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GENE：SRSF7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SRSF7
FullNmae serine and arginine rich splicing factor 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10789
EnsembleID ENSG00000115875
Uniprot Q16629

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SRSF7 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SRSF7 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SRSF7 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SRSF7 GO:0000398,GO:0003723,GO:0003729,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006397,GO:0008270,GO:0008380,GO:0016607,GO:0019904,GO:0048025,GO:0051028,GO:0070062,GO:1990830

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SRSF7 hsa:6432 path:hsa03040 Spliceosome - Homo sapiens (human)
SRSF7 hsa:6432 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
SRSF7 hsa:6432 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SREK1 SRSF7 14559993 23180781 physical association pull down InnateDB
SRSF7 HNF1A 18160415 23180781 physical association anti tag coimmunoprecipitation InnateDB
EZH2 SRSF7 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 SRSF7 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
EED SRSF7 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SRPK1 SRSF7 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB
SRPK2 SRSF7 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 SRSF7 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SRSF7 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A SRSF7 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 SRSF7 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SRSF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SRSF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SRSF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SRSF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC SRSF7 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFEC1 SRSF7 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00004505E4 SRSF7 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002C0FCB SRSF7 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000096022 SRSF7 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000007FBA SRSF7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB SRSF7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B SRSF7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SRSF7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 SRSF7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA SRSF7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000004CA3 SRSF7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003CF1AD SRSF7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015D23B SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C0D3F SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004959F4 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 SRSF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 SRSF7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F SRSF7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 SRSF7 22473208 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000065D58 SRSF7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000019907A SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000137EDE SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027352D SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D4175 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003FBC84 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006372A SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C SRSF7 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VASN SRSF7 25348397 N/A physical interaction ComPPI
SNW1 SRSF7 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL5 SRSF7 25348397 N/A physical interaction ComPPI
CDC5L SRSF7 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 SRSF7 25348397 N/A physical interaction ComPPI
DDX21 SRSF7 25348397 N/A physical interaction ComPPI
IFIT3 SRSF7 21642987 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 SRSF7 25348397 N/A physical interaction ComPPI
SH3KBP1 SRSF7 25348397 N/A physical interaction ComPPI
SNRPA1 SRSF7 25348397 N/A physical interaction ComPPI
CDK6 SRSF7 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
GABARAPL2 SRSF7 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
U2AF1L5 SRSF7 25348397 N/A physical interaction ComPPI
MAP1LC3B SRSF7 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EZH2 SRSF7 25348397 N/A physical interaction ComPPI
SF3A2 SRSF7 17332742 24234451 25348397 physical association affinity chromatography technology,physical interaction ComPPI,IntAct
JUN SRSF7 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX9 SRSF7 25348397 N/A physical interaction ComPPI
COPS5 SRSF7 25348397 N/A physical interaction ComPPI
RBM39 SRSF7 25348397 N/A physical interaction ComPPI
RBBP6 SRSF7 18624398 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
SFPQ SRSF7 25348397 N/A physical interaction ComPPI
PRKACA SRSF7 22677170 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
U2AF2 SRSF7 25348397 N/A physical interaction ComPPI
PAXIP1 SRSF7 25348397 N/A physical interaction ComPPI
NTRK1 SRSF7 25348397 N/A physical interaction ComPPI
ENO1 SRSF7 25348397 N/A physical interaction ComPPI
SREK1 SRSF7 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
PPP1CA SRSF7 25348397 N/A physical interaction ComPPI
HNRNPU SRSF7 25348397 N/A physical interaction ComPPI
CLK1 SRSF7 25348397 N/A physical interaction ComPPI
TM9SF2 SRSF7 25348397 N/A physical interaction ComPPI
EWSR1 SRSF7 25348397 N/A physical interaction ComPPI
RELA SRSF7 25348397 N/A physical interaction ComPPI
SDCBP SRSF7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XPO1 SRSF7 25348397 N/A physical interaction ComPPI
