Gene Information gene info

GENE:POU2F1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POU2F1
FullNmae POU class 2 homeobox 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9212
EnsembleID ENSG00000143190
Uniprot P14859

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POU2F1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POU2F1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
POU2F1 GO:0000785,GO:0000978,GO:0000978,GO:0000978,GO:0000979,GO:0000981,GO:0000981,GO:0000981,GO:0001228,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005783,GO:0006357,GO:0043231,GO:0043565,GO:0045892,GO:0045944,GO:0045944,GO:0045944,GO:0090575,GO:1902895

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POU2F1 hsa:5451 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
POU2F1 hsa:5451 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
STAT5A POU2F1 14645506 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
STAT5B POU2F1 14645506 23180781 physical association gst pull down InnateDB
CCND1 POU2F1 14645506 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
IRF3 POU2F1 11724783 23180781 physical association electrophoretic mobility shift assay InnateDB
CFTR POU2F1 17696881 23180781 physical association electrophoretic mobility supershift assay InnateDB
POU2F1 LYN 1508184 23180781 physical association electrophoretic mobility shift assay InnateDB
CXCR5 POU2F1 14993281 23180781 physical association electrophoretic mobility shift assay InnateDB
PKNOX1 POU2F1 15138251 23180781 physical association pull down InnateDB
PBX1 POU2F1 15138251 23180781 physical association pull down InnateDB
CSF2 POU2F1 16498406 23180781 physical association anti tag coimmunoprecipitation InnateDB
POU2F1 IL3 16498406 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL2 POU2F1 16498406 23180781 physical association anti tag coimmunoprecipitation InnateDB
POU2F1 IL5 12354764 23180781 physical association electrophoretic mobility supershift assay InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 POU2F1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 POU2F1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 POU2F1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 POU2F1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A POU2F1 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
FOXP3 POU2F1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 POU2F1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 POU2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PPARG POU2F1 12881480 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 POU2F1 23172665 trascriptional regulation,stimulation inferred by curator TFlink
USF1 POU2F1 18845576 trascriptional regulation,stimulation inferred by curator TFlink
USF2 POU2F1 18845576 trascriptional regulation,stimulation inferred by curator TFlink
AR POU2F1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 POU2F1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 POU2F1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000B59A2 POU2F1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 POU2F1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 POU2F1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000005481D POU2F1 22012620 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000041CB9C POU2F1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001270D3 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000134ADC POU2F1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0B46 POU2F1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 POU2F1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 POU2F1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D POU2F1 22100165 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C POU2F1 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 POU2F1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F5B39 POU2F1 25416803 26375440 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004719AB POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008B558 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 POU2F1 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 POU2F1 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B POU2F1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A POU2F1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000458AD2 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000035AC91 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009C45F POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 POU2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 POU2F1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E POU2F1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 POU2F1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 POU2F1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB POU2F1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC POU2F1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 POU2F1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 POU2F1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001B968D POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000544FF1 POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A POU2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 POU2F1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000482389 POU2F1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 POU2F1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000016FD1B POU2F1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000015B295 POU2F1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000298BA3 POU2F1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000272039 POU2F1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000054DF42 POU2F1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 POU2F1 22135298 phosphorylation N/A PhosphoSite
