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GENE：AXIN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AXIN1
FullNmae axin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:903
EnsembleID ENSG00000103126
Uniprot O15169

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AXIN1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AXIN1 GO:0001701,GO:0001934,GO:0002039,GO:0005515,GO:0005634,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0005886,GO:0005938,GO:0006913,GO:0006915,GO:0007605,GO:0008013,GO:0008013,GO:0009950,GO:0010629,GO:0010800,GO:0015630,GO:0016328,GO:0019899,GO:0019901,GO:0019901,GO:0030511,GO:0030877,GO:0030877,GO:0030877,GO:0031122,GO:0031398,GO:0031398,GO:0031410,GO:0031625,GO:0031625,GO:0032147,GO:0032436,GO:0033138,GO:0034244,GO:0035591,GO:0036342,GO:0042802,GO:0042802,GO:0042802,GO:0042803,GO:0043161,GO:0043621,GO:0045599,GO:0045732,GO:0045732,GO:0045860,GO:0046330,GO:0046332,GO:0048320,GO:0048468,GO:0048471,GO:0051248,GO:0060070,GO:0060090,GO:0060090,GO:0060322,GO:0065003,GO:0070016,GO:0070411,GO:0070411,GO:0070412,GO:0071514,GO:0071944,GO:0090090,GO:0090090,GO:0090090,GO:0090090,GO:1990756,GO:1990909,GO:2000060

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AXIN1 hsa:8312 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa04934 Cushing syndrome - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05010 Alzheimer disease - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05200 Pathways in cancer - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05210 Colorectal cancer - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05213 Endometrial cancer - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05217 Basal cell carcinoma - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05224 Breast cancer - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
AXIN1 hsa:8312 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APC AXIN1 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 26192618 7542250 8638126 8666229 association N/A ACSN
AXIN1 DVL1 10428961 16288291 16940750 19751508 22270359 26192618 8666229 interaction type N/A ACSN
AXIN1 PIN1 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26192618 26885856 interaction type N/A ACSN
MYC AXIN1 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26192618 26885856 interaction type N/A ACSN
CHUK AXIN1 11955436 11967263 12051714 12799363 23430059 26192618 7542250 8666229 interaction type N/A ACSN
BCL9 AXIN1 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 26192618 7542250 8666229 interaction type N/A ACSN
KLF8 AXIN1 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 26192618 7542250 8666229 interaction type N/A ACSN
AXIN1 CTNNB1 10228155 10488109 11940574 12000790 17208333 18988627 21071413 23180781 23331499 9734785 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink
AXIN1 TSC2 15972957 23180781 physical association anti tag coimmunoprecipitation InnateDB
AXIN1 AXIN1 16601693 17529994 21145463 22298955 26467481 interaction type,ubiquitination reaction,bind,up-regulates,up-regulates activity,down-regulates N/A Signor
AXIN1 MAP3K1 10575011 10829020 11884395 21071413 23331499 stimulation N/A SignaLink,SignaLink
APC2 AXIN1 10980707 23331499 stimulation N/A SignaLink,SignaLink
LRP5 AXIN1 11336703 18632848 21071413 23331499 stimulation N/A SignaLink,SignaLink
AXIN1 SMAD3 11438668 18988627 23331499 stimulation N/A SignaLink,SignaLink
AXIN1 CSNK1D 11818547 23331499 stimulation N/A SignaLink,SignaLink
LRP6 AXIN1 12897152 16340998 18988627 23331499 stimulation N/A SignaLink,SignaLink
SMURF1 AXIN1 23959799 ubiquitination reaction,inhibition N/A SignaLink
GSK3B AXIN1 10318824 10488109 10581160 12511557 16199882 17318175 18632848 19131971 21242974 21502811 23331499 9482734 9734785 stimulation N/A SignaLink
AXIN1 GSK3B 10228155 21502811 23331499 9554852 9734785 interaction type N/A SignaLink
PPP2CA AXIN1 19131971 23331499 9920888 stimulation N/A SignaLink
AXIN1 CSNK1A1L 11884395 23331499 stimulation N/A SignaLink
AXIN1 MAP3K4 12878610 23331499 stimulation N/A SignaLink
AXIN1 RNF111 14657019 16601693 23331499 stimulation N/A SignaLink
DVL3 AXIN1 10329628 12805222 23331499 interaction type N/A SignaLink
MACF1 AXIN1 16815997 23331499 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AXIN1 LRP5 11336703 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
AXIN1 LRP6 20005715 interaction type N/A PSP
AXIN1 PIAS1 20005715 interaction type N/A PSP
AXIN1 GSK3A 20005715 interaction type N/A PSP,SignaLink
