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GENE：IKBKB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IKBKB
FullNmae inhibitor of nuclear factor kappa B kinase subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5960
EnsembleID ENSG00000104365
Uniprot O14920

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IKBKB necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IKBKB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IKBKB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IKBKB apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IKBKB alkaliptosis 33670487 Topological analysis of networks yielded FANCD2 (ferroptosis, negative regulator, down), NCOA4 (ferroptosis, up), IKBKB (alkaliptosis, down), and RHOA (entotic cell death, down) as potential drug targets in colon adenocarcinoma, glioblastoma multiforme, small cell lung cancer phenotypes respectively. retulator signature
IKBKB alkaliptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
IKBKB GO:0002223,GO:0002479,GO:0002755,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006468,GO:0006468,GO:0006954,GO:0007249,GO:0007249,GO:0007249,GO:0008384,GO:0008384,GO:0008384,GO:0008385,GO:0008385,GO:0009615,GO:0009898,GO:0010803,GO:0018105,GO:0018105,GO:0019901,GO:0030866,GO:0033209,GO:0033209,GO:0034138,GO:0035509,GO:0035631,GO:0035666,GO:0038095,GO:0042325,GO:0042802,GO:0042803,GO:0043123,GO:0045087,GO:0045121,GO:0045893,GO:0045944,GO:0045944,GO:0046982,GO:0050852,GO:0051092,GO:0051092,GO:0051092,GO:0051403,GO:0051604,GO:0070498,GO:0070498,GO:0071356,GO:0072659,GO:0097110,GO:0106310,GO:1903140,GO:1903347,GO:1990459

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IKBKB hsa:3551 path:hsa01523 Antifolate resistance - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04210 Apoptosis - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04930 Type II diabetes mellitus - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04931 Insulin resistance - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
IKBKB hsa:3551 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05010 Alzheimer disease - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05131 Shigellosis - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05132 Salmonella infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05135 Yersinia infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05142 Chagas disease - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05160 Hepatitis C - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05161 Hepatitis B - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05162 Measles - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05164 Influenza A - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05200 Pathways in cancer - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05215 Prostate cancer - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05222 Small cell lung cancer - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)
IKBKB hsa:3551 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CHUK IKBKB 12799363 15456791 18949366 21903422 23180781 23430059 26192618 association,physical association affinity chromatography technology,anti tag coimmunoprecipitation ACSN,InnateDB
MCL1 IKBKB 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26192618 26587781 interaction type N/A ACSN
TRAF2 IKBKB 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26192618 26587781 interaction type N/A ACSN
IKBKB SDHC 26192618 interaction type N/A ACSN
IKBKB MAP3K7 10187861 10807933 11325957 11460167 14514672 16301747 16356855 17047224 17496917 19909372 20300203 23180781 29145629 9744859 phosphorylation reaction,enzymatic reaction,physical association anti tag coimmunoprecipitation,inferred by curator,in-gel kinase assay InnateDB,Reactome
IKBKB IRAK1 11096118 18180283 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB SQSTM1 10356400 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PRKCZ 10356400 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB MAP3K14 10713178 11278268 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB MAP3K11 10713178 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IKBKB IKBKB 10807933 12351658 21399639 23180781 24243840 29145629 9891086 phosphorylation reaction,physical association anti tag coimmunoprecipitation,inferred by curator,in-gel kinase assay,protein kinase assay InnateDB,Reactome
IKBKB CTNNB1 11527961 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,gst pull down,in-gel kinase assay InnateDB
NFKBIA IKBKB 10085062 10320352 10527519 10807933 10889159 11158290 11368781 11527961 12429743 15024091 15574499 15856023 16023083 16737960 16818647 16888014 21399639 23180781 9721103 phosphorylation reaction,physical association anti tag coimmunoprecipitation,surface plasmon resonance,in-gel kinase assay,protein kinase assay InnateDB
IKBKB IRS1 12351658 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IKBKB IRS2 12351658 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB FANCA 12210728 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,two hybrid,in-gel kinase assay InnateDB
IKBKB CASP8 11002417 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB NFKB1 10469655 10593898 10723127 10835356 11158290 12482991 14523047 15145317 15337789 15371334 16806191 17047224 17363905 18412279 19754427 22078572 22988300 23180781 23708964 29145629 8601309 9135156 9252186 9315679 9721103 9914500 phosphorylation reaction,enzymatic reaction,physical association anti tag coimmunoprecipitation,inferred by curator,in-gel kinase assay InnateDB,Reactome
