Gene Information gene info

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GENE：HELLS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HELLS
FullNmae helicase, lymphoid specific
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4861
EnsembleID ENSG00000119969
Uniprot Q9NRZ9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HELLS mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HELLS autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HELLS apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HELLS GO:0000775,GO:0001655,GO:0001822,GO:0003682,GO:0004386,GO:0005515,GO:0005524,GO:0005634,GO:0005721,GO:0005721,GO:0006306,GO:0006346,GO:0006346,GO:0006915,GO:0007049,GO:0016787,GO:0031508,GO:0031508,GO:0044027,GO:0046651,GO:0046651,GO:0051301,GO:0140658,GO:1990830,GO:2001243

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 HELLS 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 HELLS 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HELLS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HELLS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HELLS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HELLS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HELLS 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 HELLS 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 HELLS 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D HELLS 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004E008F HELLS 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 HELLS 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000040780F HELLS 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 HELLS 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 HELLS 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L HELLS 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CIAO1 HELLS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VCP HELLS 25348397 N/A physical interaction ComPPI
H2BC4 HELLS 25348397 N/A physical interaction ComPPI
EMC2 HELLS 25348397 N/A physical interaction ComPPI
FOXG1 HELLS 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
VAPA HELLS 25348397 N/A physical interaction ComPPI
PDGFRB HELLS 25348397 N/A physical interaction ComPPI
NTRK1 HELLS 25348397 N/A physical interaction ComPPI
PVR HELLS 25348397 N/A physical interaction ComPPI
HSPA5 HELLS 25348397 N/A physical interaction ComPPI
MYC HELLS 17314511 17353931 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
F9 HELLS 25348397 N/A physical interaction ComPPI
CBX4 HELLS 25348397 N/A physical interaction ComPPI
EGFR HELLS 25348397 N/A physical interaction ComPPI
HDAC2 HELLS 25348397 N/A physical interaction ComPPI
H3C1 HELLS 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRIM25 HELLS 25348397 N/A physical interaction ComPPI
CD79B HELLS 25348397 N/A physical interaction ComPPI
DNMT3B HELLS 25348397 N/A physical interaction ComPPI
WDR5 HELLS 25348397 N/A physical interaction ComPPI
C3AR1 HELLS 25348397 N/A physical interaction ComPPI
FBL HELLS 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPAP3 HELLS 25348397 N/A physical interaction ComPPI
NEDD1 HELLS 25348397 N/A physical interaction ComPPI
DNMT1 HELLS 25348397 N/A physical interaction ComPPI
H2BC11 HELLS 25348397 N/A physical interaction ComPPI
FOXA3 HELLS 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
APP HELLS 25348397 N/A physical interaction ComPPI
HDAC1 HELLS 25348397 N/A physical interaction ComPPI
GCN1 HELLS 25348397 N/A physical interaction ComPPI
E2F3 HELLS 22157815 24234451 25348397 association,physical association pull down,physical interaction ComPPI,IntAct
RPAP2 HELLS 25348397 N/A physical interaction ComPPI
HELLS FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HELLS LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
HELLS DNMT1 17967891 27898060 stimulant N/A OmniPath
HELLS DNMT3L 17967891 27898060 stimulant N/A OmniPath
HELLS HOXC6 20161795 27898060 inhibition N/A OmniPath
HELLS HOXC8 20161795 27898060 inhibition N/A OmniPath

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