AXIN1 GSK3B 20005715 interaction type N/A PSP
AXIN1 MAP3K1 20005715 interaction type N/A PSP,SignaLink
AXIN1 BTRC 10228155 20005715 21071413 interaction type N/A PSP,SignaLink
AXIN1 MAP3K4 20005715 interaction type N/A PSP
AXIN1 LRP6 20005715 N/A N/A SignaLink
AXIN1 GSK3B 20005715 20005715 N/A N/A SignaLink
AXIN1 MAP3K4 20005715 20005715 N/A N/A SignaLink
AXIN1 PIAS1 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 AXIN1 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
ETS1 AXIN1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 AXIN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 AXIN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 AXIN1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 AXIN1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C AXIN1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AXIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 AXIN1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00004E008F AXIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE AXIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD AXIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK5 AXIN1 22135298 phosphorylation N/A PhosphoSite
PPP2CA AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 PPP2CA 25361965 interaction type N/A PTMCode2
APC AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 APC 25361965 interaction type N/A PTMCode2
DVL2 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 DVL2 25361965 interaction type N/A PTMCode2
AXIN1 RNF111 25361965 interaction type N/A PTMCode2
RNF111 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 LRP5 25361965 interaction type N/A PTMCode2
LRP5 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 SENP2 25361965 interaction type N/A PTMCode2
SENP2 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 TSC1 25361965 interaction type N/A PTMCode2
TSC1 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 JUP 25361965 interaction type N/A PTMCode2
JUP AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 DAB2 25361965 interaction type N/A PTMCode2
DAB2 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 GSK3B 25361965 interaction type N/A PTMCode2
GSK3B AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 PPP2R5C 25361965 interaction type N/A PTMCode2
PPP2R5C AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 CSNK1E 25361965 interaction type N/A PTMCode2
CSNK1E AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 BTRC 25361965 interaction type N/A PTMCode2
BTRC AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 DVL1 25361965 interaction type N/A PTMCode2
DVL1 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 MAP3K4 25361965 interaction type N/A PTMCode2
MAP3K4 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 MAP3K1 25361965 interaction type N/A PTMCode2
MAP3K1 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 DIXDC1 25361965 interaction type N/A PTMCode2
DIXDC1 AXIN1 25361965 interaction type N/A PTMCode2
PPP2R5B AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 PPP2R5B 25361965 interaction type N/A PTMCode2
SMAD7 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 SMAD7 25361965 interaction type N/A PTMCode2
PPP2R5A AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 PPP2R5A 25361965 interaction type N/A PTMCode2
LRP6 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 LRP6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 AXIN1 19131971 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCK2 AXIN1 11557983 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAPRE1 AXIN1 25348397 N/A physical interaction ComPPI
GOLGA2 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DAXX AXIN1 25348397 N/A physical interaction ComPPI
KRTAP4-12 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STX11 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SKIL AXIN1 25348397 N/A physical interaction ComPPI
TNFAIP3 AXIN1 25348397 N/A physical interaction ComPPI
KRTAP4-2 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP2R1A AXIN1 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
KRT40 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LHX4 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CSNK1D AXIN1 25348397 N/A physical interaction ComPPI
MDFI AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZBTB26 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EGLN3 AXIN1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
SMURF2 AXIN1 25348397 N/A physical interaction ComPPI
