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GENE：ETS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ETS2
FullNmae ETS proto-oncogene 2, transcription factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3489
EnsembleID ENSG00000157557
Uniprot P15036

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ETS2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ETS2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ETS2 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0001501,GO:0001712,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0005886,GO:0006357,GO:0007498,GO:0019904,GO:0030154,GO:0035259,GO:0045944,GO:0061629,GO:0061629,GO:0090009,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ETS2 hsa:2114 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
ETS2 hsa:2114 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PTEN ETS2 10753747 11747822 12040186 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523 26192618 interaction type N/A ACSN
ETS2 MMP9 19847259 23977064 26192618 interaction type N/A ACSN
ETS2 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
ETS2 TLR9 15294971 23180781 physical association electrophoretic mobility shift assay InnateDB
ETS2 GFI1 16287849 23180781 physical association anti tag coimmunoprecipitation InnateDB
ERG ETS2 23180781 9681824 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR ETS2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ETS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ETS2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC ETS2 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ETS2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PGR ETS2 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ETS2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ETS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ERF ETS2 7588608 trascriptional regulation,stimulation inferred by curator TFlink
ETV7 ETS2 22615925 trascriptional regulation,stimulation inferred by curator TFlink
JUN ETS2 22354960 trascriptional regulation,stimulation inferred by curator TFlink
ETV4 ETS2 N/A trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 ETS2 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 ETS2 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A ETS2 N/A trascriptional regulation,stimulation inferred by curator TFlink
TP53 ETS2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D ETS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D ETS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E ETS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000052E1A6 ETS2 22298639 25416803 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000AD002 ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B ETS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 ETS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000B0E50 ETS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C ETS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB ETS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 ETS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 ETS2 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAMK2A ETS2 22135298 phosphorylation N/A PhosphoSite
CDK10 ETS2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RAF1 ETS2 25361965 interaction type N/A PTMCode2
ETS2 RAF1 25361965 interaction type N/A PTMCode2
SMARCA4 ETS2 25361965 interaction type N/A PTMCode2
ETS2 SMARCA4 25361965 interaction type N/A PTMCode2
FOS ETS2 25361965 interaction type N/A PTMCode2
ETS2 FOS 25361965 interaction type N/A PTMCode2
ETS2 JUN 25361965 interaction type N/A PTMCode2
JUN ETS2 25361965 interaction type N/A PTMCode2
ETS2 GATA3 25361965 interaction type N/A PTMCode2
GATA3 ETS2 25361965 interaction type N/A PTMCode2
ETS2 PAX8 25361965 interaction type N/A PTMCode2
PAX8 ETS2 25361965 interaction type N/A PTMCode2
ETS2 CDK10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZFYVE9 ETS2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ETS2 SMARCA4 12637547 25348397 27898060 N/A in vitro ComPPI,OmniPath
ETS2 TDP2 12743594 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ETS2 SRC 14525934 15788656 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ETS2 NCOR1 14525934 15788656 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ETS2 CREBBP 10358095 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ETS2 GATA3 10212281 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ETS2 NR3C1 11279115 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ETS2 POU5F1 11689681 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
ETS2 ETS1 14525934 25348397 9334186 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ETS2 JUN 14525934 25348397 9334186 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ETS2 EP300 10942770 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ETS2 CDK10 18242510 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,in vitro,in vivo ComPPI,IntAct
ETS2 STAT5B 10815800 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ETS2 ZMYND11 12894593 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
ETS2 SPI1 25348397 N/A physical interaction ComPPI
ETS2 FOS 25348397 N/A physical interaction ComPPI
ETS2 ERG 14525934 25348397 9334186 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
ETS2 NCOA3 25348397 N/A physical interaction ComPPI
ETS2 TP53 18374905 24234451 25348397 26331536 26871468 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
ETS2 XPO1 25348397 N/A physical interaction ComPPI
ETS2 SRA1 25348397 N/A physical interaction ComPPI
ETS2 TWIST1 18598946 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 COP1 24234451 25117710 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 NCOA1 25348397 N/A physical interaction ComPPI
ETS2 EWSR1 25348397 N/A physical interaction ComPPI
ETS2 VPS51 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 CTDP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 GTF3C5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 IMPACT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 MRPL14 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 ANKS6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 DET1 25348397 N/A physical interaction ComPPI
ETS2 NFKB2 24234451 25348397 26389665 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 CCNQ 24218572 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
TWIST2 ETS2 18598946 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETS2 ETS2 14525934 9334186 N/A experimental interaction detection,two hybrid HPRD
PLK1 ETS2 11027273 12095911 12511603 27898060 N/A N/A OmniPath
CAMK2A ETS2 19182667 25117710 27898060 inhibition N/A OmniPath
CDK10 ETS2 11313931 18242510 24218572 27898060 N/A N/A OmniPath

Visualization










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