Gene Information gene info

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GENE：MYBL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYBL2
FullNmae MYB proto-oncogene like 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7548
EnsembleID ENSG00000101057
Uniprot P10244

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYBL2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYBL2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYBL2 GO:0000278,GO:0000978,GO:0000978,GO:0000981,GO:0001228,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0031523,GO:0043525,GO:0045944,GO:0045944,GO:0090307,GO:1990830,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYBL2 hsa:4605 path:hsa04218 Cellular senescence - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYBL2 PLA2G4A 14769798 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 MYBL2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 MYBL2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 MYBL2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 MYBL2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MYBL2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 MYBL2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC MYBL2 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 MYBL2 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MYBL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MYBL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYBL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MYBL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MYBL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MYBL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MYBL2 14618416 16299810 trascriptional regulation,stimulation inferred by curator TFlink
MYBL2 MYBL2 15922873 trascriptional regulation,stimulation inferred by curator TFlink
MYCN MYBL2 21304178 trascriptional regulation,stimulation inferred by curator TFlink
SP1 MYBL2 15922873 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 MYBL2 15922873 trascriptional regulation,stimulation inferred by curator TFlink
TFDP1 MYBL2 14618416 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C770D MYBL2 20623644 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr miRSponge
URS00001DE669 MYBL2 21187425 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00001C770D MYBL2 20623644 25416803 27292025 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip TarBase
URS00000BE495 MYBL2 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS000017EA6A MYBL2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005CF5F MYBL2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MYBL2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 MYBL2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000014F13C MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002394F5 MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003B59DF MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000030F801 MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045ED38 MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027F5F3 MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001CE046 MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000334286 MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001F373E MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AD2AA MYBL2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 MYBL2 22135298 phosphorylation N/A PhosphoSite
MYBL2 CCND1 25361965 interaction type N/A PTMCode2
CCND1 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 CCNA1 25361965 interaction type N/A PTMCode2
CCNA1 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 CCNE1 25361965 interaction type N/A PTMCode2
CCNE1 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 CDK2 25361965 interaction type N/A PTMCode2
CDK2 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 CCNA2 25361965 interaction type N/A PTMCode2
CCNA2 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 LIN37 25361965 interaction type N/A PTMCode2
LIN37 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 ZNF622 25361965 interaction type N/A PTMCode2
ZNF622 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 LIN9 25361965 interaction type N/A PTMCode2
LIN9 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 RBBP4 25361965 interaction type N/A PTMCode2
RBBP4 MYBL2 25361965 interaction type N/A PTMCode2
MYBL2 NLK 25361965 interaction type N/A PTMCode2
NLK MYBL2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CCND1 MYBL2 10645009 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
LIN37 MYBL2 17531812 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB9 MYBL2 25348397 N/A physical interaction ComPPI
MAP1LC3B MYBL2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D4 MYBL2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NLK MYBL2 25348397 N/A physical interaction ComPPI
TTF2 MYBL2 12927788 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SND1 MYBL2 11259168 25348397 27898060 N/A in vitro ComPPI,OmniPath
CREBBP MYBL2 11423988 14525934 16055500 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
EP300 MYBL2 11733503 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
FLNA MYBL2 25348397 N/A physical interaction ComPPI
MYBL2 PARP1 10744766 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MYBL2 NCOR2 25348397 N/A in vitro,in vivo ComPPI
MYBL2 NCOR1 11997503 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MYBL2 SKP2 10871850 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MYBL2 CCNA1 11264176 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MYBL2 ZNF622 12645566 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
MYBL2 CDK9 10656684 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MYBL2 CDK2 10095772 10593981 14525934 25348397 9840932 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MYBL2 RBL1 12439743 12947099 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MYBL2 CCNA2 10871850 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MYBL2 CCNE1 14525934 25348397 9012818 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MYBL2 LIN9 14525934 17159899 17531812 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
MYBL2 CDKN1C 25348397 N/A physical interaction ComPPI
MYBL2 E2F1 25348397 N/A physical interaction ComPPI
MYBL2 E2F3 17159899 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBL2 TRIM15 25348397 N/A physical interaction ComPPI
MYBL2 HIPK2 25348397 N/A physical interaction ComPPI
MYBL2 LIN54 17531812 19725879 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBL2 LIN52 17531812 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBL2 RBBP4 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
MYBL2 SPTA1 25348397 N/A physical interaction ComPPI
MYBL2 CLTC 25348397 N/A physical interaction ComPPI
MYBL2 SPTBN1 25348397 N/A physical interaction ComPPI
MYBL2 CLTA 25348397 N/A physical interaction ComPPI
MYBL2 CXCR4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MYBL2 UBE2D3 25348397 N/A physical interaction ComPPI
MYBL2 EWSR1 25348397 N/A physical interaction ComPPI
MYBL2 CTDSPL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBL2 NUF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBL2 PPP2R3C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBL2 ZSCAN26 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYBL2 TEAD2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MYBL2 CCNF 25348397 25557911 27898060 N/A physical interaction ComPPI,OmniPath
MYBL2 FOXM1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MYBL2 PLA2G4A 14769798 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MYBL2 EPAS1 25348397 N/A physical interaction ComPPI
MYBL2 E2F4 17159899 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MYBL2 HDAC2 17159899 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
MAPK6 MYBL2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDC34 MYBL2 10871850 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LZTR1 MYBL2 25348397 N/A physical interaction ComPPI
UBB MYBL2 10871850 14525934 N/A experimental interaction detection HPRD
MYBL2 MYBL2 10544265 14525934 N/A experimental interaction detection,two hybrid HPRD
H1-4 MYBL2 24234451 30021884 physical association cross-linking study IntAct
H1-5 MYBL2 24234451 30021884 physical association cross-linking study IntAct
MYBL2 BIN2 23169658 27898060 N/A N/A OmniPath
CDK2 MYBL2 10095772 10593981 11264176 20068231 27898060 9840932 stimulant N/A OmniPath
E2F1 MYBL2 16299810 27898060 inhibition,stimulant N/A OmniPath
MYBL2 CDK1 15510213 27898060 stimulant N/A OmniPath
E2F4 MYBL2 17159899 27898060 8334989 inhibition N/A OmniPath
MYBL2 CCNB1 15510213 27898060 stimulant N/A OmniPath
CSNK2A1 MYBL2 11522824 27898060 N/A N/A OmniPath

Visualization










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