Gene Information gene info

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GENE：CLCN3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CLCN3
FullNmae chloride voltage-gated channel 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2021
EnsembleID ENSG00000109572
Uniprot P51790

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CLCN3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CLCN3 GO:0000139,GO:0005247,GO:0005254,GO:0005254,GO:0005515,GO:0005524,GO:0005765,GO:0005769,GO:0005769,GO:0005770,GO:0005794,GO:0005794,GO:0005886,GO:0006885,GO:0006911,GO:0008021,GO:0008021,GO:0008344,GO:0009897,GO:0009986,GO:0010008,GO:0012506,GO:0015297,GO:0016020,GO:0016020,GO:0030141,GO:0030165,GO:0031410,GO:0031901,GO:0031902,GO:0032587,GO:0035249,GO:0042581,GO:0043231,GO:0043679,GO:0045335,GO:0045494,GO:0045794,GO:0048388,GO:0051932,GO:0055037,GO:0072320,GO:0097401,GO:0098978,GO:1902476,GO:1903428

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CLCN3 hsa:1182 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CLCN3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CLCN3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CLCN3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CLCN3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CLCN3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CLCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CLCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CLCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CLCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CLCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 CLCN3 21880628 25416803 mrna cleavage,inhibition array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 CLCN3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000521626 CLCN3 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000039A25B CLCN3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000250A40 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000031D186 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB CLCN3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 CLCN3 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC CLCN3 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB CLCN3 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A CLCN3 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B CLCN3 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 CLCN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC CLCN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE CLCN3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D CLCN3 23824327 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS00001CC0F4 CLCN3 23824327 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS000075D50C CLCN3 23824327 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS00002F74F1 CLCN3 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS000034B6F5 CLCN3 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS00002FAA8C CLCN3 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS0000381CEC CLCN3 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAMK2A CLCN3 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
LGALS3 CLCN3 25348397 N/A physical interaction ComPPI
SLC9A3R1 CLCN3 11967229 12471024 14525934 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CFTR CLCN3 25348397 N/A physical interaction ComPPI
PDZK1 CLCN3 12471024 14525934 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HSPB1 CLCN3 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
GGA1 CLCN3 25348397 N/A physical interaction ComPPI
LGALS8 CLCN3 25348397 N/A physical interaction ComPPI
TRIM25 CLCN3 25348397 N/A physical interaction ComPPI
CLCN3 GOPC 12471024 14525934 24234451 25348397 9843494 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CLCN3 PDZK1P1 25348397 N/A physical interaction ComPPI
CLCN3 LGALS9 25348397 N/A physical interaction ComPPI
CLCN3 LYPD3 25348397 N/A physical interaction ComPPI
CLCN3 TMEM9B 25348397 N/A physical interaction ComPPI
CLCN3 TPCN2 25348397 N/A physical interaction ComPPI
CLCN3 CLCN3 12471024 14525934 N/A experimental interaction detection HPRD
CHCHD3 CLCN3 24234451 30021884 physical association cross-linking study IntAct
H2BC21 CLCN3 24234451 30021884 physical association cross-linking study IntAct
SLC9A3R2 CLCN3 11967229 27898060 N/A N/A OmniPath
CAMK2A CLCN3 14754994 23165767 27898060 N/A N/A OmniPath
GOPC CLCN3 12471024 27898060 9843494 N/A N/A OmniPath
PDZK1 CLCN3 12471024 27898060 N/A N/A OmniPath

Visualization










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