GENE:KANK1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | KANK1 |
| FullNmae | KN motif and ankyrin repeat domains 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:19309 |
| EnsembleID | ENSG00000107104 |
| Uniprot | Q14678 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| KANK1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| KANK1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| KANK1 | GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005856,GO:0005886,GO:0005886,GO:0008013,GO:0008283,GO:0010977,GO:0030036,GO:0030177,GO:0030336,GO:0030837,GO:0030837,GO:0032587,GO:0035023,GO:0035024,GO:0046627,GO:0090263,GO:0090303,GO:0090521,GO:1900025,GO:1900028,GO:2000114,GO:2000393 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | KANK1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | KANK1 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | KANK1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| HIF1A | KANK1 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | KANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | KANK1 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000016D2D4 | KANK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001A405B | KANK1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001EFEC1 | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | KANK1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171020 | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | KANK1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DYNLL1 | KANK1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ENO1 | KANK1 | 25348397 | N/A | physical interaction | ComPPI |
| PPP1CA | KANK1 | 14525934 15231748 22321011 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| GRK5 | KANK1 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAQ | KANK1 | 18458160 19559006 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation,pull down | ComPPI,IntAct,OmniPath |
| ARRB2 | KANK1 | 25348397 | N/A | physical interaction | ComPPI |
| EPB41L3 | KANK1 | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ARFGEF1 | KANK1 | 22084092 24234451 25348397 27898060 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct,OmniPath |
| CTNNB1 | KANK1 | 16968744 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct,OmniPath |
| BAIAP2 | KANK1 | 14525934 19171758 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,in vivo,confocal microscopy | ComPPI,HPRD,IntAct |
| TRIM25 | KANK1 | 25348397 | N/A | physical interaction | ComPPI |
| SHMT2 | KANK1 | 25348397 | N/A | physical interaction | ComPPI |
| PIP4K2A | KANK1 | 25348397 | N/A | physical interaction | ComPPI |
| KANK1 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| KANK1 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| KANK1 | KIF21A | 19559006 22084092 24234451 25348397 26496610 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| KANK1 | WASF2 | 19171758 24234451 25348397 | physical association | confocal microscopy | ComPPI,IntAct |
| KANK1 | BCAR1 | 24234451 25348397 28007913 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| H1-1 | KANK1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
