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GENE：IL24

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL24
FullNmae interleukin 24
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11346
EnsembleID ENSG00000162892
Uniprot Q13007

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL24 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IL24 GO:0005125,GO:0005515,GO:0005576,GO:0005615,GO:0006915,GO:0007165,GO:0008284,GO:0008285,GO:0030336,GO:0042531,GO:0071222,GO:0071353

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL24 hsa:11009 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IL24 hsa:11009 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
IL24 hsa:11009 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL20RB IL24 11706020 23180781 physical association saturation binding InnateDB
MACROH2A1 IL24 23180781 24752897 physical association anti tag coimmunoprecipitation InnateDB
PELP1 IL24 23180781 24752897 physical association anti tag coimmunoprecipitation InnateDB
IL24 IL22RA1 17208301 23331499 stimulation N/A SignaLink,SignaLink
IL24 IL20RA 17208301 23331499 stimulation N/A SignaLink,SignaLink
IL24 IL20RB 17208301 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR IL24 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 IL24 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TFAP2C IL24 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 IL24 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
EGR1 IL24 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IL24 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF IL24 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPB IL24 10942517 trascriptional regulation,stimulation inferred by curator TFlink
JUN IL24 21357535 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004DA9DB IL24 22917968 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000016914 IL24 20737563 23212344 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000016914 IL24 20737563 23212344 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004DA9DB IL24 22917968 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
KRAS IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SMAD4 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HRAS IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXW7 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CLU IL24 25348397 N/A physical interaction ComPPI
PIK3CA IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
APC IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PARP1 IL24 24234451 25348397 25640309 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CASP8 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAD51 IL24 24234451 25348397 25640309 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ATM IL24 24234451 25348397 25640309 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CCR5 IL24 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CHEK2 IL24 24234451 25348397 25640309 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTEN IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BAG4 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NOTCH2 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RB1CC1 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HMMR IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ESR2 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AKT1 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL20RA IL24 25348397 N/A in vivo ComPPI
IL24 RARG 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL24 DCD 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL24 LSP1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL24 PALB2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL24 IFNB1 18511292 27898060 stimulant N/A OmniPath
IL24 IL20RA 11706020 17208301 27898060 stimulant N/A OmniPath
IL24 IL20RB 11706020 17208301 27898060 stimulant N/A OmniPath
IL24 IL22RA1 17208301 27898060 stimulant N/A OmniPath

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