GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
TGIF2 |
FullNmae |
TGFB induced factor homeobox 2 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:15764 |
EnsembleID |
ENSG00000118707 |
Uniprot |
Q9GZN2 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
TGIF2 |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
TGIF2 |
GO:0000122,GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0001227,GO:0003700,GO:0005634,GO:0005654,GO:0005654,GO:0005813,GO:0006355,GO:0010470,GO:0035881,GO:0038092,GO:1902871,GO:1990837 |
KEGG Annotation:
GeneSymbol |
GeneID |
Pathway |
Pathway Name |
TGIF2 |
hsa:60436 |
path:hsa04350 |
TGF-beta signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
TGIF2 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
YBX1 |
TGIF2 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
TFAP2C |
TGIF2 |
20629094
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
PRDM14 |
TGIF2 |
18971253
20953172
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TRIM28 |
TGIF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HDAC4 |
TGIF2 |
17610967
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00003BBF48 |
TGIF2 |
18768788
\N
|
rna interference,inhibition |
western blot,miRNA interference luciferase reporter assay |
miRSponge |
URS00003BBF48 |
TGIF2 |
18768788
18927107
25416803
26638007
|
mrna cleavage,inhibition |
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
miR2Disease,TarBase |
URS00001C770D |
TGIF2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS0000239117 |
TGIF2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS00000EED18 |
TGIF2 |
25416803
26464633
28078014
|
mrna cleavage,inhibition |
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
URS0000272A3D |
TGIF2 |
25416803
28160548
|
mrna cleavage,inhibition |
nucleotide sequence identification,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
URS0000136174 |
TGIF2 |
22291592
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000000EF0B |
TGIF2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003E226A |
TGIF2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000012930C |
TGIF2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000015188E |
TGIF2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002CE0C6 |
TGIF2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002C7B2B |
TGIF2 |
25416803
26722295
|
mrna cleavage,inhibition |
experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
URS0000076E54 |
TGIF2 |
25416803
27448300
|
mrna cleavage,inhibition |
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
URS0000435A77 |
TGIF2 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
SMAD3 |
TGIF2 |
11427533
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vivo |
ComPPI,HPRD |
TARBP2 |
TGIF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
RBBP8 |
TGIF2 |
25348397
|
N/A |
in vivo |
ComPPI |
TRIM25 |
TGIF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ELAVL1 |
TGIF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TGIF2 |
HDAC1 |
11427533
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction |
ComPPI,HPRD |
TGIF2 |
H3-4 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
Visualization