Gene Information gene info

GENE:DCP1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DCP1A
FullNmae decapping mRNA 1A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18714
EnsembleID ENSG00000272886
Uniprot Q9NPI6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DCP1A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DCP1A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DCP1A GO:0000184,GO:0000290,GO:0000932,GO:0000932,GO:0003729,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0008047,GO:0016020,GO:0019894,GO:0031087,GO:0036464,GO:0042802,GO:0110156,GO:0140933,GO:1903608

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DCP1A hsa:55802 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 DCP1A 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 DCP1A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DCP1A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 DCP1A 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 DCP1A 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D DCP1A 17968323 17991735 18270520 18372920 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 DCP1A 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004AF715 DCP1A 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032835F DCP1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 DCP1A 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000753AD DCP1A 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS0000008A99 DCP1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001FC26E DCP1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 DCP1A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000058276F DCP1A 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS0000080D0A DCP1A 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK8 DCP1A 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
DDX6 DCP1A 16364915 19966221 24234451 25036637 25348397 26496610 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
EDC3 DCP1A 16364915 19966221 24234451 25036637 25348397 26496610 27107012 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,two hybrid array,fluorescence microscopy,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
TRAF6 DCP1A 25348397 N/A physical interaction ComPPI
YWHAG DCP1A 25348397 N/A in vivo ComPPI
SMAD4 DCP1A 15231748 24234451 25348397 25609649 27107012 association,physical association two hybrid,physical interaction,in vitro,in vivo,tandem affinity purification,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
DDX17 DCP1A 21876179 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A PNRC2 15604093 19150429 23085078 24234451 25348397 25416956 27898060 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,molecular sieving,x-ray crystallography,physical interaction,ion exchange chromatography,two hybrid array,confocal microscopy,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
DCP1A TTF2 12927788 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DCP1A LSM8 15231747 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DCP1A DCP2 12417715 15231747 16364915 19966221 23085078 24234451 25036637 25348397 26496610 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,fluorescence microscopy,in vitro ComPPI,IntAct
DCP1A AGO1 25348397 N/A in vivo ComPPI
DCP1A AGO2 25348397 N/A in vivo ComPPI
DCP1A UPF1 12417715 16364915 19150429 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,in vivo,confocal microscopy ComPPI,IntAct
DCP1A USP4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A MAPK8 25348397 N/A physical interaction ComPPI
DCP1A PAXIP1 25348397 N/A physical interaction ComPPI
DCP1A HSPA1L 25348397 N/A physical interaction ComPPI
DCP1A EDC4 16364915 19966221 24234451 25036637 25348397 26496610 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
DCP1A ZFP36 16364915 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A DCP1B 16364915 19966221 24234451 25036637 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
DCP1A XRN1 16364915 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
DCP1A AASS 25348397 N/A physical interaction ComPPI
DCP1A BAG4 24234451 25036637 25348397 26496610 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy,luminescence based mammalian interactome mapping ComPPI,IntAct
DCP1A EIF2B4 25348397 N/A physical interaction ComPPI
DCP1A KANK2 25348397 N/A physical interaction ComPPI
DCP1A PFKM 25348397 N/A physical interaction ComPPI
DCP1A PNRC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A TRIP13 25348397 N/A physical interaction ComPPI
DCP1A MAPK3 25348397 N/A physical interaction ComPPI
DCP1A FHL2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DCP1A RITA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DCP1A PIM1 25348397 N/A physical interaction ComPPI
DCP1A NTRK1 25348397 N/A physical interaction ComPPI
DCP1A BTRC 25348397 N/A physical interaction ComPPI
DCP1A XPO1 25348397 N/A physical interaction ComPPI
DCP1A MAP2K1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A TBX3 25348397 N/A physical interaction ComPPI
DCP1A MARF1 25348397 N/A physical interaction ComPPI
DCP1A TRMT6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A CLTC 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A CRKL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A PPP1R35 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A PATL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A PPP1R37 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A NSMAF 24234451 25348397 26133670 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
DCP1A DUSP18 25348397 N/A physical interaction ComPPI
DCP1A CCDC59 25348397 N/A physical interaction ComPPI
DCP1A KCTD3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DCP1A KIF13B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DCP1A ZBTB21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DCP1A TRIM25 25348397 N/A physical interaction ComPPI
DCP1A ZC3HAV1 21876179 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A YWHAZ 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
DCP1A TIA1 20412057 24234451 24965446 25348397 colocalization fluorescence microscopy ComPPI,IntAct
DCP1A HAX1 23164465 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
DCP1A RAD52 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DCP1A PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
DCP1A GSK3B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CBY1 DCP1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ALDH18A1 DCP1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCP1A DCP1A 16364915 19966221 24234451 association,physical association anti tag coimmunoprecipitation,molecular sieving,nuclear magnetic resonance,static light scattering,x-ray crystallography,fluorescence microscopy IntAct
MAPK8 DCP1A 21859862 23300942 27898060 N/A N/A OmniPath

Visualization