PRKDC POU2F1 22135298 phosphorylation N/A PhosphoSite
CDK2 POU2F1 22135298 phosphorylation N/A PhosphoSite
PRKAB1 POU2F1 22135298 phosphorylation N/A PhosphoSite
NR3C1 POU2F1 25361965 interaction type N/A PTMCode2
POU2F1 NR3C1 25361965 interaction type N/A PTMCode2
POU2F1 SOX2 25361965 interaction type N/A PTMCode2
SOX2 POU2F1 25361965 interaction type N/A PTMCode2
POU2F1 NFYA 25361965 interaction type N/A PTMCode2
NFYA POU2F1 25361965 interaction type N/A PTMCode2
POU2F1 CREB1 25361965 interaction type N/A PTMCode2
CREB1 POU2F1 25361965 interaction type N/A PTMCode2
HNF1A POU2F1 25361965 interaction type N/A PTMCode2
POU2F1 HNF1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSPA8 POU2F1 25348397 N/A physical interaction ComPPI
RARA POU2F1 25348397 N/A physical interaction ComPPI
HOXC4 POU2F1 25348397 N/A physical interaction ComPPI
PRR20E POU2F1 25348397 N/A physical interaction ComPPI
PRR20C POU2F1 25348397 N/A physical interaction ComPPI
PRR20D POU2F1 25348397 N/A physical interaction ComPPI
SP4 POU2F1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FOXC2 POU2F1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SP1 POU2F1 10976766 19070619 24234451 25348397 27898060 8668525 9525610 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
TBP POU2F1 25348397 N/A coimmunoprecipitation,physical interaction,physical interaction,biochemical,in vitro,in vivo ComPPI
PRKDC POU2F1 25348397 N/A physical interaction ComPPI
NFYA POU2F1 25348397 N/A in vivo ComPPI
HCFC1 POU2F1 10629049 24234451 25348397 27898060 8454622 9889203 physical association coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
AR POU2F1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
HMGA1 POU2F1 25348397 N/A physical interaction ComPPI
VDR POU2F1 25348397 N/A physical interaction ComPPI
PRKACA POU2F1 25348397 N/A physical interaction ComPPI
THRA POU2F1 25348397 N/A physical interaction,in vivo ComPPI
NCOR2 POU2F1 11134019 19617623 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
GAPDH POU2F1 25348397 N/A physical interaction ComPPI
PARP1 POU2F1 25348397 27898060 9537509 N/A two hybrid,physical interaction,in vitro ComPPI,OmniPath
XRCC5 POU2F1 25348397 N/A physical interaction ComPPI
STIP1 POU2F1 25348397 N/A physical interaction ComPPI
STAT5A POU2F1 25348397 N/A in vitro,in vivo ComPPI
STAT5B POU2F1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
XRCC6 POU2F1 25348397 N/A physical interaction,in vitro ComPPI
HMGB2 POU2F1 25348397 N/A in vitro,in vivo ComPPI
TNF POU2F1 25348397 N/A physical interaction ComPPI
RELA POU2F1 12019209 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
MNAT1 POU2F1 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
SPTBN1 POU2F1 25348397 N/A physical interaction ComPPI
SOX2 POU2F1 14559893 25348397 27898060 N/A in vitro ComPPI,OmniPath
LMNB1 POU2F1 21897860 23580612 25348397 27898060 N/A physical interaction ComPPI,OmniPath
POGZ POU2F1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TLE5 POU2F1 25348397 N/A two hybrid,in vitro ComPPI
CEBPE POU2F1 25348397 N/A physical interaction ComPPI
PLK3 POU2F1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FGB POU2F1 25348397 N/A physical interaction ComPPI
NR3C1 POU2F1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SNAPC4 POU2F1 11056176 11856838 25348397 27898060 9418884 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
BARD1 POU2F1 25348397 N/A in vivo ComPPI
BRD7 POU2F1 25348397 N/A physical interaction ComPPI
TRIM25 POU2F1 25348397 N/A physical interaction ComPPI
POU2AF1 POU2F1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
ESR1 POU2F1 25348397 N/A physical interaction,in vivo ComPPI
TXNRD1 POU2F1 25348397 N/A physical interaction ComPPI
TLX2 POU2F1 25348397 N/A physical interaction ComPPI
BRCA1 POU2F1 25348397 N/A physical interaction,in vitro ComPPI
PGR POU2F1 25348397 N/A physical interaction,in vivo ComPPI
TEAD2 POU2F1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PKNOX1 POU2F1 25348397 N/A physical interaction ComPPI
HOXB13 POU2F1 25348397 N/A physical interaction ComPPI
PBX1 POU2F1 25348397 N/A physical interaction ComPPI
CDK11B POU2F1 25348397 N/A physical interaction ComPPI
BCE1 POU2F1 25348397 N/A in vitro ComPPI
HNF1A POU2F1 10779377 25348397 27898060 N/A in vitro ComPPI,OmniPath
POU2F1 MSX1 25348397 N/A in vitro ComPPI
POU2F1 FDXR 25348397 N/A in vitro,in vivo ComPPI
POU2F1 LIFR 25348397 N/A in vitro ComPPI
POU2F1 NPAT 25348397 N/A physical interaction,in vivo ComPPI
POU2F1 RXRA 25348397 N/A physical interaction ComPPI
POU2F1 HDAC1 25348397 N/A physical interaction ComPPI
POU2F1 IRF9 25348397 N/A physical interaction ComPPI
POU2F1 CREB1 12391146 25348397 27898060 N/A physical interaction ComPPI,OmniPath
POU2F1 CDK11A 25348397 N/A physical interaction ComPPI
POU2F1 APP 25348397 N/A physical interaction ComPPI
POU2F1 MAGEA10 25348397 N/A physical interaction ComPPI
POU2F1 FOXC1 25348397 N/A physical interaction ComPPI
POU2F1 FOXS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
POU2F1 TEAD1 24234451 25348397 8423815 N/A pull down ComPPI,IntAct
HOXC9 POU2F1 25348397 N/A physical interaction ComPPI
POU2F1 POU2F1 24234451 25416956 physical association two hybrid array IntAct
PRKCA POU2F1 1684878 27898060 N/A N/A OmniPath
GAPDH POU2F1 12887926 27898060 stimulant N/A OmniPath
POU2F1 H2BC11 12887926 27898060 stimulant N/A OmniPath
STAT5A POU2F1 14645506 27898060 N/A N/A OmniPath
PER2 POU2F1 23836662 27898060 inhibition N/A OmniPath
CDK7 POU2F1 27898060 9368058 N/A N/A OmniPath
POU2F1 STAT5B 14645506 27898060 N/A N/A OmniPath
STAT5B POU2F1 14645506 27898060 N/A N/A OmniPath
PRKDC POU2F1 14612514 17213819 27898060 9368058 inhibition N/A OmniPath
PRKAA1 POU2F1 1684878 27898060 9368058 inhibition N/A OmniPath
POU2AF1 POU2F1 10541551 11380252 12727885 27898060 9418884 stimulant N/A OmniPath

Visualization