IKBKB TANK 12133833 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB MAP3K1 23180781 9819420 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
TNFRSF1A IKBKB 10755617 23180781 23815148 physical association anti tag coimmunoprecipitation InnateDB
IKBKB TRPC4AP 14585990 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
IKBKB PPM1B 14585847 23180781 dephosphorylation reaction,physical association anti tag coimmunoprecipitation,in gel phosphatase assay InnateDB
IKBKB HSPB1 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB HSPD1 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB HSPA1A 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB HSP90AA1 11864612 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB DOK1 15574499 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IKBKB TRIM27 16393995 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
TICAM1 IKBKB 14739303 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB CSF2RA 12637324 17952117 23180781 physical association anti tag coimmunoprecipitation,two hybrid,fluorescent resonance energy transfer InnateDB
IKBKB EIF2AK2 16600570 23180781 physical association gst pull down InnateDB
IKBKB ATM 16497931 23180781 physical association anti tag coimmunoprecipitation InnateDB
STAP2 IKBKB 16365431 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB MAP3K13 12492477 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PRDX3 12492477 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB CDC37 11864612 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB CXCL8 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB BIRC3 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PEBP1 11585904 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PRKCQ 11120819 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB CHUK 10893415 11242109 11325957 11460167 11971985 12221085 12351658 14514672 14695475 15145317 15229184 15456791 16115877 16301747 17047224 17496917 17728323 18462684 19666475 19909372 20300203 20434986 20449947 21903422 23180781 24100029 24369075 29145629 9008162 9689078 9721103 9744859 9751060 9891086 physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
IKBKB YWHAB 16024783 23180781 phosphorylation reaction in-gel kinase assay InnateDB
IKBKB ARRB1 15173580 23180781 physical association anti tag coimmunoprecipitation InnateDB
ARRB2 IKBKB 15173580 23180781 physical association anti tag coimmunoprecipitation InnateDB
DNAJA3 IKBKB 15601829 23180781 physical association gst pull down InnateDB
IKBKB SGK1 15695387 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IKBKB MAVS 18207245 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB NFKBIB 10320352 10593898 10723127 11470788 15084594 17047224 23109003 23180781 29145629 9135156 9315679 9721103 9914500 enzymatic reaction,physical association,chemical activation reaction anti tag coimmunoprecipitation,surface plasmon resonance,inferred by curator InnateDB,Reactome,SignaLink
IKBKB NFKBIE 10320352 23180781 physical association surface plasmon resonance InnateDB
IKBKB TBK1 14560022 21138416 21903422 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay,protein kinase assay InnateDB
IKBKB NLRP2 15456791 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PYCARD 12486103 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PYDC1 12656673 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB REL 10593898 16888014 23180781 29145629 9135156 9315679 9721103 9914500 enzymatic reaction,physical association inferred by curator,in-gel kinase assay InnateDB,Reactome
IKBKB TRAF2 10795740 19150425 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
IKBKB TNFAIP3 17709380 23180781 phosphorylation reaction in-gel kinase assay InnateDB
IKBKB MAP3K3 15572679 23180781 physical association anti tag coimmunoprecipitation InnateDB
LTBR IKBKB 15743811 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB TSC1 17693255 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
MTOR IKBKB 18519641 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB ELP1 23180781 9751059 physical association anti tag coimmunoprecipitation InnateDB
IKBKB NCOA3 11971985 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PLK1 18957422 23180781 phosphorylation reaction protein kinase assay InnateDB
IKBKB NOTCH1 18560356 23180781 physical association anti tag coimmunoprecipitation InnateDB
MLST8 IKBKB 18755269 23180781 physical association anti tag coimmunoprecipitation InnateDB
FLT3 IKBKB 18670883 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB CTNNAL1 17952117 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
IKBKB IKBIP 17952117 23180781 physical association two hybrid InnateDB
IKBKB TP53 19883646 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PPP1CA 18362886 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PPP1R15A 18362886 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB CUEDC2 18362886 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
IKBKB RIPK1 18362886 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB RPS3 21399639 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,protein kinase assay InnateDB
