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GENE：RNASEH2B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNASEH2B
FullNmae ribonuclease H2 subunit B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25671
EnsembleID ENSG00000136104
Uniprot Q5TBB1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNASEH2B parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNASEH2B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RNASEH2B GO:0001701,GO:0005654,GO:0005654,GO:0006298,GO:0006401,GO:0006401,GO:0009259,GO:0010389,GO:0010467,GO:0010629,GO:0032299,GO:0032299,GO:0032299,GO:0048144,GO:0048146,GO:2000001

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RNASEH2B hsa:79621 path:hsa03030 DNA replication - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 RNASEH2B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RNASEH2B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 RNASEH2B 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RNASEH2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RNASEH2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RNASEH2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RNASEH2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RNASEH2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RNASEH2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RNASEH2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005FDE70 RNASEH2B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000137EDE RNASEH2B 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A RNASEH2B 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B RNASEH2B 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC RNASEH2B 23592263 23824327 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 RNASEH2B 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 RNASEH2B 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 RNASEH2B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 RNASEH2B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 RNASEH2B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B RNASEH2B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F RNASEH2B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 RNASEH2B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F RNASEH2B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D RNASEH2B 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
JUNB RNASEH2B 25361965 interaction type N/A PTMCode2
RNASEH2B JUNB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SAP18 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2BC4 RNASEH2B 25348397 N/A physical interaction ComPPI
VBP1 RNASEH2B 25348397 N/A physical interaction ComPPI
WT1 RNASEH2B 25348397 N/A physical interaction ComPPI
AP1M1 RNASEH2B 25348397 N/A physical interaction ComPPI
RDX RNASEH2B 25348397 N/A physical interaction ComPPI
YWHAQ RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRM1 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBQLN2 RNASEH2B 25348397 N/A physical interaction ComPPI
H3C1 RNASEH2B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BCOR RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIVEP1 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB1 RNASEH2B 25348397 N/A physical interaction ComPPI
STAMBP RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DAB2IP RNASEH2B 25348397 N/A physical interaction ComPPI
PSMD5 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRINP1 RNASEH2B 25348397 N/A physical interaction ComPPI
ARPC5 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KCTD3 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FERMT1 RNASEH2B 25348397 N/A physical interaction ComPPI
ABCA2 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NRAS RNASEH2B 25348397 N/A physical interaction ComPPI
KLHDC2 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SYNE2 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNRC6B RNASEH2B 25348397 N/A physical interaction ComPPI
H2BC11 RNASEH2B 25348397 N/A physical interaction ComPPI
MKNK1 RNASEH2B 25348397 N/A physical interaction ComPPI
ANP32E RNASEH2B 25348397 N/A physical interaction ComPPI
RABGAP1L RNASEH2B 25348397 N/A physical interaction ComPPI
RABGAP1L RNASEH2B 25348397 N/A physical interaction ComPPI
FOXM1 RNASEH2B 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CEP164 RNASEH2B 25348397 N/A physical interaction ComPPI
RNF213 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLPTM1 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HERPUD2 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC39A10 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC2 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNASEH2A RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNASEH2C RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNASEH2B DMAC2L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNASEH2B PDF 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNASEH2B ZMYM1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNASEH2B C1ORF52 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00008C3BD5 RNASEH2B 27087310 direct interaction,inhibition N/A NPInter

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