GENE：MREG
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MREG |
| FullNmae | melanoregulin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25478 |
| EnsembleID | ENSG00000118242 |
| Uniprot | Q8N565 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MREG | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MREG | GO:0005515,GO:0005765,GO:0016324,GO:0030318,GO:0030659,GO:0031090,GO:0031902,GO:0032400,GO:0032402,GO:0032991,GO:0033162,GO:0035091,GO:0042470,GO:0072385,GO:0090382 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | MREG | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| ETS1 | MREG | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | MREG | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | MREG | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | MREG | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | MREG | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | MREG | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000ED600 | MREG | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002C0FCB | MREG | 20371350 25416803 27292025 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS000003ABC4 | MREG | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000039E1E1 | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEF5F | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E92A8 | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000221168 | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CE28 | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CC20C | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000015F70F | MREG | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PTPN1 | MREG | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FGFR1 | MREG | 25348397 | N/A | physical interaction | ComPPI |
| SPAG9 | MREG | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | MREG | 25348397 | N/A | physical interaction | ComPPI |
| UBA5 | MREG | 25348397 | N/A | physical interaction | ComPPI |
| TOR1AIP1 | MREG | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |