GENE：CDH3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CDH3 |
| FullNmae | cadherin 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1762 |
| EnsembleID | ENSG00000062038 |
| Uniprot | P22223 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CDH3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CDH3 | GO:0000902,GO:0001895,GO:0003674,GO:0005509,GO:0005737,GO:0005886,GO:0005886,GO:0005912,GO:0007043,GO:0007155,GO:0007156,GO:0007275,GO:0007601,GO:0009410,GO:0010628,GO:0010838,GO:0016339,GO:0016342,GO:0022405,GO:0030054,GO:0031424,GO:0032773,GO:0032912,GO:0034332,GO:0043568,GO:0044331,GO:0045296,GO:0048023,GO:0051796,GO:0060901,GO:0090263,GO:1902910 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CDH3 | hsa:1001 | path:hsa04514 | Cell adhesion molecules - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CDH3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | CDH3 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | CDH3 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | CDH3 | 21878914 22120723 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXA1 | CDH3 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CDH3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | CDH3 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CDH3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CDH3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CDH3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CDH3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CDH3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CDH3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| BRCA1 | CDH3 | 19882246 22120723 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HOXA9 | CDH3 | 25023983 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | CDH3 | 19882246 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | CDH3 | 19882246 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | CDH3 | 19882246 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDH3 | CTNNA1 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNNA1 | CDH3 | 25361965 | interaction type | N/A | PTMCode2 |
| CDH3 | CTNNB1 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNNB1 | CDH3 | 25361965 | interaction type | N/A | PTMCode2 |
| CDH3 | CTNND1 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNND1 | CDH3 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CTNND1 | CDH3 | 14525934 25348397 8660921 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| JUP | CDH3 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | CDH3 | 25348397 | N/A | physical interaction | ComPPI |
| CFTR | CDH3 | 25348397 | N/A | physical interaction | ComPPI |
| YAP1 | CDH3 | 21376238 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CTNNB1 | CDH3 | 10381631 11889072 12800191 14525934 25348397 8227214 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| CTNNA1 | CDH3 | 10381631 14525934 1924379 25348397 8227214 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| AP2M1 | CDH3 | 24189400 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| CDH3 | CTNNA3 | 25348397 | N/A | physical interaction | ComPPI |
| CDH3 | PCDHGB1 | 25348397 | N/A | physical interaction | ComPPI |
| IGF1R | CDH3 | 21317933 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct,OmniPath |
| CDH3 | CDH3 | 11909859 14525934 | N/A | experimental interaction detection | HPRD |
| CTNND1 | CDH3 | 14610055 23180380 27898060 8660921 | stimulant | N/A | OmniPath |
| ARVCF | CDH3 | 14610055 27898060 | stimulant | N/A | OmniPath |
| CTNND2 | CDH3 | 14610055 27898060 | stimulant | N/A | OmniPath |