GENE：STK10
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | STK10 |
| FullNmae | serine/threonine kinase 10 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11388 |
| EnsembleID | ENSG00000072786 |
| Uniprot | O94804 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| STK10 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| STK10 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| STK10 | GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005737,GO:0005829,GO:0005886,GO:0005886,GO:0006468,GO:0006468,GO:0007049,GO:0035579,GO:0042802,GO:0042803,GO:0046777,GO:0070062,GO:0071593,GO:0106310,GO:2000401,GO:2000401 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| STK10 | hsa:6793 | path:hsa04914 | Progesterone-mediated oocyte maturation - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | STK10 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | STK10 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | STK10 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | STK10 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | STK10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00005651EE | STK10 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003CC709 | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000160683 | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000031B6ED | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E2232 | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000008B558 | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000000E601 | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | STK10 | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CD81 | STK10 | 25348397 | N/A | physical interaction | ComPPI |
| ENO1 | STK10 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | STK10 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | STK10 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | STK10 | 25348397 | N/A | physical interaction | ComPPI |
| SHMT2 | STK10 | 25348397 | N/A | physical interaction | ComPPI |
| STK10 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| STK10 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| STK10 | KIFC1 | 25348397 | N/A | physical interaction | ComPPI |
| STK10 | LAMP1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| STK10 | STK10 | 14525934 17192257 18239682 24234451 | N/A | cosedimentation in solution,cross-linking study,experimental interaction detection,x-ray crystallography | HPRD,IntAct |
| TANK | STK10 | 24234451 30561431 | association | virotrap | IntAct |
| NONO | STK10 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| STK10 | PLK1 | 10980711 11854496 12207013 15611664 15713655 18477460 18615013 20603326 21454580 22081024 22281053 23442801 24349352 24785407 24844881 25660017 26012549 26114094 26206521 27898060 | N/A | N/A | OmniPath |
| STK10 | BLM | 16864798 27898060 | N/A | N/A | OmniPath |
| STK10 | MSN | 19255442 27898060 | inhibition | N/A | OmniPath |
| STK10 | SUB1 | 27898060 7809103 | N/A | N/A | OmniPath |