BID IKBKB 21552281 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB NLRX1 21703539 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PYGL 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB FKBP4 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB FKBP5 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB FOXO3 22531926 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG IKBKB 10968790 11583588 12133833 12612076 14743216 15084594 18037881 19820708 20098747 23109003 23180781 24369075 physical association,chemical activation reaction anti tag coimmunoprecipitation,gst pull down,protein array,pull down InnateDB,SignaLink
IKBKB IKBKG 10893415 11325957 11460167 12221085 14514672 14695475 15145317 16115877 16301747 16603398 17047224 17496917 17728323 18462684 19666475 19909372 20300203 20434986 20449947 23180781 24369075 29145629 9008162 9689078 9744859 9751060 physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
IKBKE IKBKB 21138416 23180781 phosphorylation reaction in-gel kinase assay,protein kinase assay InnateDB
RACK1 IKBKB 23180781 24323043 physical association anti tag coimmunoprecipitation,pull down InnateDB
IKBKB CRKL 23180781 24145029 physical association anti tag coimmunoprecipitation InnateDB
SASH1 IKBKB 23180781 23776175 physical association anti tag coimmunoprecipitation InnateDB
IKBKB CARD11 16301747 16356855 19909372 29145629 physical association inferred by curator Reactome
IKBKB BCL10 16301747 16356855 19909372 29145629 physical association inferred by curator Reactome
IKBKB MALT1 16301747 16356855 19909372 29145629 physical association inferred by curator Reactome
IKBKB NFKBIA 10593898 10723127 12791687 15084594 15145317 15371334 17047224 17363905 23109003 29145629 8601309 9135156 9252186 9315679 9346484 9721103 9914500 enzymatic reaction,chemical activation reaction inferred by curator Reactome,SignaLink
NFKBIE IKBKB 10593898 29145629 9135156 9315679 9721103 9914500 enzymatic reaction inferred by curator Reactome
IKBKB RELA 10593898 10723127 14523047 15145317 15337789 15371334 17047224 17363905 18412279 22078572 23708964 29145629 8601309 9135156 9252186 9315679 9721103 9914500 enzymatic reaction inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
AR IKBKB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 IKBKB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 IKBKB 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR IKBKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171525 IKBKB 22569286 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS0000171525 IKBKB 22569286 24755559 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 IKBKB 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000016C318 IKBKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F6E49 IKBKB 24550137 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00002E857A IKBKB 23740840 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00003BBF48 IKBKB 25416803 25630970 mrna cleavage,inhibition array technology,nucleotide sequence identification,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000012A1DD IKBKB 25416803 26433127 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000007D64A IKBKB 25416803 26175947 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000157F5 IKBKB 24297251 direct interaction,mrna cleavage,inhibition experimental interaction detection StarBase

Source Target Pmid Interactiontype Methods Database
PRKAA2 IKBKB 22135298 phosphorylation N/A PhosphoSite
SRC IKBKB 22135298 phosphorylation N/A PhosphoSite
SGK1 IKBKB 22135298 phosphorylation N/A PhosphoSite
PLK1 IKBKB 22135298 phosphorylation N/A PhosphoSite
PRKCE IKBKB 22135298 phosphorylation N/A PhosphoSite
MAP3K14 IKBKB 22135298 phosphorylation N/A PhosphoSite
PRKCA IKBKB 22135298 phosphorylation N/A PhosphoSite
IKBKB CYLD 22135298 phosphorylation N/A PhosphoSite
IKBKB DOK1 22135298 phosphorylation N/A PhosphoSite
IKBKB RELA 22135298 phosphorylation N/A PhosphoSite
IKBKB TP63 22135298 phosphorylation N/A PhosphoSite
IKBKB NFKB1 22135298 phosphorylation N/A PhosphoSite
IKBKB NFKBIA 22135298 phosphorylation N/A PhosphoSite
IKBKB IRF3 22135298 phosphorylation N/A PhosphoSite
IKBKB FOS 22135298 phosphorylation N/A PhosphoSite
IKBKB RELB 22135298 phosphorylation N/A PhosphoSite
IKBKB TSC1 22135298 phosphorylation N/A PhosphoSite
IKBKB TNFRSF1A 22135298 phosphorylation N/A PhosphoSite
IKBKB CDKN2A 22135298 phosphorylation N/A PhosphoSite
IKBKB IKBKG 22135298 phosphorylation N/A PhosphoSite
IKBKB RAPGEF2 22135298 phosphorylation N/A PhosphoSite
IKBKB BBC3 22135298 phosphorylation N/A PhosphoSite
IKBKB IRS1 22135298 phosphorylation N/A PhosphoSite
IKBKB PFKFB3 22135298 phosphorylation N/A PhosphoSite
IKBKB RPS3 22135298 phosphorylation N/A PhosphoSite
IKBKB OPTN 22135298 phosphorylation N/A PhosphoSite
IKBKB BCL10 22135298 phosphorylation N/A PhosphoSite
IKBKB FOXO3 22135298 phosphorylation N/A PhosphoSite
IKBKB REL 22135298 phosphorylation N/A PhosphoSite
IKBKB IRF5 22135298 phosphorylation N/A PhosphoSite
PRKCZ IKBKB 22135298 phosphorylation N/A PhosphoSite
LYN IKBKB 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
TRIM21 IKBKB 25348397 N/A physical interaction ComPPI
HSPA8 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFAIP3 IKBKB 11594795 14525934 24234451 25348397 26649818 phosphorylation reaction experimental interaction detection,phosphorylation reaction,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
ACTG1 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SMARCC1 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MEOX2 IKBKB 25348397 N/A physical interaction ComPPI
TRAF6 IKBKB 21782231 24234451 25348397 colocalization cosedimentation through density gradient,physical interaction ComPPI,IntAct
CALM1 IKBKB 25348397 N/A tandem affinity purification ComPPI
