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GENE：CFLAR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CFLAR
FullNmae CASP8 and FADD like apoptosis regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1876
EnsembleID ENSG00000003402
Uniprot O15519

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CFLAR necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CFLAR necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
CFLAR mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CFLAR immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CFLAR ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CFLAR autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CFLAR apoptosis 36400248 CASP8 and FADD Like Apoptosis Regulator (CFLAR) is a key anti-apoptotic regulator for resistance to apoptosis mediated by Fas and TRAIL. retulator signature
CFLAR apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CFLAR GO:0002020,GO:0005123,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0006508,GO:0006915,GO:0006915,GO:0007519,GO:0008047,GO:0010667,GO:0010976,GO:0014732,GO:0014842,GO:0014866,GO:0030182,GO:0030216,GO:0030218,GO:0031264,GO:0031265,GO:0032869,GO:0033574,GO:0042060,GO:0043065,GO:0043066,GO:0043123,GO:0043403,GO:0044877,GO:0051092,GO:0060544,GO:0070374,GO:0071364,GO:0071392,GO:0071456,GO:0071549,GO:0071732,GO:0072126,GO:0097153,GO:0097342,GO:1901740,GO:1902042,GO:1902042,GO:1903055,GO:1903427,GO:1903845,GO:1903944,GO:2000347,GO:2001237,GO:2001237

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CFLAR hsa:8837 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
CFLAR hsa:8837 path:hsa04140 Autophagy - animal - Homo sapiens (human)
CFLAR hsa:8837 path:hsa04210 Apoptosis - Homo sapiens (human)
CFLAR hsa:8837 path:hsa04217 Necroptosis - Homo sapiens (human)
CFLAR hsa:8837 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
CFLAR hsa:8837 path:hsa05142 Chagas disease - Homo sapiens (human)
CFLAR hsa:8837 path:hsa05160 Hepatitis C - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CFLAR MLKL 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16498403 16940415 17462996 18641653 19090789 19498109 19524512 19524513 19597341 19632174 19838173 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 24366341 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9242610 9488730 9759866 interaction type N/A ACSN
RIPK3 CFLAR 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16498403 16940415 17462996 18641653 19090789 19498109 19524512 19524513 19597341 19632174 19838173 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 24366341 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9242610 9488730 9759866 interaction type N/A ACSN
CFLAR DAXX 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26192618 26587781 26653790 26972597 27984721 28574505 9488730 9759866 interaction type N/A ACSN
CFLAR FAF1 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
CFLAR FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
CFLAR FAS 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
FADD CFLAR 11003656 11274345 1134007 11583996 12215447 12220669 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17047155 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23180781 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
RIPK1 CFLAR 11002417 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17047155 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23180781 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
TRAF2 CFLAR 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26192618 26587781 26653790 26972597 27984721 28574505 9488730 9759866 interaction type N/A ACSN
CFLAR ATG3 12215447 15760909 17462996 19838173 23301705 23377657 23725295 24070470 26192618 26972597 association N/A ACSN
NFKB1 CFLAR 11359904 13679070 15367674 21725609 23178297 23180781 23572150 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
MYC CFLAR 11274345 11283613 11283614 11359904 11704864 15367674 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 26192618 28536364 interaction type N/A ACSN
ITCH CFLAR 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157 26192618 26972597 interaction type N/A ACSN
CFLAR FADD 23180781 9208847 physical association anti tag coimmunoprecipitation InnateDB
CASP8 CFLAR 22421964 23180781 9208847 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 CFLAR 23180781 9575181 physical association anti tag coimmunoprecipitation InnateDB
CFLAR TRAF2 15024054 23180781 physical association anti tag coimmunoprecipitation InnateDB
CFLAR CASP8 12097160 15024054 17047155 23180781 9380701 cleavage reaction,physical association anti tag coimmunoprecipitation,protease assay InnateDB
MAP3K14 CFLAR 11002417 23180781 physical association anti tag coimmunoprecipitation InnateDB
CFLAR DEDD 17193921 23180781 physical association anti tag coimmunoprecipitation InnateDB
FAS CFLAR 15993755 23180781 physical association anti tag coimmunoprecipitation InnateDB
EP300 CFLAR 15286281 23180781 physical association anti tag coimmunoprecipitation InnateDB
BCL6 CFLAR 19965633 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATG3 CFLAR 19838173 23180781 physical association anti tag coimmunoprecipitation InnateDB
CFLAR CFLAR 14585074 26467481 9794838 bind,down-regulates activity N/A Signor

