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GENE：MLF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MLF1
FullNmae myeloid leukemia factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7125
EnsembleID ENSG00000178053
Uniprot P58340

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MLF1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MLF1 GO:0002318,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005929,GO:0006351,GO:0006355,GO:0007049,GO:0019904,GO:0036064,GO:0048471,GO:1901796,GO:1902806

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MLF1 hsa:4291 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MLF1 CEBPD 21072181 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 MLF1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 MLF1 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MLF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000451A1 MLF1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
KLHL38 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PDE4DIP MLF1 25348397 N/A physical interaction ComPPI
MOS MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NDC80 MLF1 25348397 N/A physical interaction ComPPI
BAG3 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ZBED4 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MCM5 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NUDCD3 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ERCC3 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PRKACB MLF1 25348397 N/A physical interaction ComPPI
ERBB2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SETDB1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CDC16 MLF1 25348397 N/A physical interaction ComPPI
NR1H3 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
IRS4 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HERC1 MLF1 25348397 N/A physical interaction ComPPI
BAG1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HAX1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BUB1 MLF1 25348397 N/A physical interaction ComPPI
TARBP2 MLF1 25348397 N/A physical interaction ComPPI
PLEC MLF1 25348397 N/A physical interaction ComPPI
DNAJB2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
AKAP11 MLF1 25348397 N/A physical interaction ComPPI
PRKAR1B MLF1 25348397 N/A physical interaction ComPPI
PROZ MLF1 25348397 N/A physical interaction ComPPI
DUSP16 MLF1 25348397 N/A physical interaction ComPPI
TP73 MLF1 25348397 N/A physical interaction ComPPI
RAD51 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BRCA2 MLF1 25348397 N/A physical interaction ComPPI
EPB41L2 MLF1 25348397 N/A physical interaction ComPPI
YWHAE MLF1 22151054 24234451 25348397 27898060 N/A isothermal titration calorimetry,x-ray crystallography ComPPI,IntAct,OmniPath
RAF1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SKP2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GNB5 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HDAC6 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TBCE MLF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
STK11 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
COPS3 MLF1 14525934 15861129 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
RIPK1 MLF1 25348397 N/A physical interaction ComPPI
PSMD2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TRO MLF1 25348397 N/A physical interaction ComPPI
TSHR MLF1 25348397 N/A physical interaction ComPPI
ETF1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
WNK1 MLF1 25348397 N/A physical interaction ComPPI
GRIK5 MLF1 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GNA15 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PMF1 MLF1 25348397 N/A physical interaction ComPPI
KIF20B MLF1 25348397 N/A physical interaction ComPPI
RGPD5 MLF1 25348397 N/A physical interaction ComPPI
CENPU MLF1 14525934 15116101 25348397 27898060 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
STUB1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SMARCD2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HUS1B MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
DNAJB6 MLF1 23414517 24234451 25036637 25348397 physical association physical interaction,two hybrid fragment pooling approach,luminescence based mammalian interactome mapping ComPPI,IntAct
RCN1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SYNRG MLF1 25348397 N/A physical interaction ComPPI
BAG2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ZWINT MLF1 25348397 N/A physical interaction ComPPI
TUBB1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
DSN1 MLF1 25348397 N/A physical interaction ComPPI
NLRP12 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ALMS1 MLF1 25348397 N/A physical interaction ComPPI
KNL1 MLF1 25348397 N/A physical interaction ComPPI
ZC3H7B MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NMT1 MLF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF11 MLF1 25348397 N/A physical interaction ComPPI
MCM7 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GNAZ MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SIM2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
EIF2AK4 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GNB1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GET4 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MAP1B MLF1 25348397 N/A physical interaction ComPPI
RCN2 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CCDC88A MLF1 25348397 N/A physical interaction ComPPI
MAGEA11 MLF1 14525934 16189514 24234451 25348397 26871637 physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
USP18 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SIRT6 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TRIM17 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TLR7 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
FKBPL MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
IRF2BP1 MLF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HYPK MLF1 25348397 N/A physical interaction ComPPI
APOB MLF1 25348397 N/A physical interaction ComPPI
MLF1 DNAJB8 25348397 N/A physical interaction ComPPI
MLF1 ERCC6L 25348397 N/A physical interaction ComPPI
MLF1 FAM83H 25348397 N/A physical interaction ComPPI
MLF1 SPC24 25348397 N/A physical interaction ComPPI
MLF1 WASHC2A 25348397 N/A physical interaction ComPPI
MLF1 HEATR5B 25348397 N/A physical interaction ComPPI
MLF1 CDK5RAP2 25348397 N/A physical interaction ComPPI
MLF1 ATG2B 25348397 N/A physical interaction ComPPI
MLF1 HAUS6 25348397 N/A physical interaction ComPPI
MLF1 HAUS8 25348397 N/A physical interaction ComPPI
MLF1 CRYBG3 25348397 N/A physical interaction ComPPI
MLF1 CEP295 25348397 N/A physical interaction ComPPI
MLF1 AARSD1 25348397 N/A physical interaction ComPPI
MLF1 THSD4 25348397 N/A physical interaction ComPPI
MLF1 RABGAP1L 25348397 N/A physical interaction ComPPI
MLF1 RABGAP1L 25348397 N/A physical interaction ComPPI
MLF1 PRKACG 25348397 N/A physical interaction ComPPI
MLF1 DNAJC13 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MLF1 EDRF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MLF1 FYB2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MLF1 TET3 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 PSMD3 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 REC8 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 CRAT 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 CLCN2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 EIPR1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 TFDP3 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 GTF2IRD2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TRIM43 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MLF1 YWHAZ 12176995 14525934 N/A experimental interaction detection,two hybrid HPRD
NRBP1 MLF1 12176995 14525934 N/A experimental interaction detection,two hybrid HPRD
MLF1 MLF1 24234451 25036637 physical association luminescence based mammalian interactome mapping IntAct
TRAF2 MLF1 24234451 30561431 association virotrap IntAct
TANK MLF1 24234451 30561431 association virotrap IntAct
TNIP2 MLF1 24234451 30561431 association virotrap IntAct
TNIP1 MLF1 24234451 30561431 association virotrap IntAct
MLF1 COPS3 15861129 27898060 stimulant N/A OmniPath

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