GENE:KDM6B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | KDM6B |
| FullNmae | lysine demethylase 6B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29012 |
| EnsembleID | ENSG00000132510 |
| Uniprot | O15054 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| KDM6B | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| KDM6B | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| KDM6B | GO:0000978,GO:0002437,GO:0005515,GO:0005634,GO:0005654,GO:0006338,GO:0007507,GO:0008013,GO:0010468,GO:0014823,GO:0021766,GO:0031490,GO:0032452,GO:0044666,GO:0045165,GO:0045446,GO:0045944,GO:0046872,GO:0048333,GO:0055007,GO:0060992,GO:0070301,GO:0071557,GO:0071558,GO:0071558,GO:0120162 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | KDM6B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | KDM6B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | KDM6B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | KDM6B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | KDM6B | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000021D7C8 | KDM6B | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS000035CC3E | KDM6B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007340 | KDM6B | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002394F5 | KDM6B | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000365675 | KDM6B | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077DDE | KDM6B | 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C403E | KDM6B | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D6C3F | KDM6B | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000156390 | KDM6B | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000008B558 | KDM6B | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D5391 | KDM6B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDE70 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D35D9 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005485E8 | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000002103A | KDM6B | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002EF20A | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFBE3 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076995 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000272A3D | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000221168 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000035D2F9 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000017EA6A | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F507C | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AAA0 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000045147B | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | KDM6B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F0C23 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000008A99 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003BBF48 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000521626 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000000C73C | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000055128B | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002004E0 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000005481D | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001597DC | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004818BD | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FFA8C | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003ACE11 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BE495 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DC1D3 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003EB4CF | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000045ED38 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000027F5F3 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759B6A | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000334286 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F373E | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000027464B | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E728C | KDM6B | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| WAS | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| TK1 | KDM6B | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| SMAD4 | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| SMAD1 | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| SMAD2 | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| TDG | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| SMAD3 | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| ASH2L | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| RBBP5 | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| SOX2 | KDM6B | 22801502 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| KLF4 | KDM6B | 22801502 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| H3C1 | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| ESR1 | KDM6B | 21841772 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct,OmniPath |
| CSNK2B | KDM6B | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| WDR5 | KDM6B | 25348397 | N/A | physical interaction | ComPPI |
| H1-2 | KDM6B | 24234451 30021884 | physical association | cross-linking study | IntAct |
| KDM6B | H3C1 | 20123895 27898060 | stimulant | N/A | OmniPath |
