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GENE：HOXA10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HOXA10
FullNmae homeobox A10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5100
EnsembleID ENSG00000253293
Uniprot P31260

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HOXA10 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HOXA10 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HOXA10 GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001501,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005667,GO:0005737,GO:0006357,GO:0007283,GO:0007338,GO:0008584,GO:0009952,GO:0009954,GO:0030326,GO:0030850,GO:0033574,GO:0042826,GO:0043627,GO:0045944,GO:0060065,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HOXA10 hsa:3206 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HOXA10 HDAC2 14512427 23180781 physical association anti tag coimmunoprecipitation InnateDB
HOXA10 PBX1 14512427 23180781 physical association anti tag coimmunoprecipitation InnateDB
CYBB HOXA10 10766757 23180781 physical association electrophoretic mobility supershift assay InnateDB
FGF2 HOXA10 22493287 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 HOXA10 17311863 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
ESR2 HOXA10 17311863 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
HOXA10 HOXA10 16580301 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
HOXA11 HOXA10 17688409 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 HOXA10 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HOXA10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HOXA10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HOXA10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR HOXA10 15905361 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREBBP HOXA10 16849538 trascriptional regulation,stimulation inferred by curator TFlink
GZF1 HOXA10 16049025 trascriptional regulation,stimulation inferred by curator TFlink
WT1 HOXA10 23888944 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000315338 HOXA10 20981674 rna interference,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000B59A2 HOXA10 19074876 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000029D9F1 HOXA10 18308931 \N rna interference,inhibition array technology,western blot,miRNA interference luciferase reporter assay miRSponge
URS000029D9F1 HOXA10 18308931 18927107 25416803 mrna cleavage,inhibition array technology,western blot miR2Disease,TarBase
URS00000B59A2 HOXA10 19074876 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000315338 HOXA10 20981674 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F31F4 HOXA10 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00003CF1AD HOXA10 23622248 25416803 26741129 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clash,miRNA interference luciferase reporter assay TarBase
URS00001C770D HOXA10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000052E1A6 HOXA10 24222951 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,immunohistochemistry TarBase
URS00001B341F HOXA10 20371350 21572407 23246964 23446348 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000007FBA HOXA10 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA HOXA10 20371350 21572407 23446348 24057258 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00000C5BAA HOXA10 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 HOXA10 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 HOXA10 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 HOXA10 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 HOXA10 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 HOXA10 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A HOXA10 20371350 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000070B1D HOXA10 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000002CF68 HOXA10 20371350 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000535FDD HOXA10 20371350 21572407 23446348 25416803 25500095 26701625 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00002FC5B0 HOXA10 20371350 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000AB32B HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D HOXA10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F HOXA10 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 HOXA10 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C5969 HOXA10 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000010BD8D HOXA10 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F HOXA10 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SPI1 HOXA10 25361965 interaction type N/A PTMCode2
HOXA10 SPI1 25361965 interaction type N/A PTMCode2
HOXA10 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 HOXA10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GMNN HOXA10 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FOXB1 HOXA10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PTPN6 HOXA10 12145285 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN11 HOXA10 25348397 N/A genetic ComPPI
NFATC1 HOXA10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SPI1 HOXA10 14525934 18692240 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CREBBP HOXA10 11585930 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EP300 HOXA10 11585930 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
COPS5 HOXA10 25348397 N/A physical interaction ComPPI
MAPK14 HOXA10 25348397 N/A physical interaction ComPPI
KAT2B HOXA10 25348397 N/A physical interaction ComPPI
MYC HOXA10 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
POLR3D HOXA10 25348397 N/A physical interaction ComPPI
SIRT2 HOXA10 14525934 15213244 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
FOXE1 HOXA10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM25 HOXA10 25348397 N/A physical interaction ComPPI
TEAD2 HOXA10 25348397 N/A physical interaction ComPPI
MEIS1 HOXA10 14525934 25348397 9343407 N/A experimental interaction detection,in vitro ComPPI,HPRD
PBX1 HOXA10 12145285 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SNAPC1 HOXA10 25348397 N/A physical interaction ComPPI
ARIH1 HOXA10 25348397 N/A physical interaction ComPPI
GNG13 HOXA10 25348397 N/A two hybrid ComPPI
FOXO1 HOXA10 12493691 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RBPJ HOXA10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HOXA10 EMX1 25348397 N/A physical interaction ComPPI
HOXA10 HOXA10 12145285 14525934 N/A experimental interaction detection HPRD
HOXA10 FOXO1 12493691 18391971 27898060 stimulant N/A OmniPath
PTPN6 HOXA10 12145285 27898060 N/A N/A OmniPath
PTPN11 HOXA10 19022774 27898060 stimulant N/A OmniPath
MAPK4 HOXA10 12145285 27898060 N/A N/A OmniPath

Visualization










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