Source Target Pmid Interactiontype Methods Database
DOK2 CFLAR 20005715 interaction type N/A PSP
FADD CFLAR 20005715 interaction type N/A PSP
NOD1 CFLAR 20005715 interaction type N/A PSP
TRAF1 CFLAR 20005715 interaction type N/A PSP
TRAF2 CFLAR 20005715 interaction type N/A PSP
TRAF3 CFLAR 20005715 interaction type N/A PSP
DOK2 CFLAR 17353931 20005715 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR CFLAR 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CFLAR 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CFLAR 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CFLAR 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CFLAR 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CFLAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATM CFLAR 19351839 20876284 trascriptional regulation,stimulation inferred by curator TFlink
DEDD CFLAR 17193921 trascriptional regulation,stimulation inferred by curator TFlink
HDAC9 CFLAR 15540114 20087862 trascriptional regulation,stimulation inferred by curator TFlink
IRF8 CFLAR 19155307 trascriptional regulation,stimulation inferred by curator TFlink
MYC CFLAR 20348907 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 CFLAR 15723831 15750764 15986355 18222423 19343319 trascriptional regulation,stimulation inferred by curator TFlink
PPARG CFLAR 17172826 trascriptional regulation,stimulation inferred by curator TFlink
RELA CFLAR 15723831 15986355 18222423 19343319 trascriptional regulation,stimulation inferred by curator TFlink
RUNX3 CFLAR 17956589 trascriptional regulation,stimulation inferred by curator TFlink
SIRT1 CFLAR 22483777 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 CFLAR 18222423 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CFLAR N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000134ADC CFLAR 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS00002F3336 CFLAR 23807165 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 CFLAR 25416803 28097098 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PRKCA CFLAR 22135298 phosphorylation N/A PhosphoSite
PRKCB CFLAR 22135298 phosphorylation N/A PhosphoSite
AKT1 CFLAR 22135298 phosphorylation N/A PhosphoSite
RIPK2 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR RIPK2 25361965 interaction type N/A PTMCode2
BCL2L1 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR BCL2L1 25361965 interaction type N/A PTMCode2
RAF1 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR RAF1 25361965 interaction type N/A PTMCode2
CASP10 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR CASP10 25361965 interaction type N/A PTMCode2
CFLAR CASP8 25361965 interaction type N/A PTMCode2
CASP8 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR DEDD 25361965 interaction type N/A PTMCode2
DEDD CFLAR 25361965 interaction type N/A PTMCode2
CFLAR MAP2K7 25361965 interaction type N/A PTMCode2
MAP2K7 CFLAR 25361965 interaction type N/A PTMCode2
TP53 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR TP53 25361965 interaction type N/A PTMCode2
CASP3 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR CASP3 25361965 interaction type N/A PTMCode2
MAP2K1 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR MAP2K1 25361965 interaction type N/A PTMCode2
FADD CFLAR 25361965 interaction type N/A PTMCode2
CFLAR FADD 25361965 interaction type N/A PTMCode2
RIPK1 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR RIPK1 25361965 interaction type N/A PTMCode2
NFKB1 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR NFKB1 25361965 interaction type N/A PTMCode2
TNFRSF10A CFLAR 25361965 interaction type N/A PTMCode2
CFLAR TNFRSF10A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DAXX CFLAR 25348397 N/A coimmunoprecipitation,physical interaction,physical interaction,in vivo ComPPI
NUDCD3 CFLAR 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BCL2L1 CFLAR 10197438 14525934 25348397 27898060 9326610 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
MAP3K14 CFLAR 25348397 N/A physical interaction ComPPI
CASP2 CFLAR 14525934 25348397 9228018 N/A experimental interaction detection,in vitro ComPPI,HPRD
CFLAR CASP3 14525934 25348397 9208847 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CFLAR PSEN2 10069390 14525934 25348397 9219695 9990034 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CFLAR TRAF1 14525934 24234451 25348397 25416956 9208847 physical association experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
CFLAR CASP10 12887920 14525934 23541952 24234451 25241761 25348397 9208847 9228018 9289491 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
CFLAR CASP8 12097160 12215447 12887920 14525934 17047155 17159907 24234451 24438025 25348397 9208847 9289491 9380701 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,protease assay,in vitro,in vivo,protein cleavage ComPPI,HPRD,IntAct
CFLAR TRAF2 14525934 25348397 9208847 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CFLAR IKBKB 11002417 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CFLAR RIPK1 10837247 14525934 17047155 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CFLAR RIPK2 14525934 25348397 9575181 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CFLAR TNFRSF10B 11193041 11940602 14525934 19343040 23142077 25348397 27898060 9325248 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
