Gene Information gene info

  1. Home

GENE：RXRB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RXRB
FullNmae retinoid X receptor beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10478
EnsembleID ENSG00000204231
Uniprot P28702

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RXRB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RXRB GO:0000785,GO:0000977,GO:0000981,GO:0001228,GO:0003707,GO:0004879,GO:0004879,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005829,GO:0008270,GO:0009755,GO:0030154,GO:0030501,GO:0032526,GO:0042789,GO:0043401,GO:0044323,GO:0045893,GO:0045944,GO:0045944,GO:0045944,GO:0048384,GO:0048856,GO:0070564,GO:0090575,GO:0090575,GO:0090575,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RXRB hsa:6257 path:hsa03320 PPAR signaling pathway - Homo sapiens (human)
RXRB hsa:6257 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
RXRB hsa:6257 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
RXRB hsa:6257 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
RXRB hsa:6257 path:hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)
RXRB hsa:6257 path:hsa05200 Pathways in cancer - Homo sapiens (human)
RXRB hsa:6257 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
RXRB hsa:6257 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
RXRB hsa:6257 path:hsa05216 Thyroid cancer - Homo sapiens (human)
RXRB hsa:6257 path:hsa05222 Small cell lung cancer - Homo sapiens (human)
RXRB hsa:6257 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
RXRB hsa:6257 path:hsa05226 Gastric cancer - Homo sapiens (human)
RXRB hsa:6257 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NR3C1 RXRB 20211142 23180781 physical association pull down InnateDB
PPARG RXRB 15130092 20211142 23180781 23331499 stimulation,physical association pull down InnateDB,SignaLink,SignaLink
RARA RXRB 10828175 23331499 stimulation N/A SignaLink,SignaLink
RARG RXRB 10721822 15604093 18988627 23331499 stimulation N/A SignaLink,SignaLink
RXRB RARA 10721822 15604093 16189514 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
RXRB RARG 10721822 15604093 21071413 23331499 stimulation N/A SignaLink,SignaLink
RXRB PPARG 10882139 15604093 18988627 23331499 stimulation N/A SignaLink,SignaLink
THRA RXRB 10845098 1331778 23331499 stimulation N/A SignaLink
NR0B2 RXRB 10594021 10845098 23331499 stimulation N/A SignaLink
VDR RXRB 11094341 23331499 stimulation N/A SignaLink
RXRB VDR 10721933 15604093 23331499 stimulation N/A SignaLink
RXRB THRA 10721822 23331499 stimulation N/A SignaLink
RXRB THRB 10976919 15604093 23331499 stimulation N/A SignaLink
NR2F1 RXRB 10900149 23331499 stimulation N/A SignaLink
NR2F2 RXRB 10900149 23331499 stimulation N/A SignaLink
THRB RXRB 12585964 15604093 23331499 stimulation N/A SignaLink
PPARD RXRB 12576510 15604093 23331499 stimulation N/A SignaLink
RARB RXRB 12112017 1331778 15604093 23331499 stimulation N/A SignaLink
RXRB RARB 12112017 15604093 23331499 stimulation N/A SignaLink
RXRB PPARD 11237216 15604093 23331499 stimulation N/A SignaLink
NR1H2 RXRB 10187832 14993927 15604093 23331499 stimulation N/A SignaLink
RXRB NR1H2 14993927 15604093 23331499 stimulation N/A SignaLink
RXRB PPARA 23331499 8384714 stimulation N/A SignaLink
PPARA RXRB 23331499 8384714 stimulation N/A SignaLink
RXRB NR4A2 15604093 23331499 9636132 stimulation N/A SignaLink
NR4A2 RXRB 15604093 23331499 7705655 7758108 9636132 stimulation N/A SignaLink
RXRB NR2F1 10900149 23331499 stimulation N/A SignaLink
RXRB NR2F2 10900149 23331499 stimulation N/A SignaLink
NRIP1 RXRB 12549917 23331499 9626662 stimulation N/A SignaLink
RXRB NRIP1 11278635 12403842 12549917 23331499 9013766 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 RXRB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RXRB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RXRB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RXRB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RXRB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RXRB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RXRB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RXRB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC RXRB N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F4AC3 RXRB 16822819 23824327 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS0000134ADC RXRB 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS0000237AF9 RXRB 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 RXRB 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE RXRB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 RXRB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000058BB84 RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E177F RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDE70 RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000033B548 RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003B6B84 RXRB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A RXRB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B RXRB 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NCOA1 RXRB 25361965 interaction type N/A PTMCode2
RXRB NCOA1 25361965 interaction type N/A PTMCode2
NRIP1 RXRB 25361965 interaction type N/A PTMCode2
RXRB NRIP1 25361965 interaction type N/A PTMCode2
NCOA3 RXRB 25361965 interaction type N/A PTMCode2
RXRB NCOA3 25361965 interaction type N/A PTMCode2
NR1H3 RXRB 25361965 interaction type N/A PTMCode2
RXRB NR1H3 25361965 interaction type N/A PTMCode2
RXRB RXRB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TXLNA RXRB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CDC5L RXRB 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SPOPL RXRB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RARA RXRB 14525934 15604093 16189514 21988832 24234451 25303530 25348397 26871637 association,physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
RARB RXRB 1331778 14525934 15604093 25348397 N/A experimental interaction detection,physical interaction,two hybrid prey pooling approach,two hybrid ComPPI,HPRD
NRIP1 RXRB 11278635 12403842 12549917 14525934 25348397 9013766 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
VCP RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