RAN IKBKB 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ROCK1 IKBKB 25348397 N/A physical interaction ComPPI
KEAP1 IKBKB 20600852 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
SMN1 IKBKB 25348397 N/A physical interaction ComPPI
ZC3H12A IKBKB 22037600 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TAB3 IKBKB 25348397 N/A physical interaction ComPPI
HSP90AB1 IKBKB 14525934 14743216 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification,proximity ligation assay ComPPI,HPRD,IntAct
EGLN3 IKBKB 19786027 23732909 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PRKCQ IKBKB 11120819 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCA IKBKB 25348397 N/A physical interaction ComPPI
SRC IKBKB 12707358 14525934 15749833 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PRKCD IKBKB 25348397 N/A physical interaction ComPPI
PRKDC IKBKB 25348397 N/A physical interaction ComPPI
PPP1R15A IKBKB 25348397 N/A physical interaction ComPPI
JUN IKBKB 25348397 N/A physical interaction ComPPI
CREBBP IKBKB 11971985 24234451 25241761 25348397 association,physical association affinity chromatography technology,physical interaction,proximity ligation assay ComPPI,IntAct
NCOA3 IKBKB 11971985 14525934 15383283 16135815 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
HIF1A IKBKB 25348397 N/A physical interaction ComPPI
COPS5 IKBKB 25348397 N/A physical interaction ComPPI
MAPK14 IKBKB 25348397 N/A physical interaction ComPPI
PRKCE IKBKB 25348397 N/A physical interaction ComPPI
GLI1 IKBKB 25348397 N/A physical interaction ComPPI
TWIST1 IKBKB 25348397 N/A physical interaction ComPPI
FLNC IKBKB 25348397 N/A physical interaction ComPPI
FLNA IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CUL3 IKBKB 25348397 N/A physical interaction ComPPI
YWHAB IKBKB 14525934 16024783 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CDKN2A IKBKB 25348397 N/A physical interaction ComPPI
CSF2RA IKBKB 12637324 14525934 24234451 25241761 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vivo,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct
UBC IKBKB 25348397 N/A physical interaction ComPPI
HSP90AA1 IKBKB 11864612 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
FAF1 IKBKB 17684021 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BTRC IKBKB 25348397 N/A physical interaction ComPPI
IRF3 IKBKB 21782231 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
EIF2AK2 IKBKB 10848580 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PARP1 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HSPA5 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PLK1 IKBKB 25348397 N/A physical interaction ComPPI
CASP8 IKBKB 11002417 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IKBKB PRKCZ 10022904 10195894 10779355 14525934 25348397 9689078 N/A experimental interaction detection,in vitro ComPPI,HPRD
IKBKB MAP3K11 10713178 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IKBKB TRAF2 11359906 14525934 21782231 24234451 25241761 25348397 colocalization,physical association cosedimentation through density gradient,experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB MAP3K7 10022904 10195894 10779355 11460167 14525934 17363973 24234451 25348397 9689078 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
IKBKB ELP1 14525934 25348397 9751059 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IKBKB PPM1B 14525934 14585847 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IKBKB TANK 12133833 14525934 24234451 25348397 30561431 association experimental interaction detection,in vivo,virotrap ComPPI,HPRD,IntAct
IKBKB EIF2AK3 10848580 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
IKBKB MAP3K13 12492477 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IKBKB TRAF3IP2 25348397 N/A physical interaction,in vivo ComPPI
IKBKB TRPC4AP 14525934 14585990 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
IKBKB CTNNB1 11527961 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB TNFRSF1A 10755617 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB ACVR1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
IKBKB NFKBIB 14525934 14743216 24234451 25348397 9689078 9721103 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
IKBKB CDC37 11864612 14525934 14743216 21903422 24234451 25036637 25348397 26496610 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
IKBKB NFKB2 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
IKBKB AKT1 10485711 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB PRKCB 12070292 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB NR2C2 12547194 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
IKBKB MAP3K3 11429546 14525934 14743216 24234451 25348397 physical association experimental interaction detection,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
IKBKB TBK1 14525934 14560022 21782231 24234451 25348397 colocalization cosedimentation through density gradient,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
IKBKB PEBP1 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
IKBKB STAP2 14525934 16365431 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