SRSF1 SRSF7 25348397 N/A physical interaction ComPPI
ZRANB2 SRSF7 25348397 N/A physical interaction ComPPI
SRPK1 SRSF7 23602568 24234451 25348397 phosphorylation reaction,association physical interaction,protein kinase assay,tandem affinity purification ComPPI,IntAct
NEDD8 SRSF7 25348397 N/A physical interaction ComPPI
CUL2 SRSF7 25348397 N/A physical interaction ComPPI
CUL4B SRSF7 25348397 N/A physical interaction ComPPI
SON SRSF7 25348397 N/A physical interaction ComPPI
CDK2 SRSF7 25348397 N/A physical interaction ComPPI
CUL1 SRSF7 25348397 N/A physical interaction ComPPI
SEPTIN2 SRSF7 25348397 N/A physical interaction ComPPI
YWHAE SRSF7 25348397 N/A physical interaction ComPPI
SF3A1 SRSF7 25348397 N/A physical interaction ComPPI
GABARAP SRSF7 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF3I SRSF7 25348397 N/A physical interaction ComPPI
MAP1LC3A SRSF7 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SF1 SRSF7 24234451 25348397 26420826 association anti bait coimmunoprecipitation ComPPI,IntAct
SRSF11 SRSF7 25348397 N/A physical interaction ComPPI
EED SRSF7 25348397 N/A physical interaction ComPPI
TRA2B SRSF7 25348397 N/A physical interaction ComPPI
CUL7 SRSF7 25348397 N/A physical interaction ComPPI
H3C1 SRSF7 25348397 N/A physical interaction ComPPI
CAND1 SRSF7 25348397 N/A physical interaction ComPPI
NEDD4 SRSF7 25348397 N/A physical interaction ComPPI
PRPF6 SRSF7 25348397 N/A physical interaction ComPPI
SRSF3 SRSF7 25348397 N/A physical interaction ComPPI
SRSF9 SRSF7 25348397 N/A physical interaction ComPPI
BARD1 SRSF7 25348397 N/A physical interaction ComPPI
HNRNPF SRSF7 25348397 N/A physical interaction ComPPI
PCBP2 SRSF7 25348397 N/A two hybrid,in vivo ComPPI
SRPK2 SRSF7 23602568 24234451 25348397 phosphorylation reaction,association physical interaction,protein kinase assay,tandem affinity purification ComPPI,IntAct
CCNL2 SRSF7 25348397 N/A in vivo ComPPI
ILF2 SRSF7 25348397 N/A physical interaction ComPPI
SRSF5 SRSF7 25348397 N/A physical interaction ComPPI
ESR1 SRSF7 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
SNU13 SRSF7 25348397 N/A physical interaction ComPPI
SAFB SRSF7 25348397 N/A physical interaction ComPPI
EIF3D SRSF7 25348397 N/A physical interaction ComPPI
MAGOH SRSF7 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALYREF SRSF7 25348397 N/A physical interaction ComPPI
SRSF7 DUSP11 25348397 N/A two hybrid,physical interaction ComPPI
SRSF7 CDK19 25348397 N/A physical interaction,in vivo ComPPI
SRSF7 CDK11A 25348397 N/A two hybrid,in vivo ComPPI
SRSF7 CPSF6 25348397 N/A in vitro,in vivo ComPPI
SRSF7 RNPS1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRSF7 HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SRSF7 NXF1 15184380 17036044 24234451 25348397 physical association coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SRSF7 HNRNPA1 25348397 N/A physical interaction ComPPI
SRSF7 SF3B3 25348397 N/A physical interaction ComPPI
SRSF7 U2AF1 25348397 N/A physical interaction ComPPI
SRSF7 SF3B6 25348397 N/A physical interaction ComPPI
SRSF7 LUC7L3 25348397 N/A physical interaction ComPPI
SRSF7 PRPF3 25348397 N/A physical interaction ComPPI
SRSF7 SART1 25348397 N/A physical interaction ComPPI
SRSF7 BUD31 25348397 N/A physical interaction ComPPI
SRSF7 USP39 25348397 N/A physical interaction ComPPI
SRSF7 MSH2 25348397 N/A physical interaction ComPPI
SRSF7 GTF3C1 25348397 N/A physical interaction ComPPI
SRSF7 TRIM55 25348397 N/A physical interaction ComPPI
SRSF7 NFIA 25348397 N/A physical interaction ComPPI
SRSF7 SEPTIN7 25348397 N/A physical interaction ComPPI
SRSF7 STT3B 25348397 N/A physical interaction ComPPI
SRSF7 S100A9 25348397 N/A physical interaction ComPPI
SRSF7 SURF4 25348397 N/A physical interaction ComPPI
SRSF7 TFPI 25348397 N/A physical interaction ComPPI
SRSF7 HP1BP3 25348397 N/A physical interaction ComPPI
SRSF7 HNF1A 25348397 N/A physical interaction ComPPI
SRSF7 PAN2 25348397 N/A physical interaction ComPPI
SRSF7 CLK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SRSF7 TARDBP 25348397 N/A physical interaction ComPPI
SRSF7 ZBTB1 25348397 N/A physical interaction ComPPI
SRSF7 STAU1 25348397 N/A physical interaction ComPPI
SRSF7 CEP250 25348397 N/A physical interaction ComPPI
SRSF7 LUC7L2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SRSF7 MOV10 25348397 N/A physical interaction ComPPI
SRSF7 OBSL1 25348397 N/A physical interaction ComPPI
SRSF7 SUZ12 25348397 N/A physical interaction ComPPI
SRSF7 LUZP4 25348397 N/A physical interaction ComPPI
SRSF7 TRA2A 25348397 N/A physical interaction ComPPI
SRSF7 SRSF6 25348397 N/A physical interaction ComPPI
SRSF7 HSF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SRSF7 MZT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SRSF7 GAN 25348397 N/A physical interaction ComPPI
SRSF7 DYNC2I1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
SRSF7 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SRSF7 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SRSF7 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
SRRM1 SRSF7 25348397 N/A physical interaction ComPPI
EIF4A3 SRSF7 23084401 23085716 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IK SRSF7 25348397 N/A physical interaction ComPPI
PRPF38A SRSF7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDX41 SRSF7 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
METTL14 SRSF7 24234451 29507755 association anti tag coimmunoprecipitation IntAct
L1TD1 SRSF7 24234451 25702638 association anti bait coimmunoprecipitation IntAct
SRSF7 NXF1 15184380 15210956 17036044 18364396 22658674 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AED36 SRSF7 27087310 direct interaction,inhibition N/A NPInter

Visualization










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