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GENE：PHLDA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PHLDA1
FullNmae pleckstrin homology like domain family A member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8933
EnsembleID ENSG00000139289
Uniprot Q8WV24

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PHLDA1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PHLDA1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PHLDA1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PHLDA1 GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005829,GO:0006915,GO:0031410,GO:0043065,GO:0045210,GO:1901981

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PHLDA1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PHLDA1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PHLDA1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PHLDA1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PHLDA1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PHLDA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EWSR1 PHLDA1 22323082 trascriptional regulation,stimulation inferred by curator TFlink
FLI1 PHLDA1 22323082 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 PHLDA1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00004AF715 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000016FD1A PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006FDD4 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004DA9DB PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BA274 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000003ABC4 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001EB3 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000475586 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004B4B85 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C1E1 PHLDA1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKA PHLDA1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MAD2L2 PHLDA1 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
KRTAP4-12 PHLDA1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MDFI PHLDA1 14525934 16189514 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLSCR1 PHLDA1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PABPC4 PHLDA1 11369516 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
EGFR PHLDA1 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HSPA4 PHLDA1 14525934 17024176 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HSPB1 PHLDA1 25348397 N/A physical interaction ComPPI
ELAVL1 PHLDA1 25348397 N/A physical interaction ComPPI
DNAJB1 PHLDA1 25348397 N/A physical interaction ComPPI
EIF3D PHLDA1 11369516 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PHLDA1 HSPA4L 14525934 17024176 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PHLDA1 APP 25348397 N/A physical interaction ComPPI
PHLDA1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RPL14 PHLDA1 11369516 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PHLDA1 F2RL1 24234451 28298427 physical association ubiquitin reconstruction IntAct
AURKA PHLDA1 21807936 27898060 N/A N/A OmniPath

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