Gene Information gene info

GENE:RAD51C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAD51C
FullNmae RAD51 paralog C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9820
EnsembleID ENSG00000108384
Uniprot O43502

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAD51C mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAD51C autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAD51C GO:0000400,GO:0000400,GO:0000707,GO:0000722,GO:0000724,GO:0003677,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005654,GO:0005657,GO:0005657,GO:0005737,GO:0005739,GO:0005829,GO:0006281,GO:0006310,GO:0007062,GO:0007066,GO:0007131,GO:0007141,GO:0007283,GO:0008821,GO:0008821,GO:0010971,GO:0030054,GO:0033063,GO:0033063,GO:0033065,GO:0033065,GO:0043231,GO:0048471,GO:0140664

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RAD51C hsa:5889 path:hsa03440 Homologous recombination - Homo sapiens (human)
RAD51C hsa:5889 path:hsa03460 Fanconi anemia pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 RAD51C 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RAD51C 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 RAD51C 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RAD51C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAD51C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAD51C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAD51C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAD51C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RAD51C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RAD51C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 RAD51C 18362358 rna interference,inhibition array technology miRSponge
URS0000171CD1 RAD51C 18362358 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 RAD51C 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001A405B RAD51C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 RAD51C 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RAD51C XRCC3 25361965 interaction type N/A PTMCode2
XRCC3 RAD51C 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
XRCC2 RAD51C 11842113 24141787 24234451 25348397 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PTPN9 RAD51C 25348397 N/A physical interaction ComPPI
RAD51 RAD51C 12427746 14525934 15065660 16395335 24141787 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo,immunodepleted coimmunoprecipitation ComPPI,HPRD,IntAct,OmniPath
BRCA2 RAD51C 24141787 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction,immunodepleted coimmunoprecipitation ComPPI,IntAct
THBS3 RAD51C 25348397 N/A physical interaction ComPPI
DDX3X RAD51C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ADAMTS4 RAD51C 25348397 N/A physical interaction ComPPI
RAD51D RAD51C 10749867 11751635 11842113 14525934 14704354 24141787 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
TRIM25 RAD51C 25348397 N/A physical interaction ComPPI
IL12RB1 RAD51C 25348397 N/A physical interaction ComPPI
EFNB3 RAD51C 25348397 N/A physical interaction ComPPI
TGOLN2 RAD51C 25348397 N/A physical interaction ComPPI
RAD51B RAD51C 11744692 11751635 11751636 11842113 14525934 14704354 24141787 24234451 25348397 9469824 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,pull down,physical interaction,in vivo,electrophoretic mobility-based method,two hybrid ComPPI,HPRD,IntAct
RAD51C XRCC3 11331762 11459987 11744692 11751635 11842113 14525934 14704354 24005329 24141787 24234451 25348397 26496610 9469824 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro,in vivo,electrophoretic mobility-based method,two hybrid ComPPI,HPRD,IntAct
RAD51C APP 25348397 N/A physical interaction ComPPI
RAD51C SWSAP1 21965664 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
RAD51C BSG 25348397 N/A physical interaction ComPPI
RAD51C SPACA1 25348397 N/A physical interaction ComPPI
RAD51C CBWD1 25348397 N/A physical interaction ComPPI
RAD51C WNT4 25348397 N/A physical interaction ComPPI
RAD51C THBS4 25348397 N/A physical interaction ComPPI
RAD51C KLHL10 25348397 N/A physical interaction ComPPI
RAD51C CCDC140 25348397 N/A physical interaction ComPPI
RAD51C DKKL1 25348397 N/A physical interaction ComPPI
RAD51C FAM174A 25348397 N/A physical interaction ComPPI
RAD51C HELQ 24005329 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD51C PALB2 24141787 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction,immunodepleted coimmunoprecipitation ComPPI,IntAct
RAD51C CACNA2D3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RAD51C HRNR 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HENMT1 RAD51C 25348397 N/A physical interaction ComPPI
RAD18 RAD51C 19396164 27898060 stimulant N/A OmniPath

Visualization