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GENE：GINS4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GINS4
FullNmae GINS complex subunit 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28226
EnsembleID ENSG00000147536
Uniprot Q9BRT9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GINS4 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GINS4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GINS4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GINS4 GO:0000727,GO:0000811,GO:0000811,GO:0001833,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0006268,GO:0006268,GO:0071162,GO:0071162

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GINS4 GINS1 16531994 17102137 17116885 17296725 17417653 17582221 17652513 18451105 19158510 19223333 19793801 26192618 interaction type N/A ACSN
GINS4 GINS3 16531994 17102137 17116885 17296725 17417653 17582221 17652513 18451105 19158510 19223333 19793801 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR GINS4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 GINS4 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 GINS4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GINS4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 GINS4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GINS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GINS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GINS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GINS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 GINS4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002075FA GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB GINS4 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005030C1 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001F8FF2 GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B GINS4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD GINS4 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GINS1 GINS4 25361965 interaction type N/A PTMCode2
GINS4 GINS1 25361965 interaction type N/A PTMCode2
GINS2 GINS4 25361965 interaction type N/A PTMCode2
GINS4 GINS2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1R13B GINS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX4 GINS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CD2BP2 GINS4 25348397 N/A physical interaction ComPPI
LDHB GINS4 25348397 N/A physical interaction ComPPI
MCM5 GINS4 25348397 N/A physical interaction ComPPI
CSNK1G2 GINS4 25348397 N/A physical interaction ComPPI
CTNNBIP1 GINS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R2B GINS4 25348397 N/A physical interaction ComPPI
LAGE3 GINS4 25348397 N/A physical interaction ComPPI
POLA1 GINS4 25348397 N/A physical interaction ComPPI
YWHAZ GINS4 25348397 N/A physical interaction ComPPI
RPA1 GINS4 24126761 24234451 25348397 association tandem affinity purification ComPPI,IntAct
POLE GINS4 25348397 N/A physical interaction ComPPI
PDHA1 GINS4 25348397 N/A physical interaction ComPPI
GRK5 GINS4 25348397 N/A physical interaction ComPPI
RPA2 GINS4 24126761 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RPA3 GINS4 24126761 24234451 25348397 association tandem affinity purification ComPPI,IntAct
POLD1 GINS4 25348397 N/A physical interaction ComPPI
GTF2E2 GINS4 25348397 N/A physical interaction ComPPI
IGBP1 GINS4 25348397 N/A physical interaction ComPPI
CDC45 GINS4 19805216 24234451 25348397 N/A physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
SRSF9 GINS4 25348397 N/A physical interaction ComPPI
SSRP1 GINS4 25348397 N/A physical interaction ComPPI
H2AX GINS4 25348397 N/A physical interaction ComPPI
MCM3 GINS4 25348397 N/A physical interaction ComPPI
DMAP1 GINS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R2 GINS4 25348397 N/A physical interaction ComPPI
TIPIN GINS4 25348397 N/A physical interaction ComPPI
NCDN GINS4 25348397 N/A physical interaction ComPPI
SIK1 GINS4 25348397 N/A physical interaction ComPPI
MCM7 GINS4 25348397 N/A physical interaction ComPPI
DUSP13 GINS4 25348397 N/A physical interaction ComPPI
MCMBP GINS4 22540012 24234451 24299456 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAICS GINS4 25348397 N/A physical interaction ComPPI
ASL GINS4 25348397 N/A physical interaction ComPPI
GINS2 GINS4 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
GINS4 GINS3 25348397 N/A physical interaction ComPPI
GINS4 GINS1 17417653 17652513 24234451 25348397 physical association cosedimentation in solution,molecular sieving,x-ray crystallography,physical interaction,ion exchange chromatography ComPPI,IntAct
GINS4 AHCYL1 25348397 N/A physical interaction ComPPI
GINS4 PPIL3 25348397 N/A physical interaction ComPPI
GINS4 PRDX5 25348397 N/A physical interaction ComPPI
GINS4 IKBKG 25348397 N/A physical interaction ComPPI
GINS4 NUDCD2 25348397 N/A physical interaction ComPPI
GINS4 WDHD1 25348397 N/A physical interaction ComPPI
GINS4 DUSP13 25348397 N/A physical interaction ComPPI
GINS4 LZIC 25348397 N/A physical interaction ComPPI
GINS4 TOX2 25348397 N/A physical interaction ComPPI
GINS4 AMTN 25348397 N/A physical interaction ComPPI
GINS4 BIN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GINS4 LHX8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GINS4 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
DCPS GINS4 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00008B2661 GINS4 27087310 direct interaction,inhibition N/A NPInter

Visualization










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