Gene Information gene info

GENE:CTCF

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CTCF
FullNmae CCCTC-binding factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13723
EnsembleID ENSG00000102974
Uniprot P49711

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CTCF pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CTCF mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CTCF autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CTCF GO:0000122,GO:0000122,GO:0000775,GO:0000793,GO:0000976,GO:0000978,GO:0000978,GO:0001221,GO:0001227,GO:0001673,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0006306,GO:0006349,GO:0007059,GO:0008270,GO:0008285,GO:0010628,GO:0040029,GO:0040029,GO:0043035,GO:0043035,GO:0043565,GO:0044027,GO:0045892,GO:0045893,GO:0045893,GO:0045893,GO:0070602,GO:0071459,GO:0071514,GO:0140588

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRAK2 CTCF 15670593 23180781 physical association anti tag coimmunoprecipitation InnateDB
CTCF CFTR 17696881 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
CTCF IFNG 19818655 23180781 physical association anti tag coimmunoprecipitation InnateDB
RASSF1 CTCF 20877461 23180781 physical association electrophoretic mobility supershift assay InnateDB
APOB CTCF 20877461 23180781 physical association electrophoretic mobility supershift assay InnateDB
ZMYND10 CTCF 20877461 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYC CTCF 20877461 23180781 physical association anti tag coimmunoprecipitation InnateDB
CTCF NOTCH3 23180781 24984200 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR CTCF 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 CTCF 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
ETS1 CTCF 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CTCF 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CTCF 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CTCF 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CTCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CTCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CTCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CTCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CTCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CTCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CTCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BCL3 CTCF 21912613 trascriptional regulation,stimulation inferred by curator TFlink
FOXH1 CTCF 19956589 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 CTCF 21912613 trascriptional regulation,stimulation inferred by curator TFlink
WT1 CTCF 24534946 trascriptional regulation,stimulation inferred by curator TFlink
YY1 CTCF 9756895 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 CTCF 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 CTCF 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 CTCF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 CTCF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 CTCF 23630541 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003808EC CTCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 CTCF 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KPNA2 CTCF 25348397 N/A physical interaction ComPPI
KANSL1 CTCF 25348397 N/A physical interaction ComPPI
TFAP4 CTCF 25348397 N/A physical interaction ComPPI
KPNA4 CTCF 25348397 N/A physical interaction ComPPI
NPM1 CTCF 25348397 N/A physical interaction ComPPI
SET CTCF 25348397 N/A physical interaction ComPPI
ZBTB48 CTCF 25348397 N/A physical interaction ComPPI
LMNA CTCF 25348397 N/A physical interaction ComPPI
BMI1 CTCF 25348397 N/A physical interaction ComPPI
SMAD4 CTCF 12099698 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAD21 CTCF 18219272 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AIM2 CTCF 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX17 CTCF 24234451 24725430 25348397 physical association two hybrid ComPPI,IntAct
KDM5B CTCF 24234451 24937458 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
SMAD3 CTCF 12099698 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
THRB CTCF 10625678 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
YBX1 CTCF 10906122 14525934 15229244 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PARP1 CTCF 14759373 19450526 20038529 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SIN3A CTCF 25348397 N/A physical interaction ComPPI
KSR2 CTCF 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
HDLBP CTCF 24234451 24725430 25348397 physical association anti bait coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct
RALA CTCF 24234451 24725430 25348397 physical association two hybrid ComPPI,IntAct
HMGB1 CTCF 11748221 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TRAF2 CTCF 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPS6 CTCF 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SMC1A CTCF 18219272 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
YY1 CTCF 25348397 N/A physical interaction ComPPI
H1-4 CTCF 25348397 N/A physical interaction ComPPI
POLR2A CTCF 12054881 14525934 17210645 21880767 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
SMC3 CTCF 25348397 N/A physical interaction ComPPI
EED CTCF 25348397 N/A physical interaction ComPPI
H3C1 CTCF 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAND1 CTCF 25348397 N/A physical interaction ComPPI
ZBTB33 CTCF 25348397 N/A physical interaction ComPPI
ZMYM2 CTCF 25348397 N/A physical interaction ComPPI
TRIM25 CTCF 25348397 N/A physical interaction ComPPI
H2AX CTCF 25348397 N/A physical interaction ComPPI
AURKAIP1 CTCF 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDK19 CTCF 25348397 N/A physical interaction ComPPI
CTCF CHD8 16949368 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
CTCF CHD7 25348397 N/A physical interaction ComPPI
CTCF SUZ12 18662993 21536749 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CTCF RXRA 25348397 N/A physical interaction ComPPI
CTCF TOP2A 25348397 N/A physical interaction ComPPI
CTCF H2AC20 25348397 N/A physical interaction ComPPI
CTCF H2AZ1 25348397 N/A physical interaction ComPPI
CTCF TAF3 25348397 N/A physical interaction ComPPI
CTCF SIRT7 25348397 N/A physical interaction ComPPI
CTCF ZMYM4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CTCF TOP2B 25348397 N/A physical interaction ComPPI
CTCF NCL 25348397 N/A physical interaction ComPPI
CTCF H1-1 25348397 N/A physical interaction ComPPI
CTCF FBL 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CTCF PRR11 25348397 N/A physical interaction ComPPI
CTCF IFI16 25348397 N/A physical interaction ComPPI
CTCF CHMP4B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CTCF RHOU 25348397 N/A physical interaction ComPPI
CTCF ZCRB1 25348397 N/A physical interaction ComPPI
CTCF DGCR8 25348397 N/A physical interaction ComPPI
CTCF PUM3 25348397 N/A physical interaction ComPPI
CTCF ZNF2 25348397 N/A physical interaction ComPPI
CTCF NOP53 25348397 N/A physical interaction ComPPI
CTCF ZUP1 25348397 N/A physical interaction ComPPI
CTCF POU5F1 19536159 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CTCF HSPB9 15503857 24234451 25348397 physical association two hybrid ComPPI,IntAct
CTCF MT-ND4 24234451 24725430 25348397 physical association two hybrid ComPPI,IntAct
CTCF RPL31 24234451 24725430 25348397 physical association two hybrid ComPPI,IntAct
CTCF CHD1L 24234451 24725430 25348397 physical association two hybrid ComPPI,IntAct
CTCF PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
CTCF MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
CTCF PCGF1 24234451 25348397 27505670 association tandem affinity purification ComPPI,IntAct
MKI67 CTCF 24234451 26949251 association anti tag coimmunoprecipitation IntAct
RRP1B CTCF 24234451 30021884 physical association cross-linking study IntAct
CTCF DNAJC21 24234451 30021884 physical association cross-linking study IntAct
SUMO1 CTCF 19029252 27898060 stimulant N/A OmniPath

Visualization