Gene Information gene info

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GENE：AKAP12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AKAP12
FullNmae A-kinase anchoring protein 12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:370
EnsembleID ENSG00000131016
Uniprot Q02952

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AKAP12 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AKAP12 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AKAP12 GO:0005515,GO:0005516,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0005925,GO:0005938,GO:0007165,GO:0007186,GO:0007193,GO:0008179,GO:0010738,GO:0010738,GO:0010739,GO:0032496,GO:0032760,GO:0035733,GO:0043025,GO:0043116,GO:0050804,GO:0051018,GO:0051602,GO:0051770,GO:0061870,GO:0070374,GO:0071347,GO:0071356,GO:0090036,GO:0098685,GO:1900143

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AKAP12 ADRB2 20005715 interaction type N/A PSP
AKAP12 PRKCA 20005715 interaction type N/A PSP
AKAP12 GRK2 20005715 interaction type N/A PSP
AKAP12 PDE4D 20005715 interaction type N/A PSP
AKAP12 GRK2 11309381 18988627 20005715 20005715 N/A N/A SignaLink
AKAP12 PRKCA 11316952 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR AKAP12 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 AKAP12 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 AKAP12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AKAP12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AKAP12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AKAP12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AKAP12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AKAP12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HDAC7 AKAP12 22584896 trascriptional regulation,stimulation inferred by curator TFlink
HDAC9 AKAP12 22584896 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 AKAP12 22584896 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000345DEB AKAP12 20979053 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS000021D7C8 AKAP12 20979053 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000345DEB AKAP12 20979053 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000021D7C8 AKAP12 20979053 23622248 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,clash,miRNA interference luciferase reporter assay TarBase
URS0000070B1D AKAP12 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000512C88 AKAP12 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 AKAP12 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B2B AKAP12 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003E2232 AKAP12 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED AKAP12 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004F507C AKAP12 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000072B4C8 AKAP12 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 AKAP12 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 AKAP12 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD AKAP12 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 AKAP12 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA AKAP12 22135298 phosphorylation N/A PhosphoSite
CDK1 AKAP12 22135298 phosphorylation N/A PhosphoSite
ATR AKAP12 22135298 phosphorylation N/A PhosphoSite
AKAP12 PRKCA 25361965 interaction type N/A PTMCode2
PRKCA AKAP12 25361965 interaction type N/A PTMCode2
AKAP12 ADRB2 25361965 interaction type N/A PTMCode2
ADRB2 AKAP12 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SGTB AKAP12 25348397 N/A physical interaction ComPPI
NECTIN2 AKAP12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRKCA AKAP12 11316952 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FLNA AKAP12 25348397 N/A physical interaction ComPPI
DYNC1LI1 AKAP12 25348397 N/A physical interaction ComPPI
PRKAR2A AKAP12 11316952 14525934 16642035 24234451 25348397 physical association experimental interaction detection,filter binding,physical interaction,in vitro ComPPI,HPRD,IntAct
AKAP12 GRK2 11309381 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
AKAP12 ADRB2 11309381 14525934 25348397 27898060 9880537 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
AKAP12 EGFR 20029029 24234451 25348397 physical association anti tag coimmunoprecipitation,ubiquitin reconstruction,physical interaction ComPPI,IntAct
AKAP12 FHL1 21900206 23414517 24234451 25348397 physical association two hybrid,physical interaction,two hybrid fragment pooling approach ComPPI,IntAct
AKAP12 DYNC1H1 25348397 N/A physical interaction ComPPI
AKAP12 DYNC1I2 25348397 N/A physical interaction ComPPI
AKAP12 DYNLRB1 25348397 N/A physical interaction ComPPI
AKAP12 SPRTN 25348397 N/A physical interaction ComPPI
AKAP12 CEP250 25348397 N/A physical interaction ComPPI
AKAP12 TP53 25348397 N/A physical interaction ComPPI
AKAP12 TUBGCP3 25348397 N/A physical interaction ComPPI
AKAP12 EID3 25348397 N/A physical interaction ComPPI
AKAP12 PTEN 25348397 N/A physical interaction ComPPI
AKAP12 CEP290 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP12 OFD1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP12 SCLT1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP12 RAB2A 25348397 N/A physical interaction ComPPI
AKAP12 SIN3B 25348397 N/A physical interaction ComPPI
AKAP12 SAMHD1 25348397 N/A physical interaction ComPPI
AKAP12 PDE4D 16642035 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP12 STK4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AKAP12 KIF3C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AKAP12 DYRK2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AKAP12 KIF3B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AKAP12 SAV1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AKAP12 BRCA1 25348397 N/A physical interaction ComPPI
AKAP12 CFTR 25348397 N/A physical interaction ComPPI
AKAP12 CTNNB1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
AKAP12 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
AKAP12 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AKAP12 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AKAP12 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AKAP12 SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AKAP12 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AKAP12 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PRKACA AKAP12 14657015 18510355 27898060 N/A N/A OmniPath
CDK1 AKAP12 23063527 27898060 N/A N/A OmniPath

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