Gene Information gene info

  1. Home

GENE：ABI1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ABI1
FullNmae abl interactor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11320
EnsembleID ENSG00000136754
Uniprot Q8IZP0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ABI1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ABI1 GO:0001756,GO:0005515,GO:0005622,GO:0005634,GO:0005783,GO:0005829,GO:0005856,GO:0007169,GO:0008092,GO:0008154,GO:0008285,GO:0014069,GO:0017124,GO:0017124,GO:0030027,GO:0030027,GO:0030296,GO:0030426,GO:0031209,GO:0032433,GO:0035591,GO:0035591,GO:0035855,GO:0045296,GO:0048813,GO:0061098,GO:0070062,GO:0072673

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ABI1 hsa:10006 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
ABI1 hsa:10006 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ABI1 ABL1 23331499 9010225 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ABI1 ABL1 20005715 interaction type N/A PSP
ABI1 CBL 17395426 20005715 20542890 interaction type,stimulation N/A PSP,SignaLink
ABI1 PRKAA1 20005715 interaction type N/A PSP,SignaLink
ABI1 PAK2 20005715 interaction type N/A PSP
ABI1 ABL1 20005715 N/A N/A SignaLink
ABI1 PAK2 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 ABI1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ABI1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ABI1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ABI1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ABI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
MAPK3 ABI1 22135298 phosphorylation N/A PhosphoSite
CDK1 ABI1 22135298 phosphorylation N/A PhosphoSite
ABL1 ABI1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPK1 ABI1 22135298 phosphorylation N/A PhosphoSite
NCK1 ABI1 25361965 interaction type N/A PTMCode2
ABI1 NCK1 25361965 interaction type N/A PTMCode2
EPS8 ABI1 25361965 interaction type N/A PTMCode2
ABI1 EPS8 25361965 interaction type N/A PTMCode2
ENAH ABI1 25361965 interaction type N/A PTMCode2
ABI1 ENAH 25361965 interaction type N/A PTMCode2
ABI1 WAS 25361965 interaction type N/A PTMCode2
WAS ABI1 25361965 interaction type N/A PTMCode2
ABI1 MYC 25361965 interaction type N/A PTMCode2
MYC ABI1 25361965 interaction type N/A PTMCode2
ABI1 SOS1 25361965 interaction type N/A PTMCode2
SOS1 ABI1 25361965 interaction type N/A PTMCode2
ABI1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 ABI1 25361965 interaction type N/A PTMCode2
ABI1 WASF2 25361965 interaction type N/A PTMCode2
WASF2 ABI1 25361965 interaction type N/A PTMCode2
EPS8L3 ABI1 25361965 interaction type N/A PTMCode2
ABI1 EPS8L3 25361965 interaction type N/A PTMCode2
EPS8L1 ABI1 25361965 interaction type N/A PTMCode2
ABI1 EPS8L1 25361965 interaction type N/A PTMCode2
NCKAP1 ABI1 25361965 interaction type N/A PTMCode2
ABI1 NCKAP1 25361965 interaction type N/A PTMCode2
EPS8L2 ABI1 25361965 interaction type N/A PTMCode2
ABI1 EPS8L2 25361965 interaction type N/A PTMCode2
SOS2 ABI1 25361965 interaction type N/A PTMCode2
ABI1 SOS2 25361965 interaction type N/A PTMCode2
HCK ABI1 25361965 interaction type N/A PTMCode2
ABI1 HCK 25361965 interaction type N/A PTMCode2
SRC ABI1 25361965 interaction type N/A PTMCode2
ABI1 SRC 25361965 interaction type N/A PTMCode2
ABI1 ABL1 25361965 interaction type N/A PTMCode2
BAIAP2 ABI1 25361965 interaction type N/A PTMCode2
ABI1 BAIAP2 25361965 interaction type N/A PTMCode2
CRK ABI1 25361965 interaction type N/A PTMCode2
ABI1 CRK 25361965 interaction type N/A PTMCode2
WASF1 ABI1 25361965 interaction type N/A PTMCode2
ABI1 WASF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SF3A3 ABI1 25348397 N/A physical interaction ComPPI
NCK2 ABI1 11557983 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HNRNPK ABI1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PIK3R2 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
YES1 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
WASL ABI1 25348397 N/A physical interaction ComPPI
HSPA8 ABI1 14525934 15048123 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
PAK2 ABI1 11956071 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
VASP ABI1 14525934 16055720 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PPP2R1A ABI1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK6 ABI1 22094256 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
MRFAP1L1 ABI1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
CCDC22 ABI1 25348397 N/A physical interaction ComPPI
KEAP1 ABI1 25348397 N/A physical interaction ComPPI
MRFAP1 ABI1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
CRK ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
LHX4 ABI1 25348397 N/A physical interaction ComPPI
CBL ABI1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
VAV1 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
CBLB ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
VAV2 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
LYN ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
PIK3R1 ABI1 20598684 24234451 25348397 N/A array technology,physical interaction ComPPI,IntAct
SRC ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
GRB10 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
CRKL ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
LCK ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
SOS1 ABI1 10499589 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
NCK1 ABI1 11418237 14525934 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBXN11 ABI1 25348397 N/A physical interaction ComPPI
CBLC ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
EVL ABI1 14525934 16055720 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GRB2 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
ITK ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
INPPL1 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
SORBS1 ABI1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
KTN1 ABI1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
FES ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
PIK3R3 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