DAB2 AXIN1 12805222 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RNF111 AXIN1 14525934 16601693 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vitro,in vivo ComPPI,HPRD,IntAct
SMAD7 AXIN1 14525934 16601693 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
MAPK3 AXIN1 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RUNX2 AXIN1 14525934 15262978 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMAD2 AXIN1 11438668 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SUMO1 AXIN1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TGIF1 AXIN1 24234451 25348397 25873176 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
SMAD3 AXIN1 11438668 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
USP7 AXIN1 17510365 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PIAS1 AXIN1 12223491 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
GSK3B AXIN1 10481074 10488109 10581160 11738041 14525934 17318175 17318191 17510365 17601533 19131971 19202075 19303846 19759537 21242974 21988832 22682247 22773187 23455922 23602568 24234451 24976009 25241761 25348397 26496610 29568061 9482734 9734785 phosphorylation reaction,colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,fluorescence polarization spectroscopy,pull down,physical interaction,protein kinase assay,in vitro,in vivo,confocal microscopy,tandem affinity purification,proximity ligation assay,proximity-dependent biotin identification,two hybrid ComPPI,HPRD,IntAct
JUP AXIN1 10488109 14525934 24234451 25348397 26496610 26871637 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
TUBG1 AXIN1 19390532 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
PPM1A AXIN1 10644691 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBB AXIN1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
UBC AXIN1 17510365 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
RPS27A AXIN1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
UBA52 AXIN1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
PRMT1 AXIN1 21242974 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
APC AXIN1 11297546 14525934 17510365 19131971 22682247 24234451 25348397 26496610 9734785 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
BTRC AXIN1 10228155 14525934 24234451 24976009 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
AXIN1 PPP2CB 25348397 N/A in vitro,in vivo ComPPI
AXIN1 DVL1 10330403 12556519 14525934 25348397 9482734 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
AXIN1 PPP2R5C 10698523 14525934 17510365 24234451 25348397 association experimental interaction detection,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
AXIN1 DVL2 10829020 14525934 21245303 22773187 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,in vivo ComPPI,HPRD,IntAct
AXIN1 LRP5 11336703 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
AXIN1 SENP2 11997515 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
AXIN1 PPP2CA 14525934 17510365 19131971 22682247 24234451 25348397 9920888 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
AXIN1 PPP2R5B 10698523 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
AXIN1 DIXDC1 14525934 15262978 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
AXIN1 CTNNB1 10488109 12000790 14525934 17318191 17510365 19166851 21242974 22682247 22773187 24234451 24976009 25348397 26496610 9734785 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
AXIN1 CRMP1 14525934 16169070 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid ComPPI,HPRD,IntAct
AXIN1 EEF1A1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AXIN1 ANP32A 14525934 16169070 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid ComPPI,HPRD,IntAct
AXIN1 DVL3 12805222 14525934 22682247 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
AXIN1 MAP3K4 14525934 15262978 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
AXIN1 LRP6 12897152 14525934 22682247 24234451 24976009 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
AXIN1 SH3GL1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AXIN1 GAK 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AXIN1 UTP14A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AXIN1 SMYD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 EEF1A1P5 25348397 N/A physical interaction ComPPI
AXIN1 MAP3K1 22682247 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 CSNK1A1 11884395 14525934 17318175 17510365 22682247 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
AXIN1 TSC1 25348397 N/A physical interaction ComPPI
AXIN1 TSC2 25348397 N/A physical interaction ComPPI
