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GENE：GPAA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPAA1
FullNmae glycosylphosphatidylinositol anchor attachment 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4446
EnsembleID ENSG00000197858
Uniprot O43292

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPAA1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPAA1 GO:0003923,GO:0005515,GO:0005739,GO:0005783,GO:0005789,GO:0005789,GO:0005813,GO:0005829,GO:0006621,GO:0015631,GO:0016020,GO:0016255,GO:0016255,GO:0016255,GO:0034235,GO:0042765,GO:0042765,GO:0042765,GO:0042765,GO:0065003

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GPAA1 hsa:8733 path:hsa00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Homo sapiens (human)
GPAA1 hsa:8733 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 GPAA1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GPAA1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GPAA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GPAA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GPAA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PIN1 GPAA1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ATP5F1B GPAA1 25348397 N/A physical interaction ComPPI
ALPP GPAA1 12616539 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
YIPF3 GPAA1 25348397 N/A physical interaction ComPPI
EIF3E GPAA1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DPEP1 GPAA1 25348397 N/A physical interaction ComPPI
PTGIR GPAA1 25348397 N/A physical interaction ComPPI
ARF6 GPAA1 25348397 N/A physical interaction ComPPI
VNN2 GPAA1 25348397 N/A physical interaction ComPPI
GRIK5 GPAA1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GPAA1 LPAR1 25348397 N/A physical interaction ComPPI
GPAA1 NDUFS1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GPAA1 ACAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AQP2 GPAA1 25348397 N/A physical interaction ComPPI
AGTR1 GPAA1 24234451 28298427 physical association ubiquitin reconstruction IntAct

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