IKBKB FOXO3 14525934 15084260 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB CHUK 11971985 12486103 14525934 14743216 16129692 16286467 16319058 20434986 21903422 24234451 25241761 25348397 25852190 9751060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB IRS1 10722755 11606564 12351658 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IKBKB NFKB1 10469655 11158290 11297557 11976329 12482991 14525934 24234451 25241761 25348397 phosphorylation reaction,physical association experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB RELA 10521409 12842894 14525934 16046471 24234451 25241761 25348397 phosphorylation reaction,physical association experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
IKBKB PRDX3 25348397 N/A physical interaction ComPPI
IKBKB IKBKG 10968790 12657630 14525934 14743216 15749833 16126728 16129692 16319058 16938294 17568778 18266467 18462684 19365808 19666608 19706536 20098747 20368414 20434986 21423167 21903422 23104095 24234451 24618592 25348397 25852190 26496610 30561431 9751060 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,x-ray crystallography,physical interaction,protein kinase assay,tandem affinity purification,virotrap ComPPI,HPRD,IntAct
IKBKB IRAK1 25348397 N/A physical interaction ComPPI
IKBKB FANCA 12210728 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
IKBKB MAP3K1 16286467 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
IKBKB CUEDC2 25348397 N/A physical interaction ComPPI
IKBKB PPP1CA 25348397 N/A physical interaction ComPPI
IKBKB TNF 25348397 N/A physical interaction ComPPI
IKBKB DUSP1 25348397 N/A physical interaction ComPPI
IKBKB TP53 19196987 19883646 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
IKBKB HTT 25348397 N/A physical interaction ComPPI
IKBKB COPS3 25348397 N/A physical interaction ComPPI
IKBKB COPS4 25348397 N/A physical interaction ComPPI
IKBKB COPS7A 25348397 N/A physical interaction ComPPI
IKBKB CUL1 25348397 N/A physical interaction ComPPI
IKBKB ERC1 25348397 N/A physical interaction ComPPI
IKBKB HNRNPU 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
IKBKB TRIM40 25348397 N/A physical interaction ComPPI
IKBKB FKBP4 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB FKBP5 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB PYGL 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB CSNK2B 25348397 N/A physical interaction ComPPI
IKBKB NLRX1 25348397 N/A physical interaction ComPPI
IKBKB MUC1 25348397 N/A physical interaction ComPPI
IKBKB TP63 25348397 N/A physical interaction ComPPI
IKBKB HOMER3 20693425 25348397 27898060 N/A physical interaction ComPPI,OmniPath
IKBKB IKBKE 25348397 N/A physical interaction ComPPI
IKBKB RIPK1 25348397 N/A physical interaction ComPPI
IKBKB USP4 25348397 N/A physical interaction ComPPI
IKBKB BRAP 25348397 N/A physical interaction ComPPI
IKBKB TNIP2 24234451 25348397 30561431 association physical interaction,virotrap ComPPI,IntAct
IKBKB PPP2R3C 25348397 N/A physical interaction ComPPI
IKBKB NLRP2 25348397 N/A physical interaction ComPPI
IKBKB HSP90AA2P 25348397 N/A physical interaction ComPPI
IKBKB TRIM27 25348397 N/A physical interaction ComPPI
IKBKB TP73 25348397 N/A physical interaction ComPPI
IKBKB TRAPPC9 25348397 N/A physical interaction ComPPI
IKBKB PPP2CA 16126728 16129692 24234451 25348397 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
IKBKB CDKN2A 25348397 N/A physical interaction ComPPI
IKBKB TRAF1 25348397 N/A physical interaction ComPPI
IKBKB CSF2RB 25348397 N/A physical interaction ComPPI
IKBKB TSC1 17693255 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,protein kinase assay ComPPI,IntAct
IKBKB NAA20 19716809 25348397 27898060 N/A physical interaction ComPPI,OmniPath
IKBKB BCL2 25348397 N/A physical interaction ComPPI
IKBKB DPP4 25348397 N/A physical interaction ComPPI
IKBKB TAB1 25348397 N/A physical interaction ComPPI
IKBKB HSPB1 25348397 N/A physical interaction ComPPI
IKBKB PYCARD 12486103 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
IKBKB NLRC5 20434986 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB TAB2 25348397 N/A physical interaction ComPPI
IKBKB AURKA 17939994 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,protein kinase assay ComPPI,IntAct
IKBKB TPX2 17939994 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB NGFR 25348397 N/A physical interaction ComPPI
IKBKB SASH1 25348397 N/A physical interaction ComPPI
IKBKB TFAP2C 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IKBKB MTOR 25348397 N/A physical interaction ComPPI
IKBKB RPTOR 25348397 N/A physical interaction ComPPI
IKBKB RICTOR 25348397 N/A physical interaction ComPPI
IKBKB PPARG 25348397 N/A physical interaction ComPPI
IKBKB SHARPIN 21455180 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB DHCR24 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB SLC25A13 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB SLC25A22 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB CD40 25348397 N/A physical interaction ComPPI
IKBKB MAVS 16177806 21782231 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,cosedimentation through density gradient,physical interaction ComPPI,IntAct
IKBKB BIRC3 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
IKBKB CLTC 14743216 24234451 25241761 25348397 physical association physical interaction,tandem affinity purification,proximity ligation assay ComPPI,IntAct
IKBKB STK26 25348397 N/A physical interaction ComPPI
IKBKB COMMD7 25348397 N/A physical interaction ComPPI
IKBKB MACROD1 25348397 N/A physical interaction ComPPI
IKBKB LATS2 25348397 N/A physical interaction ComPPI
IKBKB ITCH 25348397 N/A physical interaction ComPPI
IKBKB USP18 25348397 N/A physical interaction ComPPI
IKBKB KLHL21 25348397 N/A physical interaction ComPPI
IKBKB PSG1 25348397 N/A physical interaction ComPPI
