14525934 25348397 27898060 9130652 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
IL13RA2 ENDOD1 25348397 N/A physical interaction ComPPI
IL13RA2 C17ORF80 25348397 N/A physical interaction ComPPI
IL13RA2 SLC25A23 25348397 N/A physical interaction ComPPI
IL13RA2 STOML1 25348397 N/A physical interaction ComPPI
IL13RA2 ZNF195 25348397 N/A physical interaction ComPPI
IL13RA2 SAMD1 25348397 N/A physical interaction ComPPI
IL13RA2 METTL15 25348397 N/A physical interaction ComPPI
IL13RA2 VPS26C 25348397 N/A physical interaction ComPPI
IL13RA2 TVP23C 25348397 N/A physical interaction ComPPI
IL13RA2 PHLDB3 25348397 N/A physical interaction ComPPI
IL13RA2 SDK2 25348397 N/A physical interaction ComPPI
IL13RA2 HSD17B11 25348397 N/A physical interaction ComPPI
IL13RA2 ZNHIT6 25348397 N/A physical interaction ComPPI
IL13RA2 SLC25A25 25348397 N/A physical interaction ComPPI
IL13RA2 PTPMT1 25348397 N/A physical interaction ComPPI
IL13RA2 ABHD14A 25348397 N/A physical interaction ComPPI
IL13RA2 GCN1 25348397 N/A physical interaction ComPPI
IL13RA2 INTS12 25348397 N/A physical interaction ComPPI
IL13RA2 GK 25348397 N/A physical interaction ComPPI
IL13RA2 B4GALT5 25348397 N/A physical interaction ComPPI
IL13RA2 MTO1 25348397 N/A physical interaction ComPPI
IL13RA2 PRORP 25348397 N/A physical interaction ComPPI
IL13RA2 HIP1R 25348397 N/A physical interaction ComPPI
IL13RA2 ZDHHC18 25348397 N/A physical interaction ComPPI
IL13RA2 NAMPT 25348397 N/A physical interaction ComPPI
IL13RA2 MYO19 25348397 N/A physical interaction ComPPI
IL13RA2 FAM207A 25348397 N/A physical interaction ComPPI
IL13RA2 SLC25A46 25348397 N/A physical interaction ComPPI
IL13RA2 RARS2 25348397 N/A physical interaction ComPPI
IL13RA2 GATB 25348397 N/A physical interaction ComPPI
IL13RA2 ARV1 25348397 N/A physical interaction ComPPI
IL13RA2 GUF1 25348397 N/A physical interaction ComPPI
IL13RA2 ECHDC1 25348397 N/A physical interaction ComPPI
IL13RA2 PALD1 25348397 N/A physical interaction ComPPI
IL13RA2 SGPL1 25348397 N/A physical interaction ComPPI
IL13RA2 UCKL1 25348397 N/A physical interaction ComPPI
IL13RA2 TMED4 25348397 N/A physical interaction ComPPI
IL13RA2 NOCT 25348397 N/A physical interaction ComPPI
IL13RA2 AHCTF1 25348397 N/A physical interaction ComPPI
IL13RA2 SENP1 25348397 N/A physical interaction ComPPI
IL13RA2 ALG5 25348397 N/A physical interaction ComPPI
IL13RA2 BDH1 25348397 N/A physical interaction ComPPI
IL13RA2 ATP12A 25348397 N/A physical interaction ComPPI
IL13RA2 INTS7 25348397 N/A physical interaction ComPPI
IL13RA2 MCU 25348397 N/A physical interaction ComPPI
IL13RA2 RBM15B 25348397 N/A physical interaction ComPPI
IL13RA2 CAPN8 25348397 N/A physical interaction ComPPI
IL13RA2 TM2D3 25348397 N/A physical interaction ComPPI
IL13RA2 PLPP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL13RA2 TMEM219 24234451 25348397 27629921 29427412 association,physical association anti bait coimmunoprecipitation,two hybrid,bimolecular fluorescence complementation ComPPI,IntAct
ECPAS IL13RA2 25348397 N/A physical interaction ComPPI
TRAPPC5 IL13RA2 25348397 N/A physical interaction ComPPI
CHI3L1 IL13RA2 24234451 25348397 27629921 28143526 physical association fluorescence polarization spectroscopy,pull down ComPPI,IntAct
IL13 IL13RA2 11003391 12704343 20223216 26471366 27898060 8663118 stimulant N/A OmniPath
IL4R IL13RA2 12704343 27898060 N/A N/A OmniPath
IL13RA1 IL13RA2 12704343 27898060 N/A N/A OmniPath
IL13RA2 IL13RA1 12704343 27898060 N/A N/A OmniPath

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