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GENE：PKNOX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PKNOX1
FullNmae PBX/knotted 1 homeobox 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9022
EnsembleID ENSG00000160199
Uniprot P55347

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PKNOX1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PKNOX1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PKNOX1 GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001525,GO:0003682,GO:0003700,GO:0005515,GO:0005634,GO:0005667,GO:0005737,GO:0006357,GO:0006366,GO:0030217,GO:0030218,GO:0043010,GO:0045944,GO:1990837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PKNOX1 PBX1 21900201 23180781 physical association anti tag coimmunoprecipitation InnateDB
PKNOX1 PLAU 23180781 9482740 physical association electrophoretic mobility supershift assay InnateDB
PKNOX1 POU2F1 15138251 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR PKNOX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PKNOX1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PKNOX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PKNOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PKNOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PKNOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PKNOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PKNOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PKNOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PKNOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D PKNOX1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000039A052 PKNOX1 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS000037D7E5 PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003883FE PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A405B PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000012930C PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002B3783 PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002075FA PKNOX1 23446348 25416803 27123834 27292025 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS000039E1E1 PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000042E1F PKNOX1 23446348 25416803 27123834 27292025 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000298BA3 PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000600E6 PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PKNOX1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000330617 PKNOX1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F PKNOX1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 PKNOX1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC PKNOX1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C PKNOX1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 PKNOX1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 PKNOX1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 PKNOX1 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 PKNOX1 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 PKNOX1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000007F792 PKNOX1 19536157 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000148B91 PKNOX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C PKNOX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 PKNOX1 25416803 27123834 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000C85B2 PKNOX1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 PKNOX1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F PKNOX1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB0E PKNOX1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 PKNOX1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A7F58 PKNOX1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HOXB6 PKNOX1 25361965 interaction type N/A PTMCode2
PKNOX1 HOXB6 25361965 interaction type N/A PTMCode2
PKNOX1 HOXA1 25361965 interaction type N/A PTMCode2
HOXA1 PKNOX1 25361965 interaction type N/A PTMCode2
PKNOX1 PAX6 25361965 interaction type N/A PTMCode2
PAX6 PKNOX1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VPS37C PKNOX1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFAP4 PKNOX1 25348397 N/A physical interaction ComPPI
HOXA1 PKNOX1 25348397 N/A physical interaction ComPPI
PBX4 PKNOX1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 PKNOX1 14525934 19559479 24234451 25348397 9482739 physical association two hybrid,experimental interaction detection,physical interaction,imaging technique,in vivo ComPPI,HPRD,IntAct
BORCS6 PKNOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FHL2 PKNOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMGB2 PKNOX1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRAF1 PKNOX1 25348397 N/A physical interaction ComPPI
PAX6 PKNOX1 25348397 N/A physical interaction ComPPI
RFX3 PKNOX1 25348397 N/A physical interaction ComPPI
MPP3 PKNOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BLOC1S5 PKNOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PKNOX1 MEIS1 10373562 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PKNOX1 PBX1 14525934 21900201 25348397 26186194 27898060 9482740 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PKNOX1 TLX1 11342305 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PKNOX1 HOXB6 10906782 14525934 25348397 27898060 7729685 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
PKNOX1 HOXD9 14525934 25348397 27898060 9079695 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
PKNOX1 ZBTB3 25348397 N/A physical interaction ComPPI
PKNOX1 POU2F1 25348397 N/A physical interaction ComPPI
PKNOX1 APP 25348397 N/A physical interaction ComPPI
PKNOX1 MOV10 25348397 N/A physical interaction ComPPI
PKNOX1 VPS33A 25348397 N/A physical interaction ComPPI
PKNOX1 VPS16 25348397 N/A physical interaction ComPPI
PKNOX1 SAR1B 25348397 N/A physical interaction ComPPI
PKNOX1 CCDC120 25348397 N/A physical interaction ComPPI
PKNOX1 VWA5A 25348397 N/A physical interaction ComPPI
PKNOX1 ACOT7 25348397 N/A physical interaction ComPPI
PKNOX1 C5ORF24 25348397 N/A physical interaction ComPPI
PKNOX1 NUP58 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PKNOX1 FAM110B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXB7 PKNOX1 14525934 25348397 27898060 9366523 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
PKNOX1 PAX6 20413611 27898060 stimulant N/A OmniPath
PKNOX1 HOXA1 27898060 9582372 stimulant N/A OmniPath

Visualization










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