IKBKB MALT1 19118383 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB EPAS1 25348397 N/A physical interaction ComPPI
IKBKB TNIK 22904686 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB IFIT5 25348397 N/A physical interaction ComPPI
IKBKB CSNK1A1 19118383 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKB HSPA1L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB EPRS1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB C1QBP 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB LYZ 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB TIMM50 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IKBKB CCAR2 14525934 14743216 24234451 25348397 physical association experimental interaction detection,tandem affinity purification ComPPI,HPRD,IntAct
IKBKB MARK3 17363905 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKB MYD88 16365431 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IKBKB STAT3 19345327 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKB SQSTM1 19959994 24234451 25348397 colocalization fluorescence technology ComPPI,IntAct
IKBKB RPS3 21399639 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,protein kinase assay ComPPI,IntAct
IKBKB VDAC1 21782231 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
IKBKB MAP3K21 24234451 25348397 26859459 physical association anti tag coimmunoprecipitation ComPPI,IntAct
NFKBIA IKBKB 12486103 14525934 14743216 16126728 16286467 16291755 16319058 16365431 19196987 19345327 21399639 21423167 21765415 22037600 24234451 25348397 25759022 9520446 9721103 phosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,phosphorylation reaction,physical interaction,protein kinase assay,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
IQGAP1 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PKM IKBKB 25348397 N/A protein kinase assay ComPPI
NEDD4L IKBKB 25348397 N/A physical interaction ComPPI
PRKCI IKBKB 25348397 N/A physical interaction ComPPI
HSPA9 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K14 IKBKB 10195894 10733566 14525934 14743216 24234451 25348397 9346485 9520446 phosphorylation reaction,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,protein kinase assay,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CFLAR IKBKB 11002417 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BCL10 IKBKB 17213322 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PELI1 IKBKB 25348397 N/A physical interaction ComPPI
UBB IKBKB 14525934 16267042 N/A experimental interaction detection HPRD
IKBKB TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD
IKBKB IKBKB 10195894 14525934 14743216 16319058 21423167 23776406 24234451 phosphorylation reaction,physical association anti tag coimmunoprecipitation,cosedimentation in solution,experimental interaction detection,light scattering,molecular sieving,x-ray crystallography,protein kinase assay,tandem affinity purification HPRD,IntAct
CALM2 IKBKB 14743216 24234451 physical association tandem affinity purification IntAct
SNAP23 IKBKB 18692471 27898060 N/A N/A OmniPath
SRC IKBKB 10195894 10779355 12645577 12707358 15749833 27898060 stimulant N/A OmniPath
PRKAA2 IKBKB 21673972 27898060 stimulant N/A OmniPath
IKBKB CYLD 15870263 24614225 27898060 inhibition,stimulant N/A OmniPath
PRKCA IKBKB 10022904 10195894 11325957 14514672 16267042 18266467 18930133 20068038 20448038 23123196 24290981 24833394 25486864 27898060 stimulant N/A OmniPath
IKBKB FKBP4 21903422 27898060 N/A N/A OmniPath
IKBKB CTNNB1 11527961 25241761 27898060 N/A N/A OmniPath
CTNNB1 IKBKB 11527961 25241761 27898060 N/A N/A OmniPath
LYN IKBKB 12645577 12707358 20450893 24386391 26353931 27898060 N/A N/A OmniPath
IKBKB TRIM27 16393995 27898060 N/A N/A OmniPath
TRIM27 IKBKB 16393995 27898060 N/A N/A OmniPath
ARRB2 IKBKB 15173580 27898060 N/A N/A OmniPath
IKBKB FKBP5 21903422 27898060 N/A N/A OmniPath
ARRB1 IKBKB 15173580 27898060 N/A N/A OmniPath
MAP3K7 IKBKB 10022904 10094049 10187861 10195894 10779355 10807933 10837071 11129660 11460167 12547194 14530355 15214841 15327770 15502405 15620648 15691841 15836773 16006187 16186825 16260493 16493424 17363905 17363973 17965022 18316610 18456659 19632174 20932476 21331078 24270572 25946971 27898060 9689078 stimulant N/A OmniPath
PLK1 IKBKB 18957422 19202066 27898060 inhibition N/A OmniPath
IKBKB TNFAIP3 11594795 17709380 21220427 27898060 N/A N/A OmniPath
TNFAIP3 IKBKB 11594795 16684768 17709380 21220427 27898060 inhibition N/A OmniPath
IKBKB CSF2RA 12637324 17952117 25241761 27898060 N/A N/A OmniPath
NOD2 IKBKB 10094049 10195894 10837071 15327770 15620648 15691841 16186825 16260493 16493424 17965022 27898060 N/A N/A OmniPath
IKBKB CHUK 10094049 10195894 10733566 10837071 10968790 11057907 11080499 11585904 11864612 11971985 12070292 12210728 12244103 12351658 12486103 14743216 15214841 15218526 15327770 15456791 15620648 15691841 16129692 16186825 16260493 16285893 16286467 16319058 16493424 16970925 17072322 17561400 17693255 17965022 18949366 20932476 21575199 21784860 21903422 24240172 25241761 25748427 25852190 27898060 9346241 9346484 9346485 9721103 9751060 9891086 9914500 stimulant N/A OmniPath
CHUK IKBKB 10022904 10094049 10195894 10733566 10779355 10837071 10968790 11057907 11080499 11585904 11864612 11971985 12070292 12210728 12244103 12351658 12486103 14743216 15214841 15218526 15327770 15456791 15620648 15691841 16129692 16186825 16260493 16285893 16286467 16319058 16493424 16970925 17072322 17561400 17693255 17965022 18949366 20932476 21575199 21784860 21903422 24240172 25241761 25748427 25852190 27898060 9346241 9346484 9346485 9689078 9721103 9751060 9891086 9914500 N/A N/A OmniPath