AXIN1 DVL1P1 25348397 N/A physical interaction ComPPI
AXIN1 PPP2R5A 19131971 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 AMER1 17510365 22682247 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
AXIN1 CARM1 25348397 N/A physical interaction ComPPI
AXIN1 MYC 19131971 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 GSK3A 17318175 17510365 23602568 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
AXIN1 STRAP 25348397 N/A physical interaction ComPPI
AXIN1 PML 21057547 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
AXIN1 TP53 21057547 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 HIPK2 25348397 N/A physical interaction ComPPI
AXIN1 HTT 25348397 N/A physical interaction ComPPI
AXIN1 AXIN2 22682247 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 SKI 25348397 N/A physical interaction ComPPI
AXIN1 PPP1CA 17318175 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 ARRB1 19202075 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 CAV1 25348397 N/A physical interaction ComPPI
AXIN1 SMURF1 25348397 N/A physical interaction ComPPI
AXIN1 LMO2 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
AXIN1 MYOT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AXIN1 GNAS 25348397 N/A physical interaction ComPPI
AXIN1 GNAS 25348397 N/A physical interaction ComPPI
AXIN1 GNAS 25348397 N/A physical interaction ComPPI
AXIN1 FBXW11 22682247 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 TNKS 25348397 N/A physical interaction ComPPI
AXIN1 XPO1 25348397 N/A physical interaction ComPPI
AXIN1 CTNNA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 PUF60 25348397 N/A physical interaction ComPPI
AXIN1 GAPVD1 25348397 N/A physical interaction ComPPI
AXIN1 ARHGAP21 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 MAP3K2 25348397 N/A physical interaction ComPPI
AXIN1 USP15 25348397 N/A physical interaction ComPPI
AXIN1 WDR26 17510365 24234451 25348397 27098453 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
AXIN1 FOXM1 25348397 N/A physical interaction ComPPI
AXIN1 NTAQ1 25348397 N/A physical interaction ComPPI
AXIN1 TRIM25 25348397 N/A physical interaction ComPPI
AXIN1 TRIM65 25348397 N/A physical interaction ComPPI
AXIN1 DAB2IP 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
AXIN1 NIN 19390532 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 TRIM29 19249679 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 AMMECR1 21304492 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 TNKS2 22153077 24234451 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
AXIN1 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 PSMD6 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 ZNF318 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 PHF6 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 RANBP2 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 USP9X 17510365 22682247 24234451 25348397 association anti bait coimmunoprecipitation,tandem affinity purification ComPPI,IntAct
AXIN1 YTHDC2 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 PSMD2 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 DLG1 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 DACT1 22470507 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 TFDP1 22773187 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 YAP1 24234451 24976009 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
AXIN1 WWTR1 24234451 24976009 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AXIN1 TRIM15 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 SUMO1P1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 TRIM27 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 TRIM37 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 CALCOCO2 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 PSTPIP1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 TRIP6 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 TFIP11 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 TRAF2 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AXIN1 FRAT1 10481074 24234451 25348397 phosphorylation reaction,association pull down,protein kinase assay ComPPI,IntAct
AXIN1 USP34 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AXIN1 GID8 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AXIN1 RANBP9 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AXIN1 RANBP10 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AXIN1 MAEA 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AXIN1 PPP2R2A 17510365 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CSNK1E AXIN1 11487578 12000790 14525934 21988832 22682247 24234451 25348397 26496610 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
