Gene Information gene info

GENE:VANGL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VANGL1
FullNmae VANGL planar cell polarity protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15512
EnsembleID ENSG00000173218
Uniprot Q8TAA9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VANGL1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VANGL1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
VANGL1 GO:0005515,GO:0005886,GO:0016328,GO:0043473,GO:0060071

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VANGL1 hsa:81839 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SRPK1 VANGL1 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR VANGL1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR2 VANGL1 19376833 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 VANGL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 VANGL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 VANGL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 VANGL1 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 VANGL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 VANGL1 20584899 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000B59A2 VANGL1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 VANGL1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 VANGL1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 VANGL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D VANGL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031B6ED VANGL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000209F04 VANGL1 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C VANGL1 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075D50C VANGL1 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F VANGL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 VANGL1 20371350 21572407 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000058DCD8 VANGL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000045E0EC VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001EB9FC VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 VANGL1 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CELSR3 VANGL1 25361965 interaction type N/A PTMCode2
VANGL1 CELSR3 25361965 interaction type N/A PTMCode2
CELSR1 VANGL1 25361965 interaction type N/A PTMCode2
VANGL1 CELSR1 25361965 interaction type N/A PTMCode2
CD82 VANGL1 25361965 interaction type N/A PTMCode2
VANGL1 CD82 25361965 interaction type N/A PTMCode2
VANGL1 DVL1 25361965 interaction type N/A PTMCode2
DVL1 VANGL1 25361965 interaction type N/A PTMCode2
DVL2 VANGL1 25361965 interaction type N/A PTMCode2
VANGL1 DVL2 25361965 interaction type N/A PTMCode2
CELSR2 VANGL1 25361965 interaction type N/A PTMCode2
VANGL1 CELSR2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SPRY2 VANGL1 25348397 N/A physical interaction ComPPI
KBTBD7 VANGL1 25348397 N/A physical interaction ComPPI
CD44 VANGL1 25348397 N/A physical interaction ComPPI
CD82 VANGL1 14525934 15205336 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,fluorescence microscopy,two hybrid ComPPI,HPRD,IntAct,OmniPath
ERBB4 VANGL1 25348397 N/A physical interaction ComPPI
SDC2 VANGL1 25348397 N/A physical interaction ComPPI
RASSF9 VANGL1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFRSF1A VANGL1 25348397 N/A physical interaction ComPPI
NXF2 VANGL1 25348397 N/A physical interaction ComPPI
EVC2 VANGL1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RAPGEF5 VANGL1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DVL1 VANGL1 14525934 15456783 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
ZRANB2 VANGL1 25348397 N/A physical interaction ComPPI
SRPK1 VANGL1 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
DVL2 VANGL1 14525934 15456783 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
EPB41L3 VANGL1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SDC1 VANGL1 25348397 N/A physical interaction ComPPI
CREB3 VANGL1 25348397 N/A two hybrid bait and prey pooling approach ComPPI
TRIM25 VANGL1 25348397 N/A physical interaction ComPPI
VANGL2 VANGL1 25348397 N/A physical interaction ComPPI
RNF41 VANGL1 25348397 N/A physical interaction ComPPI
BRAF VANGL1 25348397 N/A physical interaction ComPPI
DVL3 VANGL1 14525934 15456783 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
VANGL1 NT5C3A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
VANGL1 GMFG 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
VANGL1 SMYD3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
VANGL1 THAP2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
VANGL1 FBXW11 25348397 N/A physical interaction ComPPI
VANGL1 CCDC8 25348397 N/A physical interaction ComPPI
VANGL1 LUC7L 25348397 N/A physical interaction ComPPI
VANGL1 RASSF10 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VANGL1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VANGL1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VANGL1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VANGL1 NAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VANGL1 PTPN3 24234451 25348397 28330616 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VANGL1 GPR156 25348397 N/A physical interaction ComPPI
VANGL1 PNN 25348397 N/A physical interaction ComPPI
VANGL1 MANSC1 25348397 N/A physical interaction ComPPI
VANGL1 PRICKLE3 25348397 N/A physical interaction ComPPI
VANGL1 EPB41L5 25348397 N/A physical interaction ComPPI
VANGL1 CD83 25348397 N/A physical interaction ComPPI
VANGL1 JPH4 25348397 N/A physical interaction ComPPI
VANGL1 FGF8 25348397 N/A physical interaction ComPPI
VANGL1 ZC3H18 25348397 N/A physical interaction ComPPI
VANGL1 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VANGL1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VANGL1 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VANGL1 DLG1 24234451 30126976 N/A p8 filamentous phage display IntAct

Visualization