GENE：CD55
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CD55 |
| FullNmae | CD55 molecule (Cromer blood group) |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2665 |
| EnsembleID | ENSG00000196352 |
| Uniprot | P08174 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CD55 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CD55 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CD55 | GO:0000139,GO:0001618,GO:0002726,GO:0005515,GO:0005576,GO:0005886,GO:0005886,GO:0006958,GO:0007204,GO:0008289,GO:0009986,GO:0030133,GO:0030449,GO:0030667,GO:0031664,GO:0033116,GO:0045087,GO:0045121,GO:0045730,GO:0045916,GO:0045916,GO:0046718,GO:0070062,GO:0098552,GO:0101003,GO:1903659,GO:2000516,GO:2000563 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CD55 | hsa:1604 | path:hsa04610 | Complement and coagulation cascades - Homo sapiens (human) |
| CD55 | hsa:1604 | path:hsa04640 | Hematopoietic cell lineage - Homo sapiens (human) |
| CD55 | hsa:1604 | path:hsa05416 | Viral myocarditis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | CD55 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | CD55 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CD55 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | CD55 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | CD55 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | CD55 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CD55 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CD55 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREB1 | CD55 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000028BB8 | CD55 | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AF715 | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003EB4CF | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042B108 | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010BD8D | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000259AE4 | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000202460 | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020579D | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | CD55 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | CD55 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007FBA | CD55 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002233F4 | CD55 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | CD55 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | CD55 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000308E4D | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040FA88 | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000057A7C | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A79D1 | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005194EC | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000204177 | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001938D9 | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | CD55 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B59A2 | CD55 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CCD18 | CD55 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | CD55 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000049FAE8 | CD55 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CD55 | LCK | 25361965 | interaction type | N/A | PTMCode2 |
| LCK | CD55 | 25361965 | interaction type | N/A | PTMCode2 |
| CD55 | FYN | 25361965 | interaction type | N/A | PTMCode2 |
| FYN | CD55 | 25361965 | interaction type | N/A | PTMCode2 |
| CD14 | CD55 | 25361965 | interaction type | N/A | PTMCode2 |
| CD55 | CD14 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GNAI3 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| LCK | CD55 | 1385527 14525934 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
| GPLD1 | CD55 | 14525934 25348397 27898060 7512501 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| PICALM | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| SYNJ2BP | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| FYN | CD55 | 1385527 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| ATP6V1E1 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| PTRH2 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| NDUFS7 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| S100A10 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| TIMM50 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | CR1 | 11694537 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| CD55 | CD14 | 11745332 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CD55 | ADGRE5 | 10540231 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CD55 | NDUFB7 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | MPV17 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | MAN2A1 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | RAB31 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | PTCD3 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | SLC2A1 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | INF2 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | ZMPSTE24 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | SLC12A4 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | SLC25A24 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | CHI3L1 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | C6ORF120 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | C2 | 25348397 | N/A | physical interaction | ComPPI |
| MRPL4 | CD55 | 25348397 | N/A | physical interaction | ComPPI |
| CD55 | CD55 | 12499389 14525934 | N/A | experimental interaction detection | HPRD |
| CD55 | ADGRE5 | 10540231 12417446 27898060 | stimulant | N/A | OmniPath |
| CD14 | CD55 | 11745332 27898060 | N/A | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B078E | CD55 | 27087310 | direct interaction,inhibition | N/A | NPInter |