AXIN1 AXIN1 14525934 16169070 21245303 24234451 9920888 physical association experimental interaction detection,light scattering,molecular sieving,nuclear magnetic resonance,two hybrid pooling approach HPRD,IntAct
AXIN1 GSK-3 17601533 24234451 N/A pull down IntAct
AXIN1 DDHD1 24234451 30021884 physical association cross-linking study IntAct
AXIN1 CALD1 24234451 30021884 physical association cross-linking study IntAct
H1-5 AXIN1 24234451 30021884 physical association cross-linking study IntAct
H1-2 AXIN1 24234451 30021884 physical association cross-linking study IntAct
H1-0 AXIN1 24234451 30021884 physical association cross-linking study IntAct
HNRNPA2B1 AXIN1 24234451 30021884 physical association cross-linking study IntAct
AXIN1 CTNNB1 10196136 10228155 10318824 10330181 10488109 11940574 12000790 12421363 12805222 16199882 16890161 17053159 17208333 17318191 18593713 18632848 19131971 19166851 20128690 20531388 21242974 22509369 22682247 23959799 26496610 27898060 9482734 9501208 9554852 9601641 9734785 inhibition,stimulant N/A OmniPath
AXIN1 CSNK1A1 11884395 12000790 17318175 26496610 27898060 stimulant N/A OmniPath
CSNK1A1 AXIN1 11884395 12000790 17318175 26496610 27898060 stimulant N/A OmniPath
APC2 AXIN1 27898060 9601641 stimulant N/A OmniPath
AXIN1 MYC 19131971 20399964 27898060 stimulant N/A OmniPath
AXIN1 MAP3K1 10575011 10829020 11408485 11884395 12878610 20128690 24135036 27898060 stimulant N/A OmniPath
CSNK1E AXIN1 11487578 11884395 12000790 21988832 26496610 27898060 stimulant N/A OmniPath
LRP5 AXIN1 11336703 18632848 1863285 18762581 19075000 27898060 stimulant N/A OmniPath
PPM1A AXIN1 10644691 27898060 inhibition N/A OmniPath
AXIN1 GSK3A 10196136 11707456 17318175 19131971 23602568 23959799 26496610 27898060 9482734 9501208 9601641 stimulant N/A OmniPath
LRP6 AXIN1 12897152 16341 16890161 18632848 19107203 20128690 22682247 23959799 27898060 inhibition,stimulant N/A OmniPath
DVL3 AXIN1 1032963 12805222 20128690 22682247 27898060 N/A N/A OmniPath
PPP1CB AXIN1 17318175 27898060 inhibition N/A OmniPath
SUMO1 AXIN1 12223491 27898060 N/A N/A OmniPath
AXIN1 CSNK1D 11818547 12000790 27898060 stimulant N/A OmniPath
CSNK1D AXIN1 12000790 27898060 stimulant N/A OmniPath
PPP1CA AXIN1 17318175 27898060 inhibition N/A OmniPath
AXIN1 APC 10228155 11297546 16199882 20128690 22682247 23277359 26496610 27898060 9554852 9734785 stimulant N/A OmniPath
AXIN1 MAP3K4 12878610 15262978 27898060 stimulant N/A OmniPath
PPP2CA AXIN1 10421629 10644691 19131971 27898060 9920888 stimulant N/A OmniPath
DVL1 AXIN1 10330181 10330403 10428961 10862053 11027605 11113207 11278246 12556519 18339531 18632848 27898060 9482734 inhibition N/A OmniPath
AXIN1 GSK3B 10228155 10318824 10330181 10330403 10488109 10535959 10581160 12511557 12554650 12584189 14734535 16199882 16293724 16568235 16890161 17318175 17318191 17601533 18593713 18632848 19131971 19202075 19303846 19759537 20128690 21242974 21502811 21988832 22270359 22509369 22613765 22682247 23455922 23602568 23959799 24451375 25241761 26496610 27898060 9482734 9501208 9554852 9601641 9734785 inhibition,stimulant N/A OmniPath
GSK3B AXIN1 10228155 10318824 10330181 10330403 10488109 10535959 10581160 12511557 12554650 12584189 14734535 16199882 16293724 16568235 16890161 17318175 17318191 17601533 18593713 18632848 19131971 19202075 19303846 19759537 20128690 21242974 21502811 21988832 22270359 22509369 22613765 22682247 23455922 23579495 23602568 23959799 24451375 25241761 26496610 27898060 9482734 9501208 9554852 9601641 9734785 stimulant N/A OmniPath
AXIN1 SMAD3 11438668 27898060 stimulant N/A OmniPath
DVL2 AXIN1 10829020 17529994 21245303 27898060 stimulant N/A OmniPath
AXIN1 BMPR1A 21145463 22298955 27898060 inhibition N/A OmniPath
AXIN1 RNF111 14657019 1465702 16601693 27898060 stimulant N/A OmniPath
AXIN1 SMAD7 16601693 27898060 inhibition,stimulant N/A OmniPath
GNAS AXIN1 16293724 27898060 stimulant N/A OmniPath
PPP1CC AXIN1 17318175 27898060 inhibition N/A OmniPath
TNKS2 AXIN1 19759537 22153077 27898060 inhibition N/A OmniPath
AMER1 AXIN1 17510365 20128690 21304492 26496610 27898060 stimulant N/A OmniPath
PPP2CB AXIN1 10421629 27898060 9920888 N/A N/A OmniPath
TNKS AXIN1 19759537 22153077 27898060 inhibition N/A OmniPath

Visualization










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