GENE：AMD1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AMD1 |
| FullNmae | adenosylmethionine decarboxylase 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:457 |
| EnsembleID | ENSG00000123505 |
| Uniprot | P17707 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AMD1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| AMD1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AMD1 | GO:0004014,GO:0004014,GO:0005515,GO:0005829,GO:0005829,GO:0006595,GO:0006597,GO:0008295,GO:0019810,GO:0042802 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AMD1 | hsa:262 | path:hsa00270 | Cysteine and methionine metabolism - Homo sapiens (human) |
| AMD1 | hsa:262 | path:hsa00330 | Arginine and proline metabolism - Homo sapiens (human) |
| AMD1 | hsa:262 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | AMD1 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | AMD1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | AMD1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| MYC | AMD1 | 12695333 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | AMD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETV4 | AMD1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| JUN | AMD1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000021D7C8 | AMD1 | 20371350 23824327 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS000005481D | AMD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | AMD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000008C563 | AMD1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001383CF | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ECFE5 | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000246356 | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EBD4B | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002AA55A | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000025EABA | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001AFC71 | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000028BB8 | AMD1 | 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | AMD1 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | AMD1 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | AMD1 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | AMD1 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020CEC2 | AMD1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | AMD1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B0E50 | AMD1 | 23313552 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000037E170 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005E1A16 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122ED0 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032EF64 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237CBD | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000B1C9 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A07C1 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000324096 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | AMD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000568FF8 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000021202F | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | AMD1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BCD9C | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E96DA | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000610EFA | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000019F055 | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E6EFA | AMD1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BMP7 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| SHC1 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| DOK3 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| POMC | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| ADCYAP1 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| CLEC11A | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| HSPB1 | AMD1 | 24234451 25277244 25348397 | physical association | reverse ras recruitment system,physical interaction | ComPPI,IntAct |
| SSX2 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| FBXO4 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| POP4 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| MED4 | AMD1 | 25348397 | N/A | physical interaction | ComPPI |
| AMD1 | BMP15 | 25348397 | N/A | physical interaction | ComPPI |
| AMD1 | KPTN | 25348397 | N/A | physical interaction | ComPPI |
| AMD1 | MISP | 25348397 | N/A | physical interaction | ComPPI |
| AMD1 | SHC4 | 25348397 | N/A | physical interaction | ComPPI |