CFLAR DEDD 11741985 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CFLAR DEDD2 11741985 11965497 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CFLAR NFKB1 13679070 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
CFLAR CASP6 14525934 25348397 9228018 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CFLAR CASP7 14525934 25348397 9228018 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CFLAR FADD 14525934 17047155 24234451 25348397 9208847 association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
CFLAR MAP2K4 14525934 17110930 25348397 N/A anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD
CFLAR MAP2K7 25348397 N/A anti tag coimmunoprecipitation,in vivo ComPPI
CFLAR RAF1 10837247 14525934 21988832 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo ComPPI,HPRD,IntAct
CFLAR SF3B3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CFLAR DOK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CFLAR FAS 21803845 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CFLAR TNFRSF10A 19427028 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CFLAR NOD1 25348397 N/A physical interaction ComPPI
CFLAR TRAF3 25348397 N/A physical interaction ComPPI
CFLAR TP53 25348397 N/A physical interaction ComPPI
CFLAR ITCH 25348397 N/A physical interaction ComPPI
CFLAR XRCC6 25348397 N/A physical interaction ComPPI
CFLAR TNFSF10 20097879 23678861 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CFLAR ATG3 25348397 N/A physical interaction ComPPI
CFLAR CBLB 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
CFLAR FASLG 25348397 N/A physical interaction ComPPI
CFLAR STUB1 24234451 25036637 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
CFLAR HSP90AA1 25348397 N/A physical interaction ComPPI
CFLAR HSP90AA2P 25348397 N/A physical interaction ComPPI
CFLAR SPATS1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CFLAR SMAD3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CFLAR GSN 25348397 N/A physical interaction ComPPI
CFLAR TICAM1 25348397 N/A physical interaction ComPPI
CFLAR PLIN5 25348397 N/A physical interaction ComPPI
CFLAR USP8 25348397 N/A physical interaction ComPPI
CFLAR USP15 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR EPPK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR FSCN1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR RPS29 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR FBL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR SF3B1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR CDC37 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR SUN2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR RADIL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR HNRNPL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR EIF3F 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR TUFM 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR MAP2K1 25348397 N/A anti tag coimmunoprecipitation ComPPI
CFLAR PSMD2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CFLAR FKBPL 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CFLAR CACYBP 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CFLAR CD247 24234451 24502978 25348397 association pull down ComPPI,IntAct
MIF CFLAR 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PRKCB CFLAR 19343040 27898060 N/A N/A OmniPath
ITCH CFLAR 18559494 18786561 19090833 19808964 21474069 27898060 inhibition N/A OmniPath
CFLAR ATG3 19838173 27898060 inhibition N/A OmniPath
CFLAR TRAF2 10837247 15024054 27898060 9208847 N/A N/A OmniPath
TRAF2 CFLAR 10837247 15024054 27898060 9208847 N/A N/A OmniPath
RIPK2 CFLAR 27898060 9575181 N/A N/A OmniPath
CFLAR FADD 12220669 14637155 16469705 17047155 18708583 20829884 21737330 22322857 27898060 9208847 9217161 9228018 9326610 inhibition N/A OmniPath
FADD CFLAR 12220669 14637155 16469705 17047155 18708583 20829884 21737330 22322857 27898060 9208847 9228018 9326610 N/A N/A OmniPath
CFLAR MAP3K14 11002417 27898060 N/A N/A OmniPath
MAP3K14 CFLAR 11002417 27898060 N/A N/A OmniPath
CFLAR NFKB1 13679070 27898060 inhibition N/A OmniPath
AKT1 CFLAR 19339247 27898060 inhibition N/A OmniPath
MAPK14 CFLAR 19597496 27898060 stimulant N/A OmniPath
CFLAR CASP8 11741985 12097160 12215447 12887920 14585074 15024054 15280356 17047155 17159907 19343040 19416807 19710364 21737329 21737330 22322857 22421964 22864571 24438025 26186194 27898060 9208847 9217161 9228018 9289491 9326610 9380701 9794838 9880531 inhibition N/A OmniPath
CASP8 CFLAR 11741985 12097160 12215447 12887920 15024054 15280356 17047155 17159907 19343040 19416807 19710364 21737329 21737330 22322857 22421964 22864571 24438025 26186194 27898060 9208847 9228018 9289491 9326610 9380701 9794838 N/A N/A OmniPath
CFLAR CASP10 12887920 21737330 23541952 25241761 27898060 9208847 9228018 9289491 inhibition N/A OmniPath
FAS CFLAR 15993755 27898060 9208847 9325248 N/A N/A OmniPath
AR CFLAR 15731171 27898060 stimulant N/A OmniPath
CBL CFLAR 19597496 27898060 inhibition N/A OmniPath
CFLAR RIPK1 10837247 11002417 17047155 21737330 27898060 inhibition N/A OmniPath
RIPK1 CFLAR 10837247 11002417 17047155 21737330 27898060 N/A N/A OmniPath

Visualization










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