PRKAA1 ABI1 20368287 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
SOS2 ABI1 11003655 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SOCS7 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
CDH1 ABI1 25348397 N/A physical interaction ComPPI
PRPF40A ABI1 25348397 N/A physical interaction ComPPI
TLN1 ABI1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
EPS8 ABI1 1049958 10499589 11099046 12127568 14525934 15289329 25348397 9010225 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RBM14 ABI1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WASF1 ABI1 14525934 15048123 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,inference by socio-affinity scoring ComPPI,HPRD,IntAct
ENAH ABI1 12672821 14525934 16055720 17101133 24234451 25348397 26496610 association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
APBB1 ABI1 25348397 N/A physical interaction ComPPI
FER ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
NCF1 ABI1 12681507 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,pull down,in vitro ComPPI,IntAct,OmniPath
SPTAN1 ABI1 14525934 25348397 9593709 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
MKI67 ABI1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FRK ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
HOMER3 ABI1 25348397 N/A physical interaction ComPPI
ABI1 SPTA1 14525934 24234451 25348397 9593709 physical association two hybrid,experimental interaction detection,filter binding,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ABI1 NCKAP1 11418237 14525934 15048123 16055720 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
ABI1 CYFIP2 14525934 15048123 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
ABI1 NIN 14525934 15048123 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
ABI1 EPS8L1 14525934 14565974 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ABI1 MINK1 14525934 15032605 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
ABI1 NEB 14525934 15048123 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
ABI1 EPS8L2 25348397 N/A physical interaction ComPPI
ABI1 EPS8L3 25348397 N/A physical interaction ComPPI
ABI1 ABL1 11418237 12672821 14525934 17101133 18328268 20598684 24234451 25348397 8943360 9010225 9593709 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,array technology,two hybrid,experimental interaction detection,far western blotting,filter binding,fluorescence technology,pull down,surface plasmon resonance,physical interaction,two hybrid ComPPI,HPRD,IntAct
ABI1 RYK 25348397 N/A physical interaction ComPPI
ABI1 CACNA1A 21078624 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
ABI1 CDC123 25348397 N/A physical interaction ComPPI
ABI1 CTTN 25348397 N/A physical interaction ComPPI
ABI1 TCERG1 25348397 N/A physical interaction ComPPI
ABI1 GAS7 16055720 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
ABI1 WASF2 14525934 15048123 16055720 17101133 24234451 25348397 26496610 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique ComPPI,HPRD,IntAct
ABI1 ZNF511 25348397 N/A physical interaction ComPPI
ABI1 ODF3L2 25348397 N/A physical interaction ComPPI
ABI1 DTNBP1 25348397 N/A physical interaction ComPPI
ABI1 PCMT1 25348397 N/A physical interaction ComPPI
ABI1 BAIAP2 15289329 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ABI1 CYFIP1 15048123 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ABI1 NCKAP1L 25348397 N/A physical interaction ComPPI
ABI1 SSB 25348397 N/A physical interaction ComPPI
ABI1 NHS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABI1 ABI2 25348397 N/A physical interaction ComPPI
ABI1 BRK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABI1 NHSL1 25348397 N/A physical interaction ComPPI
ABI1 KIAA1522 25348397 N/A physical interaction ComPPI
ABI1 RAPH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABI1 THOC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABI1 TCF4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ABI1 ZNF746 25348397 N/A physical interaction ComPPI
ABI1 IKBIP 25348397 N/A physical interaction ComPPI
ABI1 AMZ1 25348397 N/A physical interaction ComPPI
ABI1 WASF3 25348397 N/A physical interaction ComPPI
ABI1 TIMM50 25348397 N/A physical interaction ComPPI
ABI1 NHSL2 25348397 N/A physical interaction ComPPI
ABI1 CGB2 25348397 N/A physical interaction ComPPI
ABI1 COG6 25348397 N/A physical interaction ComPPI
ABI1 CDH23 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ABI1 NXN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ABI1 ITGA4 21173240 25348397 27898060 N/A pull down,physical interaction ComPPI,OmniPath
ABI1 FYN 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
ABI1 FGR 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
ABI1 HCK 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
ABI1 RASA1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
ABI1 PLCG1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
ABI1 ABL2 20598684 24234451 25348397 27898060 7590237 N/A array technology ComPPI,IntAct,OmniPath
ABI1 DST 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ABI1 KIAA0408 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ABI1 SYNE2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ABI1 SRP68 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ABI1 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ABI1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SRRM1 ABI1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAAT ABI1 25348397 N/A physical interaction ComPPI
ABI1 ABI1 12672821 14525934 N/A experimental interaction detection HPRD
MAPK3 ABI1 21419341 27898060 stimulant N/A OmniPath
ABL1 ABI1 11418237 12672821 17101133 17389395 18083107 18328268 19534553 20598684 20841568 21320496 27898060 8943360 9010225 9593709 stimulant N/A OmniPath
ABI1 ABL1 11418237 12672821 17101133 18328268 20598684 21320496 27898060 8943360 9010225 9593709 stimulant N/A OmniPath
ABI1 CBL 17395426 27898060 stimulant N/A OmniPath
MAPK1 ABI1 17855441 18088087 21419341 21900237 27898060 stimulant N/A OmniPath

Visualization










  Return