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GENE：NFIL3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NFIL3
FullNmae nuclear factor, interleukin 3 regulated
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7787
EnsembleID ENSG00000165030
Uniprot Q16649

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NFIL3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NFIL3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NFIL3 GO:0000122,GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0001227,GO:0001779,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0006355,GO:0006357,GO:0006366,GO:0006955,GO:0007623,GO:0010628,GO:0042802,GO:0045892,GO:0045892,GO:0045893,GO:0071353,GO:0090575

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NFIL3 hsa:4783 path:hsa04710 Circadian rhythm - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 NFIL3 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NFIL3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 NFIL3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA2 NFIL3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC NFIL3 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 NFIL3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NFIL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 NFIL3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 NFIL3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000345DEB NFIL3 24423866 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
NFIL3 CREB3 25361965 interaction type N/A PTMCode2
CREB3 NFIL3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GMCL1 NFIL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CBX8 NFIL3 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
BHLHE40 NFIL3 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
DR1 NFIL3 14525934 25348397 27898060 8836190 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
NFIL3 CREB3 20102225 24234451 25348397 N/A peptide array,in vitro ComPPI,IntAct
NFIL3 MAFG 25348397 N/A physical interaction ComPPI
NFIL3 MAFF 25348397 N/A physical interaction ComPPI
NFIL3 BATF 25348397 N/A physical interaction ComPPI
NFIL3 DDIT3 20102225 24234451 25348397 N/A peptide array,physical interaction ComPPI,IntAct
NFIL3 TRAF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NFIL3 AMOTL2 21516116 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NFIL3 DELEC1 25348397 N/A physical interaction ComPPI
NFIL3 CREB1 20102225 24234451 25348397 25609649 association peptide array,physical interaction,tandem affinity purification ComPPI,IntAct
NFIL3 DNMT3L 25348397 N/A physical interaction ComPPI
NFIL3 COP1 25348397 N/A physical interaction ComPPI
NFIL3 STK40 25348397 N/A physical interaction ComPPI
NFIL3 ATF1 20102225 24234451 25348397 N/A peptide array,physical interaction ComPPI,IntAct
NFIL3 MCM9 25348397 N/A physical interaction ComPPI
NFIL3 MYC 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
NFIL3 FHL1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
NFIL3 CREB3L3 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
NFIL3 PIH1D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NFIL3 RINT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NFIL3 SUMO1P1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NFIL3 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NFIL3 NFIL3 12805554 14525934 20102225 24234451 N/A experimental interaction detection,peptide array HPRD,IntAct
STAT6 NFIL3 17312100 27898060 stimulant N/A OmniPath

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