APPL1 RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PICK1 RXRB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VDR RXRB 14525934 15604093 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NCOA3 RXRB 14525934 25348397 9267036 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NCOA1 RXRB 14525934 25348397 7481822 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
AKAP13 RXRB 14525934 25348397 9627117 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PCSK6 RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
THRA RXRB 1331778 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
THRB RXRB 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PPARA RXRB 25348397 N/A physical interaction ComPPI
NR1H3 RXRB 14525934 15604093 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
GTF2H1 RXRB 25348397 N/A physical interaction ComPPI
SOS2 RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
NR1I2 RXRB 14525934 15604093 25348397 9727070 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
HSP90B1 RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MACO1 RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PPARG RXRB 14525934 15604093 24234451 25348397 25609649 association two hybrid,physical interaction,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
PPARD RXRB 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NR1H2 RXRB 10187832 14525934 15604093 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
NR4A2 RXRB 14525934 15604093 25348397 7705655 7758108 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NR0B2 RXRB 10594021 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GRK2 RXRB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAF11 RXRB 14525934 25348397 8670810 N/A experimental interaction detection,in vivo ComPPI,HPRD
RXRB NR2E3 10611353 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RXRB TACC2 15207008 25348397 27898060 N/A in vitro ComPPI,OmniPath
RXRB SPOP 14525934 16189514 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RXRB NR2C2 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RXRB MAP4 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RXRB NR3C1 25348397 N/A physical interaction ComPPI
RXRB RARG 14525934 15604093 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
RXRB ZDHHC12 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RXRB CACNA1B 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
RXRB PTMS 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
RXRB FLYWCH2 25348397 N/A physical interaction ComPPI
RXRB CCNK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RXRB CDC42BPB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RXRB C2CD5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RXRB POLR3F 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RXRB AFF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RXRB MCAT 25348397 N/A physical interaction ComPPI
RXRB WRAP53 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RXRB MRPS10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RXRB NR1H4 25348397 N/A physical interaction ComPPI
RXRB APCDD1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB KIF5A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB DNAJB14 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB MCFD2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB CLTA 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB TBCA 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB CPLX1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB ATP5ME 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB RAB3GAP1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB KLHL11 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB RGPD5 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB SSB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB EIF3A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB STX18 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB MBP 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB PPP3CA 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RXRB MT-CO2 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
MYG1 RXRB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RXRB RXRB 11782480 14525934 N/A experimental interaction detection HPRD
RXRB PPARA 11237216 27898060 8384714 stimulant N/A OmniPath
PPARA RXRB 27898060 8384714 stimulant N/A OmniPath
RARA RXRB 10721822 10828175 15604093 16189514 21988832 27898060 stimulant N/A OmniPath
RXRB RARA 10721822 10828175 1310351 15604093 16189514 21988832 27898060 stimulant N/A OmniPath
RXRB NRIP1 11278635 12403842 12549917 27898060 9013766 stimulant N/A OmniPath
VDR RXRB 1072193 11094341 15604093 21988832 27898060 stimulant N/A OmniPath
RXRB VDR 1072193 11094341 15604093 21988832 27898060 stimulant N/A OmniPath
RXRB PPARG 10882139 11237216 15130092 1560409 15604093 20211142 22205725 25609649 27898060 stimulant N/A OmniPath
PPARG RXRB 10882139 15130092 1560409 15604093 20211142 22205725 25609649 27898060 stimulant N/A OmniPath
RXRB PPARD 11237216 12576510 1560409 15604093 22205725 27898060 stimulant N/A OmniPath
PPARD RXRB 11237216 12576510 1560409 15604093 22205725 27898060 stimulant N/A OmniPath
NR2F2 RXRB 10900149 27898060 stimulant N/A OmniPath
RXRB NR2F2 10900149 27898060 stimulant N/A OmniPath
NR0B2 RXRB 10594021 108451 27898060 stimulant N/A OmniPath
RXRB NR1H2 10187832 14993927 1499393 15604093 27898060 stimulant N/A OmniPath
NR1H2 RXRB 10187832 14993927 1499393 15604093 27898060 stimulant N/A OmniPath
RARG RXRB 1072182 10721822 1310351 1560409 15604093 27898060 stimulant N/A OmniPath
RXRB RARG 1072182 10721822 1310351 1560409 15604093 27898060 stimulant N/A OmniPath
THRA RXRB 10721822 10845098 1331778 27898060 stimulant N/A OmniPath
RXRB THRA 10721822 10845098 10976919 1331778 27898060 stimulant N/A OmniPath
THRB RXRB 10976919 12585964 1560409 15604093 27898060 stimulant N/A OmniPath
RXRB THRB 10976919 12585964 1560409 15604093 27898060 stimulant N/A OmniPath
RARB RXRB 12112017 1310351 1331778 1560409 15604093 25416956 27898060 stimulant N/A OmniPath
RXRB RARB 12112017 1310351 1331778 1560409 15604093 25416956 27898060 stimulant N/A OmniPath
RXRB NR2F1 10900149 27898060 stimulant N/A OmniPath
RXRB NR4A2 15604093 27898060 7705655 7758108 9636132 stimulant N/A OmniPath

Visualization










  Return