TRAF2 IKBKB 10795740 11359906 15725726 18362886 19150425 20449947 23007157 25241761 27898060 stimulant N/A OmniPath
IKBKB TICAM1 14739303 27898060 N/A N/A OmniPath
ABL2 IKBKB 21552281 27898060 N/A N/A OmniPath
RIPK2 IKBKB 10094049 10195894 10329646 10837071 10880512 11087742 11463746 15327770 15620648 15691841 16186825 16260493 16493424 17947236 17965022 27898060 stimulant N/A OmniPath
IKBKB EIF2AK2 10848580 16600570 27898060 stimulant N/A OmniPath
IKBKB HSPD1 16840786 27898060 N/A N/A OmniPath
PYCARD IKBKB 12486103 27898060 N/A N/A OmniPath
IKBKB IKBKE 21138416 23453969 27898060 9914500 N/A N/A OmniPath
IKBKE IKBKB 21138416 23453969 27898060 9914500 N/A N/A OmniPath
IKBKB MAP3K14 10195894 10713178 10733566 11278268 14743216 16286467 27898060 9346485 9520446 N/A N/A OmniPath
MAP3K14 IKBKB 10072079 10195894 10713178 10733566 11278268 14743216 16285893 16286467 27898060 9346485 9520446 stimulant N/A OmniPath
IKBKB BCL10 11113112 14695475 16818229 17213322 21199863 27898060 N/A N/A OmniPath
IKBKB FOXO3 15084260 19188143 22531926 23691078 25241761 27898060 inhibition N/A OmniPath
FOXO3 IKBKB 15084260 22531926 25241761 27898060 N/A N/A OmniPath
CASP3 IKBKB 11741536 27898060 9367996 inhibition N/A OmniPath
IKBKB MAP3K1 11057907 16286467 27898060 9819420 N/A N/A OmniPath
MAP3K1 IKBKB 11057907 16285893 16286467 27898060 9008162 9520401 9689078 9819420 stimulant N/A OmniPath
IKBKB NCOA3 11971985 15302935 15383283 16051665 16135815 16964243 18669648 19413330 19651622 20068231 27898060 stimulant N/A OmniPath
NCOA3 IKBKB 11971985 15383283 16051665 16135815 27898060 N/A N/A OmniPath
TRAF6 IKBKB 10094049 10195894 10837071 15327770 15620648 15691841 16186825 16260493 16493424 17965022 27898060 stimulant N/A OmniPath
IKBKB NCOR2 21903422 27898060 N/A N/A OmniPath
IKBKB PPP1R15A 18362886 27898060 N/A N/A OmniPath
IKBKB NFKB1 10469655 10835356 11158290 11297557 11976329 12482991 15199157 19250910 25241761 27898060 inhibition,stimulant N/A OmniPath
NFKB1 IKBKB 10469655 10835356 11158290 11976329 25241761 27898060 stimulant N/A OmniPath
MAVS IKBKB 16153868 16177806 17468758 18207245 21903422 27898060 stimulant N/A OmniPath
IKBKB BAD 23332762 27898060 inhibition N/A OmniPath
MLST8 IKBKB 18755269 27898060 N/A N/A OmniPath
IKBKB ATM 16497931 27898060 N/A N/A OmniPath
IKBKB PEBP1 11585904 27898060 N/A N/A OmniPath
IKBKB TP63 23589370 27898060 stimulant N/A OmniPath
IKBKB IRS1 10722755 11606564 12351658 12555073 15613682 17229808 18077418 18160431 19651622 21040800 27898060 inhibition N/A OmniPath
PPM1A IKBKB 18930133 27898060 inhibition N/A OmniPath
IKBKB REL 16888014 27898060 N/A N/A OmniPath
IKBKB IKBKG 10094049 10195894 10748240 10837071 10968790 10980203 11057907 11583588 11864612 11865184 11971985 12133833 12192055 12459277 12486103 12612076 12657630 12808104 14743216 15184390 15214841 15218526 15327770 15620648 15691841 15749833 15802604 15836773 16126728 16129692 16186825 16260493 16285893 16319058 16378096 16493424 16497931 16547522 16583354 16603398 16611882 16906147 16938294 16970925 17000764 17072322 17363973 17561400 17568778 17693255 17965022 17977820 18037881 18207244 18266324 18266467 18450452 18462684 18583959 18691976 18949366 19365808 19422324 19656241 19666608 19706536 19815509 19820708 19959994 20098747 20167598 20300203 20368414 20932476 21423167 21455180 21606193 21803029 21811235 21903422 22099304 22605335 22990857 23131831 23506214 23825957 23871670 23986494 24240172 24266532 24369075 24469399 24618592 25286246 25304104 25400026 25852190 25979343 26496610 27898060 9751060 inhibition,stimulant N/A OmniPath
IKBKG IKBKB 10094049 10195894 10748240 10837071 10968790 10980203 11057907 11583588 11864612 11865184 11971985 12133833 12192055 12459277 12486103 12612076 12657630 12808104 14743216 15184390 15214841 15218526 15327770 15620648 15691841 15749833 15802604 15836773 16126728 16129692 16186825 16260493 16285893 16319058 16378096 16493424 16497931 16547522 16583354 16603398 16611882 16906147 16938294 16970925 17000764 17072322 17363973 17561400 17568778 17693255 17965022 17977820 18037881 18207244 18266324 18266467 18329793 18450452 18462684 18583959 18949366 19365808 19422324 19656241 19666608 19706536 19815509 19820708 19959994 20098747 20167598 20300203 20368414 20932476 21423167 21455180 21606193 21803029 21903422 22099304 22605335 22990857 23131831 23506214 23825957 23871670 23986494 24240172 24266532 24369075 24469399 24618592 25286246 25304104 25400026 25852190 25979343 26496610 27898060 9751060 stimulant N/A OmniPath
IKBKB FOS 19285436 27898060 N/A N/A OmniPath
PRKCQ IKBKB 11120819 15802604 17363905 20164171 27898060 stimulant N/A OmniPath
GLRX IKBKB 16916935 27898060 stimulant N/A OmniPath
IKBKB FANCA 12210728 27898060 N/A N/A OmniPath
FANCA IKBKB 12210728 27898060 N/A N/A OmniPath
IKBKB TP53 19883646 27898060 N/A N/A OmniPath
IKBKB IRS2 12351658 27898060 inhibition N/A OmniPath
IKBKB IRF5 18836453 22412986 25326418 27898060 N/A N/A OmniPath
PRKCZ IKBKB 10022904 10195894 10356400 10779355 27898060 9689078 stimulant N/A OmniPath
IKBKB IRF3 17526488 18272581 25070846 27898060 9566918 stimulant N/A OmniPath
IKBKB CASP8 11002417 27898060 N/A N/A OmniPath
