GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
CDK10 |
| FullNmae |
cyclin dependent kinase 10 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:1770 |
| EnsembleID |
ENSG00000185324 |
| Uniprot |
Q15131 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| CDK10 |
mitotic_cd |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
| CDK10 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| CDK10 |
GO:0004674,GO:0004674,GO:0004693,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005737,GO:0006468,GO:0007089,GO:0007346,GO:0008285,GO:0018107,GO:0030030,GO:0032956,GO:0036064,GO:0043410,GO:0106310,GO:1902018 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
CDK10 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| YBX1 |
CDK10 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| CTCF |
CDK10 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
CDK10 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
CDK10 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
CDK10 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| TRIM28 |
CDK10 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS000055128B |
CDK10 |
19826008
25416803
|
mrna cleavage,inhibition |
array technology,rna immunoprecipitation,quantitative reverse transcription pcr |
TarBase |
| URS00000F4AC3 |
CDK10 |
16822819
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| CDK10 |
ETS2 |
22135298
25361965
|
interaction type,phosphorylation |
N/A |
PhosphoSite,PTMCode2 |
| ETS2 |
CDK10 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| PIN1 |
CDK10 |
22158035
24234451
25348397
27898060
|
physical association |
anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction |
ComPPI,IntAct,OmniPath |
| HSPA8 |
CDK10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| LRATD2 |
CDK10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ACTB |
CDK10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HSP90AB1 |
CDK10 |
22939624
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,luminescence based mammalian interactome mapping |
ComPPI,IntAct |
| RNF115 |
CDK10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ETS2 |
CDK10 |
18242510
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,in vitro,in vivo |
ComPPI,IntAct |
| SEMG2 |
CDK10 |
23602568
24234451
25348397
|
physical association |
physical interaction,tandem affinity purification |
ComPPI,IntAct |
| PRKD2 |
CDK10 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| ACTA2 |
CDK10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CCT2 |
CDK10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CDK10 |
MGMT |
25348397
|
N/A |
physical interaction |
ComPPI |
| CDK10 |
PLS1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CDK10 |
RNASEH2A |
25348397
|
N/A |
physical interaction |
ComPPI |
| CDK10 |
ACTBL2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CDK10 |
CCNQ |
24218572
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
| CCR4 |
CDK10 |
24234451
28298427
|
physical association |
ubiquitin reconstruction |
IntAct |
| CDK10 |
ETS2 |
11313931
18242510
24218572
27898060
|
N/A |
N/A |
OmniPath |
Visualization