Gene Information gene info

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GENE：ARHGDIB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARHGDIB
FullNmae Rho GDP dissociation inhibitor beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:679
EnsembleID ENSG00000111348
Uniprot P52566

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARHGDIB necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARHGDIB mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARHGDIB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARHGDIB apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARHGDIB GO:0003924,GO:0005094,GO:0005094,GO:0005096,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0005856,GO:0007266,GO:0016020,GO:0031267,GO:0031410,GO:0035023,GO:0035023,GO:0070062,GO:0071461,GO:1901164

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARHGDIB hsa:397 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
ARHGDIB hsa:397 path:hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CARD9 ARHGDIB 22423967 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ARHGDIB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ARHGDIB 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ARHGDIB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ARHGDIB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARHGDIB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARHGDIB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ARHGDIB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 ARHGDIB 23349340 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SYK ARHGDIB 22135298 phosphorylation N/A PhosphoSite
SRC ARHGDIB 22135298 phosphorylation N/A PhosphoSite
PRKCA ARHGDIB 22135298 phosphorylation N/A PhosphoSite
ARHGDIB RAC2 25361965 interaction type N/A PTMCode2
RAC2 ARHGDIB 25361965 interaction type N/A PTMCode2
ARHGDIB CASP3 25361965 interaction type N/A PTMCode2
CASP3 ARHGDIB 25361965 interaction type N/A PTMCode2
ARHGDIB CDC42 25361965 interaction type N/A PTMCode2
CDC42 ARHGDIB 25361965 interaction type N/A PTMCode2
ARHGDIB EZR 25361965 interaction type N/A PTMCode2
EZR ARHGDIB 25361965 interaction type N/A PTMCode2
ARHGDIB RAC1 25361965 interaction type N/A PTMCode2
RAC1 ARHGDIB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC42 ARHGDIB 14525934 25348397 9799233 N/A experimental interaction detection,in vivo ComPPI,HPRD
RAC1 ARHGDIB 14525934 21900206 24234451 25348397 9799233 physical association two hybrid,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
VAV1 ARHGDIB 10664460 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ARHGDIB CASP3 14525934 18723680 24234451 25348397 8626669 cleavage reaction experimental interaction detection,cleavage reaction,protease assay,in vitro ComPPI,HPRD,IntAct
ARHGDIB RHOH 11368848 11809807 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ARHGDIB RAC2 10655614 14525934 24234451 25348397 27898060 N/A experimental interaction detection,x-ray crystallography,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
ARHGDIB EZR 14525934 25348397 9287351 N/A experimental interaction detection,in vitro ComPPI,HPRD
ARHGDIB RAC3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ARHGDIB UFM1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ARHGDIB APP 25348397 N/A physical interaction ComPPI
ARHGDIB ZBTB1 25348397 N/A physical interaction ComPPI
ARHGDIB SUMO4 25348397 N/A physical interaction ComPPI
ARHGDIB WSB1 25348397 N/A physical interaction ComPPI
ARHGDIB UBE3A 25348397 N/A physical interaction ComPPI
ARHGDIB U2AF2 25348397 N/A physical interaction ComPPI
ARHGDIB FBXL5 25348397 N/A physical interaction ComPPI
ARHGDIB CDH1 25348397 N/A physical interaction ComPPI
ARHGDIB CASP7 18723680 24234451 25348397 cleavage reaction cleavage reaction,protease assay ComPPI,IntAct
ARHGDIB ANKRD1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
RHOC ARHGDIB 25348397 N/A physical interaction ComPPI
RHOA ARHGDIB 14525934 25348397 9799233 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PRKCA ARHGDIB 22469974 27898060 inhibition N/A OmniPath
SYK ARHGDIB 19321744 24055812 27898060 N/A N/A OmniPath

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