IKBKB NFKBIA 10085062 10195894 10320352 10329646 10398585 10527519 10602462 10722693 10723127 10723801 10754328 10764587 10807933 10823818 10880512 10882136 10889159 11057907 11080499 11087742 11158290 11266466 11297557 11350057 11368781 11502888 11527961 11706022 11752211 11753679 11960379 12054687 12060665 12085227 12138192 12411322 12429743 12432072 12444159 12486103 12514169 12527907 12709429 12943667 12949498 14523047 14743216 15024091 15125833 15125834 15145317 15214841 15218148 15218526 15371334 15470067 15574499 15695387 15836773 15856023 16007147 16023083 16153868 16177806 16207329 16285893 16286467 16291755 16319058 16365431 16493424 16495515 16611882 16619039 16737960 16793322 16818647 16846590 16888014 16920985 16965765 16970925 17072322 17079871 17363905 17468758 17533369 17561400 17706453 17965022 18519641 18981174 19196987 19959994 20434986 20449947 20696840 20797629 21232017 21399639 21423167 21765415 21862579 22022389 22037600 22990857 23816567 24469399 24611898 24618592 24912152 25595906 25759022 26195767 26740240 26802121 27898060 7479976 7739562 7796813 7862124 7878466 8550590 8601309 8649784 8657102 9214631 9252186 9346484 9346485 9520446 9689078 9707608 9721103 9734360 9751059 9891086 9914500 inhibition,stimulant N/A OmniPath
NFKBIA IKBKB 10085062 10320352 10527519 10807933 10889159 11080499 11158290 11368781 11527961 12054687 12411322 12429743 12486103 12709429 12943667 14743216 15024091 15125833 15125834 15218148 15574499 15856023 16023083 16286467 16291755 16319058 16365431 16611882 16737960 16818647 16888014 17079871 17363905 18519641 18981174 19196987 19959994 20434986 20449947 20797629 21232017 21399639 21423167 21765415 21862579 22022389 22037600 22990857 23816567 24469399 24611898 24618592 24912152 25595906 25759022 26740240 26802121 27898060 9346485 9520446 9689078 9721103 9751059 9891086 9914500 N/A N/A OmniPath
IKBKB CDKN2A 12529334 20152798 27898060 inhibition N/A OmniPath
LTBR IKBKB 15743811 27898060 N/A N/A OmniPath
CRKL IKBKB 24145029 27898060 N/A N/A OmniPath
IKBKB NFE2L2 18241676 27898060 inhibition N/A OmniPath
PPP1CA IKBKB 18362886 18949366 27898060 N/A N/A OmniPath
IKBKB BIRC3 15494311 25241761 27898060 N/A N/A OmniPath
IKBKB RELA 10521409 12842894 15128824 15280197 15465828 15489227 16046471 16407239 18519641 25241761 27898060 stimulant N/A OmniPath
IKBKB SGK1 15695387 27898060 N/A N/A OmniPath
IKBKB NOTCH1 18560356 27898060 N/A N/A OmniPath
PPP2CA IKBKB 16126728 16129692 19607706 27898060 N/A N/A OmniPath
IKBKB FLT3 18670883 27898060 N/A N/A OmniPath
KEAP1 IKBKB 19818716 20600852 24127568 24322982 25926686 27898060 inhibition N/A OmniPath
RIPK1 IKBKB 10980203 18362886 21606198 27898060 stimulant N/A OmniPath
IKBKB TNFRSF1A 10755617 11002417 11821416 18949366 21331078 21724995 23815148 25241761 27898060 N/A N/A OmniPath
UBE2N IKBKB 10094049 10195894 10837071 15327770 15620648 15691841 16186825 16260493 17965022 27898060 N/A N/A OmniPath
IKBKB TBK1 10022904 10195894 10783893 11839743 14560022 16207722 19369195 21138416 21903422 27898060 N/A N/A OmniPath
TBK1 IKBKB 10022904 10195894 10783893 11839743 14560022 14743216 16207722 19369195 21138416 21903422 27898060 stimulant N/A OmniPath
IKBKB SQSTM1 10356400 27898060 stimulant N/A OmniPath
IKBKB NFKBIB 10320352 10593965 10723801 11470788 14743216 15145317 15218526 15836773 16260493 17072322 27898060 8657102 9346241 9346485 9689078 9721103 inhibition,stimulant N/A OmniPath
NFKBIB IKBKB 10320352 10593965 11470788 14743216 16260493 27898060 9346485 9689078 9721103 N/A N/A OmniPath
MTOR IKBKB 18490760 18519641 27898060 N/A N/A OmniPath
IKBKB HSPB1 16840786 27898060 N/A N/A OmniPath
HSPB1 IKBKB 16840786 27898060 N/A N/A OmniPath
MAP3K3 IKBKB 11429546 14743216 15214841 15371334 15572679 16737960 17197697 27898060 stimulant N/A OmniPath
IRAK1 IKBKB 11096118 18180283 27898060 stimulant N/A OmniPath
IKBKB RELB 25267645 27898060 N/A N/A OmniPath
IKBKB TSC1 17693255 18075516 19188143 24135021 27898060 inhibition N/A OmniPath
TSC1 IKBKB 17693255 27898060 N/A N/A OmniPath
NFKBIE IKBKB 10320352 27898060 N/A N/A OmniPath
IKBKB NFKBIE 10320352 15218526 27898060 stimulant N/A OmniPath
IKBKB TANK 12133833 27898060 N/A N/A OmniPath
ELP1 IKBKB 27898060 9751059 N/A N/A OmniPath
IKBKB TRPC4AP 14585990 27898060 N/A N/A OmniPath
TRPC4AP IKBKB 14585990 27898060 N/A N/A OmniPath
IKBKB NLRX1 21703539 27898060 N/A N/A OmniPath
IKBKB IKBIP 17952117 27898060 N/A N/A OmniPath
NOD1 IKBKB 10195894 10837071 15691841 27898060 N/A N/A OmniPath
IKBKB PPM1B 14585847 27898060 N/A N/A OmniPath
PPM1B IKBKB 14585847 18930133 27898060 inhibition N/A OmniPath
IKBKB STAP2 16365431 27898060 N/A N/A OmniPath
STAP2 IKBKB 16365431 27898060 N/A N/A OmniPath
IKBKB PRDX3 12492477 27898060 N/A N/A OmniPath
CUEDC2 IKBKB 18362886 27898060 N/A N/A OmniPath
IKBKB YWHAB 16024783 27898060 inhibition N/A OmniPath
YWHAB IKBKB 16024783 27898060 N/A N/A OmniPath
IKBKB MAP3K13 12492477 27898060 N/A N/A OmniPath
IKBKB SASH1 23776175 27898060 N/A N/A OmniPath
DNAJA3 IKBKB 15601829 27898060 inhibition N/A OmniPath
PYDC1 IKBKB 12656673 27898060 N/A N/A OmniPath
IKBKB MAP3K11 10713178 27898060 N/A N/A OmniPath
IKBKB DOK1 15574499 27898060 stimulant N/A OmniPath
IKBKB BBC3 21364664 21997190 27898060 N/A N/A OmniPath
IKBKB NLRP2 15456791 27898060 N/A N/A OmniPath
NLRP2 IKBKB 15456791 27898060 N/A N/A OmniPath
IKBKB CTNNAL1 17952117 27898060 N/A N/A OmniPath
IKBKB RPS3 21399639 27898060 N/A N/A OmniPath
IKBKB CDC37 11864612 14743216 16970925 17072322 21903422 25036637 26496610 27898060 N/A N/A OmniPath
PPP2CB IKBKB 17188031 19607706 27898060 inhibition N/A OmniPath
PPM1M IKBKB 19594441 27898060 N/A N/A OmniPath

Visualization










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